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Gene: Hoxd8 MGI:96209

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
homeobox D8
Synonyms:
Hox-5.4,  4921540P06Rik,  Hox-4.3

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hoxd8 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Hoxd8 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Cervical Rib
Cervical ribs OMIM:117900
Neurogenic Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:100073
Short-Rib Thoracic Dysplasia 17 With Or Without Polydactyly
Lateral clavicle hook, Postaxial hand polydactyly, Postaxial foot polydactyly, Trident acetabulum... OMIM:617405
Thoracomelic Dysplasia
Bell-shaped thorax, Short ribs OMIM:273740
Thoracic Dysostosis, Isolated
Pectus excavatum, Short ribs, Bell-shaped thorax OMIM:187750
Radioulnar Synostosis-Microcephaly-Scoliosis Syndrome
Finger syndactyly, Abnormality of the elbow, Abnormal rib morphology, Pectus carinatum, Radioulna... ORPHA:3268
Hypo- And Hypermelanotic Cutaneous Macules-Retarded Growth-Intellectual Disability Syndrome
Abnormal rib morphology ORPHA:2435
Spondylometaphyseal Dysplasia, Type A4
Brachydactyly, Coxa valga, Metaphyseal sclerosis, Enlargement of the costochondral junction, Meta... OMIM:609052
Kyphomelic Dysplasia
Bowing of the long bones, Anterior rib cupping, Missing ribs, Lateral clavicle hook, Short thorax... ORPHA:1801
Thoracolaryngopelvic Dysplasia
Metaphyseal widening, Irregular chondrocostal junctions, Bell-shaped thorax, Narrow pelvis bone, ... OMIM:187760
Acrodysplasia Scoliosis
Vertebral segmentation defect, Spina bifida occulta, Scoliosis, Brachydactyly ORPHA:2956
Short-Rib Thoracic Dysplasia 11 With Or Without Polydactyly
Postaxial polydactyly, Lateral clavicle hook, Bell-shaped thorax, Short long bone, Thoracic dyspl... OMIM:615633
Hypersulfaturia
Costochondral pain OMIM:620372
Jeune Syndrome
Abnormal clavicle morphology, Toe syndactyly, Postaxial hand polydactyly, Short thorax, Abnormal ... ORPHA:474
Mesomelic Dysplasia, Kantaputra Type
Camptodactyly of finger, Tarsal synostosis, Abnormality of the humerus, Abnormal rib morphology, ... ORPHA:1836
Thin Ribs-Tubular Bones-Dysmorphism Syndrome
Slender long bone, Abnormal pelvic girdle bone morphology, Abnormal rib morphology ORPHA:1506
Congenital Pseudoarthrosis Of The Clavicle
Congenital pseudoarthrosis of the clavicle, Osteoarthritis, Cervical ribs ORPHA:66630
Spondylometaphyseal Dysplasia, A4 Type
Flared, irregular rib ends, Coxa vara, Short palm ORPHA:168555
Spondyloepimetaphyseal Dysplasia, Irapa Type
Short metacarpal, Osteoarthritis, Abnormal joint morphology, Abnormal carpal morphology, Short me... ORPHA:93351
Fibrochondrogenesis 2
Thoracic hypoplasia, Hypoplastic ilia, Cupped ribs, Metaphyseal widening, Hypoplastic pubic bone,... OMIM:614524
Metatropic Dysplasia
Abnormal metaphyseal vascular invasion, Enlarged joints, Long coccyx, Halberd-shaped pelvis, Narr... OMIM:156530
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies
Superior rib anomalies OMIM:307500
Craniodiaphyseal Dysplasia
Abnormal rib morphology, Diaphyseal thickening ORPHA:1513
Pierre Robin Sequence With Pectus Excavatum And Rib And Scapular Anomalies
Pectus excavatum, Hypoplastic distal segments of scapulae, Abnormal rib morphology OMIM:602196
Spondyloepimetaphyseal Dysplasia, Borochowitz-Cormier-Daire Type
Dysplastic iliac wing, Metaphyseal spurs, Bowing of the legs, Pectus excavatum, Metaphyseal widen... OMIM:608728
Heart Defects-Limb Shortening Syndrome
Abnormal metaphysis morphology, Abnormal rib morphology, Narrow chest ORPHA:1354
Endosteal Hyperostosis, Worth Type
Clavicular sclerosis, Abnormal rib morphology, Diaphyseal thickening ORPHA:2790
Metaphyseal Chondrodysplasia, Schmid Type
Broad proximal phalanges of the hand, Bowing of the legs, Short tubular bones of the hand, Proxim... ORPHA:174
Axial Spondylometaphyseal Dysplasia
Thoracic scoliosis, Proximal femoral metaphyseal irregularity, Coxa vara, Deformed rib cage, Narr... ORPHA:168549
Poland Syndrome
Syndactyly, Unilateral oligodactyly, Unilateral brachydactyly, Rib fusion, Short ribs, Sprengel a... OMIM:173800
Grant Syndrome
Joint dislocation, Bowing of the long bones, Abnormal rib morphology, Abnormal pelvic girdle bone... ORPHA:2097
Spondylocostal Dysostosis 3, Autosomal Recessive
Contracture of the proximal interphalangeal joint of the 2nd finger, Rib fusion, Slender finger OMIM:609813
Spondylomegaepiphyseal Dysplasia With Upper Limb Mesomelia, Punctate Calcifications, And Deafness
Broad toe, Enlarged metacarpal epiphyses, Cupped ribs, Enlarged epiphyses of the phalanges of the... OMIM:609616
Hemangiomas, Cavernous, Of Face And Supraumbilical Midline Raphe
Bifid sternum, Supraumbilical raphe OMIM:140850
Holt-Oram Syndrome
Finger syndactyly, Abnormal clavicle morphology, Down-sloping shoulders, Absent thumb, Abnormalit... ORPHA:392
Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:97330
Metatropic Dysplasia
Camptodactyly of finger, Abnormal rib morphology, Long thorax, Halberd-shaped pelvis, Narrow ches... ORPHA:2635
Sprengel Deformity
Rib segmentation abnormalities, Sprengel anomaly OMIM:184400
Spondylocostal Dysostosis 5
Vertebral fusion, Missing ribs, Pectus carinatum, Posterior rib fusion, Supernumerary ribs OMIM:122600
Spondyloepimetaphyseal Dysplasia, Missouri Type
Radial bowing, Osteoarthritis, Ulnar bowing, Flared metaphysis, Coxa vara, Tibial bowing, Femoral... OMIM:602111
Osteogenesis Imperfecta, Type Ix
Beaded ribs, Pectus excavatum, Pectus carinatum, Wormian bones, Short lower limbs OMIM:259440
Cloverleaf Skull-Multiple Congenital Anomalies Syndrome
Abnormal clavicle morphology, Bowing of the long bones, Proximal placement of thumb, Abnormal rib... ORPHA:93267
Metaphyseal Dysostosis, Impaired Intellectual Development, And Conductive Deafness
Metaphyseal dysplasia, Brachydactyly, Irregular iliac crest, Cupped ribs, Metaphyseal widening, F... OMIM:250420
Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3
Hypoplasia of the ulna, Tapered finger, Multiple joint dislocation, Hip dislocation, Thin ribs, K... OMIM:618395
10Q22.3Q23.3 Microduplication Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:276422
Spondylocostal Dysostosis 2, Autosomal Recessive
Rib fusion OMIM:608681
Juberg-Hayward Syndrome
Toe syndactyly, Short thumb, Hypoplasia of the radius, Abnormal finger morphology, Abnormal rib m... ORPHA:2319
Diastrophic Dysplasia
Joint dislocation, Abnormal clavicle morphology, Bowing of the long bones, Camptodactyly of finge... ORPHA:628
Acrocapitofemoral Dysplasia
Short proximal phalanx of thumb, Coxa vara, Pectus carinatum, Narrow chest, Short palm, Hypoplast... OMIM:607778
Spondylometaphyseal Dysplasia With Cone-Rod Dystrophy
Short metacarpal, Cupped ribs, Metaphyseal widening, Coxa vara, Tibial bowing, Femoral bowing, Na... OMIM:608940
Fibrochondrogenesis 1
Narrow greater sciatic notch, Short palm, Clinodactyly of the 5th finger, Widely patent sagittal ... OMIM:228520
Microcephalic Primordial Dwarfism, Toriello Type
Abnormal rib morphology, Abnormal epiphysis morphology, Brachydactyly ORPHA:2643
Autosomal Dominant Spondylocostal Dysostosis
Short thorax, Posterior rib fusion, Abnormal rib morphology, Missing ribs ORPHA:1797
Osteogenesis Imperfecta, Type Ii
Crumpled long bones, Broad long bones, Beaded ribs, Tibial bowing, Thin ribs, Bell-shaped thorax,... OMIM:166210
Short-Rib Thoracic Dysplasia 19 With Or Without Polydactyly
Syndactyly, Thoracic hypoplasia, Postaxial polydactyly, Hypoplastic ilia, Lateral clavicle hook, ... OMIM:617895
Hypophosphatasia
Bowing of the long bones, Craniosynostosis, Abnormal rib morphology, Narrow chest, Abnormal metap... ORPHA:436
Femoral-Facial Syndrome
Short femur, Abnormal rib morphology, Rib fusion, Coxa vara, Abnormal fibula morphology, Abnormal... ORPHA:1988
Cat-Eye Syndrome
Hip dysplasia, Abnormal rib morphology ORPHA:195
Spondylometaphyseal Dysplasia, Algerian Type
Metaphyseal dysplasia, Bowed humerus, Anterior rib cupping, Short tubular bones of the hand, Tibi... OMIM:184253
Mosaic Trisomy 14
Narrow chest, Abnormal rib morphology, Camptodactyly of finger ORPHA:1703
Isolated Klippel-Feil Syndrome
Abnormal rib morphology, Abnormal shoulder morphology, Cervical C2/C3 vertebral fusion, Sprengel ... ORPHA:2345
Dyggve-Melchior-Clausen Disease
Glenoid fossa hypoplasia, Coxa vara, Pectus carinatum, Broad ribs, Iliac crest serration, Horizon... ORPHA:239
White Forelock With Malformations
Clinodactyly of the 5th finger, Finger syndactyly, Sprengel anomaly, Abnormal rib morphology ORPHA:2475
Becker Nevus Syndrome
Pectus excavatum, Abnormal tibia morphology, Rib fusion, Pectus carinatum, Supernumerary ribs ORPHA:64755
Intellectual Disability-Polydactyly-Uncombable Hair Syndrome
Broad hallux phalanx, Toe syndactyly, Metatarsus valgus, Aplasia/Hypoplasia of toe, Postaxial han... ORPHA:3082
Fibrochondrogenesis
Hypoplastic scapulae, Camptodactyly of finger, Abnormal rib morphology, Bell-shaped thorax, Abnor... ORPHA:2021
Achondrogenesis Type 1B
Short foot, Short thorax, Abnormal rib morphology, Narrow chest ORPHA:93298
Microcephaly-Cervical Spine Fusion Anomalies Syndrome
Abnormal clavicle morphology, Pectus excavatum, Abnormal rib morphology, Fused cervical vertebrae... ORPHA:2522
Melnick-Needles Syndrome
Bowing of the long bones, Coxa valga, Short thorax, Abnormal rib morphology, Hip dislocation, Con... ORPHA:2484
Lethal Congenital Contracture Syndrome Type 1
Slender long bone, Abnormality of the elbow, Abnormal rib morphology, Abnormal hip bone morphology ORPHA:1486
Platyspondylic Lethal Skeletal Dysplasia, Torrance Type
Radial bowing, Thoracic hypoplasia, Dumbbell-shaped long bone, Hypoplastic ischia, Hypoplastic il... OMIM:151210
Mayer-Rokitansky-Küster-Hauser Syndrome Type 2
Abnormal rib morphology ORPHA:2578
Craniosynostosis, Herrmann-Opitz Type
Finger syndactyly, Craniosynostosis, Split hand, Abnormal rib morphology, Brachydactyly ORPHA:2145
Kenny-Caffey Syndrome, Type 1
Long clavicles, Delayed closure of the anterior fontanelle, Thin clavicles, Small hand, Thin ribs... OMIM:244460
Mucolipidosis Iii Alpha/Beta
Soft tissue swelling of interphalangeal joints, Craniosynostosis, Irregular carpal bones, Split h... OMIM:252600
Achondrogenesis, Type Ia
Abnormal femoral metaphysis morphology, Barrel-shaped chest, Hypoplastic scapulae, Bowing of the ... OMIM:200600
Growth Delay-Hydrocephaly-Lung Hypoplasia Syndrome
Bowing of the long bones, Radial bowing, Abnormal rib morphology, Abnormal fibula morphology, Tib... ORPHA:3035
Kyphomelic Dysplasia
Short humerus, Short metacarpal, Radial bowing, Short femur, Bowed humerus, Anterior rib cupping,... OMIM:211350
