Gene: Slc20a2

Order

Name solute carrier family 20, member 2

Synonyms
  • Pit-2
  • MolPit2
  • Ram-1
  • PiT-2
  • Ram1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:97851    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable     Homozygous - Subviable

Phenotype associations for Slc20a2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slc20a2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Brain - mineralisation Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 0.0
Eye with optic nerve - developmental dysplasia Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 0.0
Sternum - developmental and structural abnormality Slc20a2tm1a(EUCOMM)Wtsi HOM Male postnatal 0.0
preweaning lethality, incomplete penetrance Slc20a2tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased body length Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.2E-12
abnormal lens morphology Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.56E-12
cataract Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.56E-12
abnormal incisor color Slc20a2tm1a(EUCOMM)Wtsi HOM Female postnatal 5.92E-11
decreased lean body mass Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.2E-9
abnormal iris morphology Slc20a2tm1a(EUCOMM)Wtsi HOM Female postnatal 3.92E-9
decreased bone mineral content Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 4.54E-9
increased circulating alkaline phosphatase level Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.89E-8
abnormal bone structure Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 5.04E-8
kyphosis Slc20a2tm1a(EUCOMM)Wtsi HOM Male postnatal 9.02E-8
decreased bone mineral density Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.5E-7
impaired glucose tolerance Slc20a2tm1b(EUCOMM)Wtsi HET Female Male postnatal 3.46E-7
abnormal spine curvature Slc20a2tm1a(EUCOMM)Wtsi HOM Male postnatal 8.71E-7
decreased total body fat amount Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.83E-6
absent pinna reflex Slc20a2tm1a(EUCOMM)Wtsi HOM Female postnatal 4.3E-6
abnormal lens morphology Slc20a2tm1b(EUCOMM)Wtsi HET Female Male postnatal 7.5E-6
decreased fasted circulating glucose level Slc20a2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 8.55E-6
increased grip strength Slc20a2tm1a(EUCOMM)Wtsi HET Male postnatal 1.28E-5
abnormal vocalization Slc20a2tm1b(EUCOMM)Wtsi HET Male postnatal 1.74E-5
eyelids fail to open Slc20a2tm1a(EUCOMM)Wtsi HOM Male postnatal 5.73E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Blood 2 No
Bone 2 No (1/539)
Bone marrow 2 No
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cecum 2 No (1/355)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Chest bone 2 No
Colon 2 No (1/99)
Cranium 2 No
Diaphragm 2 No
Epididymis 2 No (4/106)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Harderian gland 2 No
Heart 2 No (3/562) (2/2)
Hindlimb 2 No
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Main olfactory bulb 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540)
Parotid gland 2 No
Penis 2 No (1/2)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (1/2)
Stomach pyloric region 2 No
Striatum 2 No (4/562)
Sublingual gland 2 No
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Tongue 2 No
Trachea 2 No (3/562)
Trigeminal V nerve 2 No
Urinary bladder 2 No
Uterus 2 No (2/562)
Vagina 2 No
Vas deferens 2 No (1/360)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    digestive system
    cardiovascular system
    nervous system
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    66 Images
  • X-ray: XRay Images Dorso Ventral
    93 Images
  • X-ray: XRay Images Forepaw
    24 Images
  • X-ray: XRay Images Skull Lateral Orientation
    25 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    27 Images
  • Adult LacZ: LacZ Images Wholemount
    15 Images
  • X-ray: XRay Images Hind Leg and Hip
    1 Images
Legacy Phenotype Associated Images
Xray (180)
  • Slc20a2tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Slc20a2tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Slc20a2tm1a(EUCOMM)Wtsi
    HET, Female, WTSI
  • Slc20a2tm1a(EUCOMM)Wtsi
    HET, Female, WTSI
  • Slc20a2tm1a(EUCOMM)Wtsi
    HET, Female, WTSI

show all 180 images

Eye Morphology (44)
  • Slc20a2tm1a(EUCOMM)Wtsi
    cataracts, HOM, Male, WTSI
  • Slc20a2tm1a(EUCOMM)Wtsi
    abnormal placement of pupils, abnormal pupil morphology, HOM, Female, WTSI
  • Slc20a2tm1a(EUCOMM)Wtsi
    abnormal pupil morphology, abnormal placement of pupils, HOM, Male, WTSI
  • Slc20a2tm1a(EUCOMM)Wtsi
    corneal opacity, HET, Male, WTSI
  • Slc20a2tm1a(EUCOMM)Wtsi
    corneal vascularization, HET, Male, WTSI

show all 44 images

Dysmorphology (1)
  • Slc20a2tm1a(EUCOMM)Wtsi
    HINDLIMB, AUTOPOD, HET, Female, WTSI
Embryo Dysmorphology (1)
  • Slc20a2tm1a(EUCOMM)Wtsi
    HOM, Unsexed, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Slc20a2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slc20a2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Slc20a2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene