banner
Genes Phenotypes Help, News, Blog

Gene: Hoxb7 MGI:96188

Log in to follow
Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
homeobox B7
Synonyms:
Hox-2.3

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hoxb7 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Hoxb7 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Cervical Rib
Cervical ribs OMIM:117900
Neurogenic Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:100073
Spondylocostal Dysostosis 3, Autosomal Recessive
Contracture of the proximal interphalangeal joint of the 2nd finger, Rib fusion, Slender finger OMIM:609813
Thoracomelic Dysplasia
Bell-shaped thorax, Short ribs OMIM:273740
Short-Rib Thoracic Dysplasia 17 With Or Without Polydactyly
Lateral clavicle hook, Postaxial hand polydactyly, Postaxial foot polydactyly, Trident acetabulum... OMIM:617405
Thoracic Dysostosis, Isolated
Pectus excavatum, Short ribs, Bell-shaped thorax OMIM:187750
Poland Syndrome
Syndactyly, Unilateral oligodactyly, Rib fusion, Unilateral brachydactyly, Short ribs, Sprengel a... OMIM:173800
Spondylocostal Dysostosis 2, Autosomal Recessive
Rib fusion OMIM:608681
Hypo- And Hypermelanotic Cutaneous Macules-Retarded Growth-Intellectual Disability Syndrome
Abnormal rib morphology ORPHA:2435
Radioulnar Synostosis-Microcephaly-Scoliosis Syndrome
Finger syndactyly, Abnormal rib morphology, Pectus carinatum, Radioulnar synostosis, Clinodactyly... ORPHA:3268
Spondylocostal Dysostosis 5
Pectus carinatum, Posterior rib fusion, Supernumerary ribs, Missing ribs OMIM:122600
Spondylometaphyseal Dysplasia, Type A4
Brachydactyly, Coxa valga, Metaphyseal sclerosis, Enlargement of the costochondral junction, Meta... OMIM:609052
Becker Nevus Syndrome
Pectus excavatum, Abnormal tibia morphology, Rib fusion, Pectus carinatum, Supernumerary ribs ORPHA:64755
Hypersulfaturia
Costochondral pain OMIM:620372
Femoral-Facial Syndrome
Short femur, Rib fusion, Abnormal rib morphology, Coxa vara, Abnormal fibula morphology, Abnormal... ORPHA:1988
Thoracolaryngopelvic Dysplasia
Metaphyseal widening, Irregular chondrocostal junctions, Bell-shaped thorax, Narrow pelvis bone, ... OMIM:187760
Autosomal Dominant Spondylocostal Dysostosis
Short thorax, Posterior rib fusion, Abnormal rib morphology, Missing ribs ORPHA:1797
Kyphomelic Dysplasia
Bowing of the long bones, Anterior rib cupping, Missing ribs, Lateral clavicle hook, Short thorax... ORPHA:1801
Short-Rib Thoracic Dysplasia 11 With Or Without Polydactyly
Postaxial polydactyly, Lateral clavicle hook, Bell-shaped thorax, Short long bone, Thoracic dyspl... OMIM:615633
Thoracopelvic Dysostosis
Short ribs OMIM:187770
Thin Ribs-Tubular Bones-Dysmorphism Syndrome
Slender long bone, Abnormal pelvic girdle bone morphology, Abnormal rib morphology ORPHA:1506
Jeune Syndrome
Abnormal clavicle morphology, Toe syndactyly, Postaxial hand polydactyly, Short thorax, Abnormal ... ORPHA:474
Spondylometaphyseal Dysplasia, A4 Type
Flared, irregular rib ends, Coxa vara, Short palm ORPHA:168555
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies
Superior rib anomalies OMIM:307500
Spondylocostal Dysostosis 1, Autosomal Recessive
Rib fusion OMIM:277300
Craniodiaphyseal Dysplasia
Abnormal rib morphology, Diaphyseal thickening ORPHA:1513
Pierre Robin Sequence With Pectus Excavatum And Rib And Scapular Anomalies
Pectus excavatum, Hypoplastic distal segments of scapulae, Abnormal rib morphology OMIM:602196
Fibrochondrogenesis 2
Hypoplastic ischia, Hypoplastic ilia, Cupped ribs, Metaphyseal widening, Hypoplastic pubic bone, ... OMIM:614524
Heart Defects-Limb Shortening Syndrome
Abnormal metaphysis morphology, Abnormal rib morphology, Narrow chest ORPHA:1354
