Gene: Hira

Order

Name histone cell cycle regulator

Synonyms
  • Tuple1
  • Gm15797
  • D16Ertd95e

Status ES CellsMice
tm1a
phenotype data available

Links MGI:99430    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Hira

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Hira data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Hiratm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased leukocyte cell number Hiratm1a(EUCOMM)Wtsi HET Female Male postnatal 2.85E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No
Esophagus 2 No (1/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584) (1/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse respiratory system digestive system cardiovascular system nervous system set of connective tissues reproductive system immune system exocrine system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (19)
  • Hiratm1a(EUCOMM)Wtsi
    trachea, thyroid gland, parathyroid gland, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    oviduct, ovary, uterus, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI

show all 19 images

trunk (15)
  • Hiratm1a(EUCOMM)Wtsi
    trachea, thyroid gland, parathyroid gland, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    oviduct, ovary, uterus, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI

show all 15 images

digestive system (4)
  • Hiratm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    peyer's patch, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    peyer's patch, HET, Female, WTSI
immune system (4)
  • Hiratm1a(EUCOMM)Wtsi
    mesenteric lymph node, lymph node, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    peyer's patch, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    peyer's patch, HET, Female, WTSI
nervous system (3)
  • Hiratm1a(EUCOMM)Wtsi
    peripheral nervous system, pituitary gland, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
reproductive system (3)
  • Hiratm1a(EUCOMM)Wtsi
    oviduct, ovary, uterus, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
endocrine system (2)
  • Hiratm1a(EUCOMM)Wtsi
    trachea, thyroid gland, parathyroid gland, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
respiratory system (2)
  • Hiratm1a(EUCOMM)Wtsi
    trachea, thyroid gland, parathyroid gland, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
urinary system (2)
  • Hiratm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
cardiovascular system (1)
  • Hiratm1a(EUCOMM)Wtsi
    heart, HET, Female, WTSI
exocrine system (1)
  • Hiratm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
set of connective tissues (1)
  • Hiratm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (243)
  • Hiratm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    body, WT, Male, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    body, HET, Male, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    head, HET, Male, WTSI

show all 243 images

Tail Epidermis Wholemount (3)
  • Hiratm1a(EUCOMM)Wtsi
    abnormal epidermis stratum basale morphology, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    abnormal epidermis stratum basale morphology, HET, Female, WTSI
  • Hiratm1a(EUCOMM)Wtsi
    abnormal epidermis stratum basale morphology, HET, Female, WTSI
Eye Morphology (1)
  • Hiratm1a(EUCOMM)Wtsi
    eye, cornea/lens fusion, corneal opacity, HET, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Hiratm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene