Gene: Ppm1a

Name protein phosphatase 1A, magnesium dependent, alpha isoform

Synonyms
  • Mpp alpha
  • 2310003C21Rik
  • MPPa-1
  • 2900017D14Rik
  • MMPa-2

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:99878   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Ppm1a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ppm1a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal bone structure Ppm1atm1b(EUCOMM)Hmgu HOM Female postnatal 1.58E-5
decreased fasted circulating glucose level Ppm1atm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.07E-5
limb grasping Ppm1atm1b(EUCOMM)Hmgu HOM Male postnatal 8.78E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No (2/354) (1/1)
Aorta 1 No (2/530) (1/1)
Bone 1 No (1/515) (1/1)
Brain 1 No (8/530) (1/1)
Brainstem 1 No (5/530) (1/1)
Brown adipose tissue 1 No (1/1)
Cartilage tissue 1 No (1/530) (1/1)
Cerebellum 1 No (6/530) (1/1)
Cerebral cortex 1 No (6/530) (1/1)
Esophagus 1 No (1/354) (1/1)
Eye 1 No (1/530) (1/1)
Gall bladder 1 No (1/1)
Heart 1 No (4/530) (1/1)
Hippocampus 1 No (7/530) (1/1)
Hypothalamus 1 No (5/529) (1/1)
Kidney 1 No (13/530) (1/1)
Large intestine 1 No (7/530) (1/1)
Liver 1 No
Lower urinary tract 1 No (3/530) (1/1)
Lung 1 No (4/530) (1/1)
Lymph node 1 No (2/530) (1/1)
Mammary gland 1 No
Olfactory lobe 1 No (3/354) (1/1)
Oral epithelium 1 No (1/1)
Ovary 1 No (1/530)
Oviduct 1 No (1/530)
Pancreas 1 No (2/530) (1/1)
Parathyroid gland 1 No (2/516) (1/1)
Peripheral nervous system 1 No (4/530) (1/1)
Peyer's patch 1 No (1/354) (1/1)
Pituitary gland 1 No (2/530) (1/1)
Prostate gland 1 No (3/530) (1/1)
Skeletal muscle 1 No (1/1)
Skin 1 No (2/530) (1/1)
Small intestine 1 No (5/530) (1/1)
Spinal cord 1 No (5/530) (1/1)
Spleen 1 No (3/530)
Stomach 1 No (5/530) (1/1)
Striatum 1 No (6/530) (1/1)
Testis 1 No (7/530) (1/1)
Thymus 1 No (1/530) (1/1)
Thyroid gland 1 No (11/530) (1/1)
Trachea 1 No (5/530) (1/1)
Uterus 1 No (1/530)
Vascular system 1 No (1/354) (1/1)
White adipose tissue 1 No (1/1)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/413) (4/4)
Ear 2 (2/4)
Embryo 2 (4/4)
Eye 2 (4/4)
Foot 2 (4/4)
Forebrain 2 (4/4)
Forelimb 2 (4/4)
Hand 2 (4/4)
Head 2 (4/413) (4/4)
Heart 2 (2/4)
Hindbrain 2 (5/413) (4/4)
Hindlimb 2 (4/4)
Liver 2 (1/4)
Lung 2 (2/4)
Mandibular process 2 (2/4)
Maxillary process 2 (2/4)
Midbrain 2 (4/4)
Oral cavity 2 (2/4)
Skin 2
Tail 2 (4/4)
Tail somite 2 (2/4)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    3 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Ppm1atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ppm1atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene