Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data preweaning lethality, incomplete penetrance Lyst homozygote male Early adult Viability Primary Screen Homozygous males viability TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_VIA_063_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_063_001&phenotyping_center=TCP Eye - MPATH pathological process term developmental dysplasia Lyst homozygote female Early adult Histopathology Eye - MPATH pathological process term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:107448?anatomy="Eye" preweaning lethality, incomplete penetrance Lyst homozygote not_considered Early adult Viability Primary Screen Homozygous animals viability TCP IMPC 0.0 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_VIA_067_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_067_001&phenotyping_center=TCP Ear - MPATH pathological process term inflammation Lyst homozygote male Early adult Histopathology Ear - MPATH pathological process term TCP IMPC 0.0 //www.mousephenotype.org/data/histopath/MGI:107448?anatomy="Ear" abnormal coat/hair pigmentation Lyst homozygote male Early adult Combined SHIRPA and Dysmorphology Coat - color - head TCP IMPC 1.44E-24 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_CSD_006_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_006_001&phenotyping_center=TCP abnormal coat/hair pigmentation Lyst homozygote male Early adult Combined SHIRPA and Dysmorphology Coat - color - back TCP IMPC 1.44E-24 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_CSD_005_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_005_001&phenotyping_center=TCP abnormal coat/hair pigmentation Lyst homozygote male Early adult Combined SHIRPA and Dysmorphology Coat - color - abdomen TCP IMPC 6.27E-21 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_CSD_007_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_007_001&phenotyping_center=TCP abnormal iris morphology Lyst homozygote male Early adult Eye Morphology Iris/Pupil TCP IMPC 1.35E-17 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_EYE_010_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_010_001&phenotyping_center=TCP abnormal coat/hair pigmentation Lyst homozygote female Early adult Combined SHIRPA and Dysmorphology Coat - color - head TCP IMPC 2.68E-16 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_CSD_006_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_006_001&phenotyping_center=TCP abnormal coat/hair pigmentation Lyst homozygote female Early adult Combined SHIRPA and Dysmorphology Coat - color - back TCP IMPC 2.68E-16 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_CSD_005_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_005_001&phenotyping_center=TCP abnormal iris morphology Lyst homozygote female Early adult Eye Morphology Iris/Pupil TCP IMPC 9.96E-15 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_EYE_010_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_010_001&phenotyping_center=TCP abnormal retina morphology Lyst homozygote female Early adult Eye Morphology Retina (combined) TCP IMPC 3.69E-14 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_EYE_092_002&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_092_002&phenotyping_center=TCP abnormal coat/hair pigmentation Lyst homozygote female Early adult Combined SHIRPA and Dysmorphology Coat - color - abdomen TCP IMPC 5.15E-12 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_CSD_007_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_007_001&phenotyping_center=TCP abnormal retina morphology Lyst homozygote male Early adult Eye Morphology Retina (combined) TCP IMPC 5.68E-8 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_EYE_092_002&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_092_002&phenotyping_center=TCP decreased locomotor activity Lyst homozygote female Early adult Open Field Center resting time TCP IMPC 5.34E-7 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_OFD_015_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_OFD_001¶meter_stable_id=IMPC_OFD_015_001&phenotyping_center=TCP increased mean corpuscular hemoglobin Lyst homozygote male Early adult Hematology Mean corpuscular hemoglobin TCP IMPC 1.89E-6 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_HEM_006_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_006_001&phenotyping_center=TCP increased fasting circulating glucose level Lyst homozygote not_considered Early adult Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration TCP IMPC 1.13E-5 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_IPG_010_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_IPG_001¶meter_stable_id=IMPC_IPG_010_001&phenotyping_center=TCP increased grip strength Lyst homozygote male Early adult Grip Strength Forelimb grip strength normalised against body weight TCP IMPC 4.24E-5 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_GRS_010_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_010_001&phenotyping_center=TCP increased mean corpuscular volume Lyst homozygote male Early adult Hematology Mean cell volume TCP IMPC 7.41E-5 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_HEM_005_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_005_001&phenotyping_center=TCP decreased prepulse inhibition Lyst homozygote not_considered Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI4 TCP IMPC 8.29E-5 //www.mousephenotype.org/data/charts?accession=MGI:107448&allele_accession_id=MGI:5513800&zygosity=homozygote¶meter_stable_id=IMPC_ACS_036_001&pipeline_stable_id=TCP_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_036_001&phenotyping_center=TCP