Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Gzmm by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Leishmaniasis, Tegumentary, Susceptibility To | Tegumentary leishmaniasis susceptibility | OMIM:602068 | |
Human Coronavirus Sensitivity | Susceptibility to coronavirus 229e | OMIM:122460 | |
Varicella, Severe Recurrent | Severe recurrent varicella | OMIM:600670 | |
Coxsackievirus B3 Susceptibility | Recurrent viral infections | OMIM:120050 | |
Ciliary Discoordination Due To Random Ciliary Orientation | Recurrent infections | OMIM:215518 | |
Immunodeficiency 30 | Recurrent mycobacterial infections, Recurrent infections | OMIM:614891 | |
Immunodeficiency 28 | Recurrent mycobacterial infections | OMIM:614889 | |
Neutrophil Actin Dysfunction | Recurrent bacterial infections | OMIM:257150 | |
Immunodeficiency 31B | Recurrent mycobacterial infections, Herpes simplex encephalitis, Recurrent viral infections | OMIM:613796 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Gzmmtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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