Short-Rib Thoracic Dysplasia 3 With Or Without Polydactyly
Hypoplasia of the ulna, Metaphyseal spurs, Postaxial polydactyly, Thoracic hypoplasia, Lateral cl... OMIM:613091
Eiken Syndrome
Broad femoral neck, Delayed epiphyseal ossification, Long thumb, Flat acetabular roof, Fibular hy... OMIM:600002
Spondylometaphyseal Dysplasia, Sedaghatian Type
Delayed epiphyseal ossification, Long fibula, Narrow greater sciatic notch, Narrow chest, Short p... OMIM:250220
Cooper-Jabs Syndrome
Camptodactyly of finger, Proximal placement of thumb, Missing ribs, Abnormal rib morphology, Abno... ORPHA:1488
Ellis-Van Creveld Syndrome
Capitate-hamate fusion, Postaxial hand polydactyly, Genu valgum, Postaxial foot polydactyly, Pect... OMIM:225500
Cenani-Lenz Syndrome
Hypoplasia of the ulna, Finger syndactyly, Toe syndactyly, Elbow dislocation, Short thumb, Hypopl... ORPHA:3258
Renpenning Syndrome
Pectus excavatum, Abnormal thumb morphology, Abnormal rib morphology, Clinodactyly of the 5th fin... ORPHA:3242
Phaver Syndrome
Broad hallux phalanx, Camptodactyly of finger, Short thumb, Abnormal rib morphology, Ulnar deviat... ORPHA:2876
Microcephaly-Seizures-Intellectual Disability-Heart Disease Syndrome
Postaxial hand polydactyly, Abnormal rib morphology, Abnormal sternum morphology, Short ribs, Bro... ORPHA:2519
Antley-Bixler Syndrome
Arachnodactyly, Camptodactyly of finger, Craniosynostosis, Abnormal rib morphology, Femoral bowin... ORPHA:83
Mullerian Duct Aplasia, Unilateral Renal Agenesis, And Cervicothoracic Somite Anomalies
Sprengel anomaly, Abnormal rib morphology OMIM:601076
Klippel-Feil Syndrome 1, Autosomal Dominant
Cervical C2/C3 vertebral fusion, Sprengel anomaly, Abnormal vertebral segmentation and fusion, Ab... OMIM:118100
Male Hypergonadotropic Hypogonadism-Intellectual Disability-Skeletal Anomalies Syndrome
Abnormal rib morphology, Abnormality of the humeroulnar joint ORPHA:2234
Imperforate Oropharynx-Costovertebral Anomalies Syndrome
Clinodactyly of the 5th finger, Abnormal rib morphology, Arachnodactyly, Missing ribs ORPHA:2759
Hydrocephalus-Costovertebral Dysplasia-Sprengel Anomaly Syndrome
Sandal gap, Sprengel anomaly, Abnormal rib morphology, Brachydactyly ORPHA:2180
Cleidocranial Dysplasia
Wormian bones, Hypoplastic scapulae, Down-sloping shoulders, Tapered finger, Abnormal thumb morph... ORPHA:1452
Congenital Osteogenesis Imperfecta-Microcephaly-Cataracts Syndrome
Abnormal rib morphology ORPHA:2772
Short-Rib Thoracic Dysplasia 1 With Or Without Polydactyly
Hypoplasia of the ulna, Lateral clavicle hook, Early ossification of capital femoral epiphyses, C... OMIM:208500
Septopreoptic Holoprosencephaly
Abnormal rib morphology ORPHA:280195
Mucopolysaccharidosis Type 4
Joint dislocation, Bowing of the long bones, Coxa valga, Short thorax, Abnormal rib morphology, G... ORPHA:582
Laryngotracheoesophageal Cleft Type 4
Abnormal rib morphology ORPHA:93941
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome
Proximal placement of thumb, Abnormal thumb morphology, Short thumb, Preaxial hand polydactyly, A... ORPHA:1120
Spondylometaphyseal Dysplasia, Sedaghatian Type
Short metacarpal, Iliac crest serration, Abnormal scapula morphology, Metaphyseal chondrodysplasi... ORPHA:93317
Autosomal Recessive Spondylocostal Dysostosis
Rib segmentation abnormalities, Finger syndactyly, Camptodactyly of finger, Short thorax, Rib fus... ORPHA:2311
X-Linked Hypophosphatemia
Shortening of the talar neck, Bowing of the long bones, Craniosynostosis, Bowing of the legs, Bea... ORPHA:89936
Intellectual Disability-Myopathy-Short Stature-Endocrine Defect Syndrome
