Gene: Mep1a

Order

Name meprin 1 alpha

Synonyms
  • meprin A alpha-subunit
  • Mep-1
  • Mep1
  • Mep-1a
  • meprin alpha

Status ES CellsMice
tm1a
phenotype data available

Links MGI:96963    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Mep1a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mep1a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased lean body mass Mep1atm1a(KOMP)Wtsi HOM Female postnatal 4.48E-6
increased lean body mass Mep1atm1a(KOMP)Wtsi HOM Male postnatal 4.48E-6
decreased total body fat amount Mep1atm1a(KOMP)Wtsi HOM Male postnatal 5.59E-6
increased total body fat amount Mep1atm1a(KOMP)Wtsi HOM Female postnatal 5.59E-6
decreased fasted circulating glucose level Mep1atm1a(KOMP)Wtsi HOM Male postnatal 8.93E-6

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • DSS Histology
    7 Images
Legacy Phenotype Associated Images
Xray (16)
  • Mep1atm1a(KOMP)Wtsi
    WT, Female, WTSI
  • Mep1atm1a(KOMP)Wtsi
    WT, Female, WTSI
  • Mep1atm1a(KOMP)Wtsi
    WT, Female, WTSI
  • Mep1atm1a(KOMP)Wtsi
    WT, Female, WTSI
  • Mep1atm1a(KOMP)Wtsi
    WT, Female, WTSI

show all 16 images

Dysmorphology (5)
  • Mep1atm1a(KOMP)Wtsi
    HEAD, abnormal snout morphology, short snout, HOM, Male, WTSI
  • Mep1atm1a(KOMP)Wtsi
    HEAD, abnormal snout morphology, asymmetric snout, HOM, Male, WTSI
  • Mep1atm1a(KOMP)Wtsi
    abnormal snout morphology, HEAD, asymmetric snout, HOM, Male, WTSI
  • Mep1atm1a(KOMP)Wtsi
    HEAD, abnormal snout morphology, asymmetric snout, HOM, Female, WTSI
  • Mep1atm1a(KOMP)Wtsi
    abnormal snout morphology, asymmetric snout, HEAD, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Mep1atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Mep1atm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene