Gene: Cntfr

Order

Name ciliary neurotrophic factor receptor

Synonyms Cntfralpha

Status ES CellsMice
tm1a
phenotype data available

Links MGI:99605    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Cntfr

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cntfr data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Cntfrtm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (1/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (1/2)
Striatum 2 No
Testis 2 No (2/584)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse digestive system nervous system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (6)
  • Cntfrtm1a(EUCOMM)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    stomach, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI

show all 6 images

nervous system (4)
  • Cntfrtm1a(EUCOMM)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
trunk (3)
  • Cntfrtm1a(EUCOMM)Wtsi
    stomach, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
digestive system (1)
  • Cntfrtm1a(EUCOMM)Wtsi
    stomach, HET, Female, WTSI
urinary system (1)
  • Cntfrtm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (110)
  • Cntfrtm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    forearm, WT, Male, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    body, WT, Male, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    body, WT, Male, WTSI
  • Cntfrtm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI

show all 110 images

Skin Histopathology (1)
  • Cntfrtm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cntfrtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cntfrtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Cntfrtm376(L1L2_gt0)
Vector
Gene