Clinodactyly of the 5th finger, Abnormal rib morphology, Abnormal hip bone morphology, Pectus car... ORPHA:3068
Spondyloepimetaphyseal Dysplasia, X-Linked
Pectus carinatum, Long fibula, Short palm, Short phalanx of finger, Broad metacarpals, Genu varum... OMIM:300106
Oculocerebrocutaneous Syndrome
Finger syndactyly, Congenital hip dislocation, Aplasia/Hypoplasia of the distal phalanges of the ... ORPHA:1647
Poland Syndrome
Aplasia/Hypoplasia of the thumb, Pectus carinatum, Abnormal sternum morphology, Finger syndactyly... ORPHA:2911
Pyknoachondrogenesis
Hypoplastic ischia, Short iliac bones, Short thorax, Abnormal iliac wing morphology, Enlarged tho... ORPHA:3003
Cole-Carpenter Syndrome
Crumpled long bones, Bowing of the long bones, Abnormal rib morphology, Wormian bones, Abnormal m... ORPHA:2050
Holzgreve Syndrome
Hand polydactyly, Abnormal rib morphology, Abnormal morphology of ulna, Abnormal metacarpal morph... ORPHA:2167
Campomelia, Cumming Type
Bowing of the long bones, Abnormal thorax morphology, Abnormal rib morphology, Clubbing of toes, ... ORPHA:1318
Trisomy 13
Postaxial hand polydactyly, Abnormal rib morphology, Abnormal pelvic girdle bone morphology, Ectr... ORPHA:3378
Prune Belly Syndrome
Pectus excavatum, Congenital hip dislocation, Abnormal rib morphology ORPHA:2970
Otopalatodigital Syndrome Type 2
Bowing of the long bones, Tarsal synostosis, Short hallux, Camptodactyly of finger, Elbow disloca... ORPHA:90652
Cartilage-Hair Hypoplasia
Metaphyseal dysplasia, Bowing of the long bones, Abnormal distal phalanx morphology of finger, Fl... ORPHA:175
Trisomy 1Q
Toe syndactyly, Arachnodactyly, Camptodactyly of finger, Preaxial hand polydactyly, Short thorax,... ORPHA:261344
Ulna And Fibula, Absence Of, With Severe Limb Deficiency
Femoral bowing, Pectus carinatum, Foot oligodactyly, Aplasia/Hypoplasia of the tarsal bones, Phoc... OMIM:276820
Axial Mesodermal Dysplasia Spectrum
Abnormality of the knee, Abnormal pelvic girdle bone morphology, Abnormal rib morphology, Missing... ORPHA:1834
Multiple Pterygium-Malignant Hyperthermia Syndrome
Finger syndactyly, Prominent metopic ridge, Arachnodactyly, Camptodactyly of finger, Tapered fing... ORPHA:2215
Familial Osteodysplasia, Anderson Type
Aplastic clavicle, Missing ribs, Elbow dislocation, Abnormal rib morphology, Bifid femur, Aplasia... ORPHA:2769
Autosomal Dominant Popliteal Pterygium Syndrome
Finger syndactyly, Toe syndactyly, Split hand, Abnormal rib morphology, Popliteal pterygium ORPHA:1300
Congenital Adrenal Hyperplasia Due To Cytochrome P450 Oxidoreductase Deficiency
Femoral bowing, Narrow chest, Abnormality of the wrist, Elbow ankylosis, Short metacarpal, Abnorm... ORPHA:95699
Tetraamelia-Multiple Malformations Syndrome
Aplasia/Hypoplasia involving the pelvis, Abnormal rib morphology, Missing ribs ORPHA:3301
Radio-Renal Syndrome
Hypoplasia of the radius, Abnormal rib morphology, Abnormality of the elbow, Short palm, Brachyda... ORPHA:3015
Mosaic Trisomy 8
Camptodactyly of finger, Patellar aplasia, Abnormal rib morphology, Narrow pelvis bone, Narrow ch... ORPHA:96061
Aspergillosis
Abnormal long bone morphology, Abnormal rib morphology ORPHA:1163
Schwartz-Jampel Syndrome
Hip contracture, Bowing of the long bones, Shoulder flexion contracture, Protrusio acetabuli, Cox... ORPHA:800
Fibrous Dysplasia Of Bone
Abnormal morphology of the radius, Bowing of the long bones, Abnormal pelvis bone morphology, Abn... ORPHA:249
Hurler Syndrome
Abnormal clavicle morphology, Camptodactyly of finger, Abnormality of the elbow, Abnormal rib mor... ORPHA:93473
Alagille Syndrome
Clinodactyly of the 5th finger, Hypoplasia of the ulna, Abnormal rib morphology, Short distal pha... ORPHA:52
Vacterl/Vater Association
Preaxial hand polydactyly, Finger syndactyly, Aplasia/Hypoplasia of the radius, Abnormal rib morp... ORPHA:887
Osteogenesis Imperfecta
Abnormal tibia morphology, Osteoarthritis, Abnormal femur morphology, Femoral bowing, Abnormal lo... ORPHA:666
Myhre Syndrome
Brachydactyly, Abnormal rib morphology, Abnormal epiphysis morphology, Short palm, Large iliac wi... ORPHA:2588
Dextrocardia
Congenital hip dislocation, Abnormal rib morphology ORPHA:1666
Ear-Patella-Short Stature Syndrome
Camptodactyly of finger, Aplastic clavicle, Craniosynostosis, Elbow dislocation, Patellar aplasia... ORPHA:2554
Camptodactyly Syndrome, Guadalajara Type 3
Abnormal rib morphology, Small hand, Short foot, Thickened cortex of long bones, Broad femoral neck ORPHA:488434
Ulbright-Hodes Syndrome
Short humerus, Short metacarpal, Humeroradial synostosis, Abnormal rib morphology, Hypoplasia of ... ORPHA:3404
Trisomy 18
Camptodactyly of finger, Postaxial hand polydactyly, Abnormal rib morphology, Deviation of finger... ORPHA:3380
Monosomy 9Q22.3
Pectus excavatum, Polydactyly, Abnormal rib morphology, Metopic synostosis ORPHA:77301
Hereditary Acrokeratotic Poikiloderma
Finger syndactyly, Camptodactyly of finger, Abnormal rib morphology, Abnormal hip bone morphology... ORPHA:2907
Simpson-Golabi-Behmel Syndrome
Vertebral fusion, Finger syndactyly, Congenital hip dislocation, Toe syndactyly, Camptodactyly of... ORPHA:373
Autosomal Recessive Malignant Osteopetrosis
Bowing of the long bones, Craniosynostosis, Abnormal rib morphology, Abnormal epiphysis morpholog... ORPHA:667
Smith-Lemli-Opitz Syndrome
Finger syndactyly, Proximal placement of thumb, Postaxial hand polydactyly, Split hand, Abnormal ... ORPHA:818
Mucopolysaccharidosis Type 3
Abnormal clavicle morphology, Avascular necrosis of the capital femoral epiphysis, Abnormal rib m... ORPHA:581
Vater/Vacterl Association
Syndactyly, Absent radius, Short thumb, Hypoplasia of the radius, Abnormal rib morphology, Preaxi... OMIM:192350
Kindler Epidermolysis Bullosa
Finger syndactyly, Camptodactyly of finger, Abnormal rib morphology, Short 4th metacarpal, Short ... ORPHA:2908
Monosomy 9P
Abnormality of the tarsal bones, Postaxial hand polydactyly, Abnormal rib morphology, Proximal pl... ORPHA:261112
Oculocerebrorenal Syndrome Of Lowe
Abnormal rib morphology, Hip dislocation, Genu valgum, Arthritis, Joint swelling, Abnormal epiphy... ORPHA:534
Pagod Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:991
Alagille Syndrome 1
Hypoplasia of the ulna, Abnormal rib morphology, Short distal phalanx of finger OMIM:118450
Townes-Brocks Syndrome
Broad hallux phalanx, Toe syndactyly, Preaxial hand polydactyly, Partial duplication of thumb pha... ORPHA:857
Charge Syndrome
Abnormal tibia morphology, Abnormal rib morphology, Bifid femur, Clinodactyly of the 5th finger, ... ORPHA:138
Charge Syndrome
Hypoplasia of the ulna, Down-sloping shoulders, Absent radius, Short thumb, Radial head subluxati... OMIM:214800

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hoxd8

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hoxd8.

No publications found that use IMPC mice or data for Hoxd8.

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MGI Allele Allele Type Produced
Hoxd8tm459029(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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