Hemangiomas, Cavernous, Of Face And Supraumbilical Midline Raphe
Bifid sternum, Supraumbilical raphe OMIM:140850
Endosteal Hyperostosis, Worth Type
Clavicular sclerosis, Abnormal rib morphology, Diaphyseal thickening ORPHA:2790
Mesomelic Dysplasia, Kantaputra Type
Camptodactyly of finger, Tarsal synostosis, Abnormality of the humerus, Abnormal rib morphology, ... ORPHA:1836
Congenital Pseudoarthrosis Of The Clavicle
Congenital pseudoarthrosis of the clavicle, Cervical ribs ORPHA:66630
Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:97330
Autosomal Recessive Spondylocostal Dysostosis
Rib segmentation abnormalities, Finger syndactyly, Camptodactyly of finger, Short thorax, Rib fus... ORPHA:2311
Metatropic Dysplasia
Abnormal metaphyseal vascular invasion, Long coccyx, Halberd-shaped pelvis, Narrow chest, Flaring... OMIM:156530
Metaphyseal Chondrodysplasia, Schmid Type
Broad proximal phalanges of the hand, Bowing of the legs, Short tubular bones of the hand, Proxim... ORPHA:174
Spondylocostal Dysostosis 4, Autosomal Recessive
Missing ribs, Pectus excavatum, Short thorax, Rib fusion, Bell-shaped thorax OMIM:613686
Spondyloepimetaphyseal Dysplasia, Borochowitz-Cormier-Daire Type
Dysplastic iliac wing, Metaphyseal spurs, Bowing of the legs, Pectus excavatum, Metaphyseal widen... OMIM:608728
Spondyloepimetaphyseal Dysplasia, Irapa Type
Short metacarpal, Short metatarsal, Abnormal rib morphology, Abnormal carpal morphology, Coxa var... ORPHA:93351
Congenital Disorder Of Glycosylation, Type Iig
Thoracic scoliosis, Squared iliac bones, Rib fusion, Posterior rib gap, Small hand, Ulnar deviati... OMIM:611209
Sprengel Deformity
Rib segmentation abnormalities, Sprengel anomaly OMIM:184400
Axial Spondylometaphyseal Dysplasia
Thoracic scoliosis, Proximal femoral metaphyseal irregularity, Deformed rib cage, Coxa vara, Narr... ORPHA:168549
Spondylomegaepiphyseal Dysplasia With Upper Limb Mesomelia, Punctate Calcifications, And Deafness
Broad toe, Enlarged metacarpal epiphyses, Cupped ribs, Enlarged epiphyses of the phalanges of the... OMIM:609616
Becker Nevus Syndrome
Pectus excavatum, Cervical ribs OMIM:604919
Cerebrofaciothoracic Dysplasia
Sprengel anomaly, Rib fusion, Narrow chest, Bifid ribs ORPHA:1394
Holt-Oram Syndrome
Abnormal clavicle morphology, Finger syndactyly, Down-sloping shoulders, Absent thumb, Pectus exc... ORPHA:392
Metatropic Dysplasia
Camptodactyly of finger, Abnormal rib morphology, Long thorax, Halberd-shaped pelvis, Narrow ches... ORPHA:2635
10Q22.3Q23.3 Microduplication Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:276422
Grant Syndrome
Bowing of the long bones, Abnormal rib morphology, Abnormal pelvic girdle bone morphology, Narrow... ORPHA:2097
Spondylocostal Dysostosis With Anal Atresia And Urogenital Anomalies
Rib fusion, Short ribs, Missing ribs, Thin ribs OMIM:271520
Cloverleaf Skull-Multiple Congenital Anomalies Syndrome
Abnormal clavicle morphology, Bowing of the long bones, Proximal placement of thumb, Abnormal rib... ORPHA:93267
Microcephalic Primordial Dwarfism, Toriello Type
Abnormal rib morphology, Abnormal epiphysis morphology, Brachydactyly ORPHA:2643
Metaphyseal Dysostosis, Impaired Intellectual Development, And Conductive Deafness
Metaphyseal dysplasia, Brachydactyly, Irregular iliac crest, Cupped ribs, Metaphyseal widening, F... OMIM:250420
Pontine Tegmental Cap Dysplasia
Rib fusion OMIM:614688
Osteogenesis Imperfecta, Type Ix
Pectus excavatum, Pectus carinatum, Short lower limbs, Beaded ribs OMIM:259440
Kbg Syndrome
Syndactyly, Rib fusion, Cutaneous syndactyly, Cervical ribs, Thoracic kyphosis, Radial deviation ... OMIM:148050
Robinow Syndrome, Autosomal Recessive 1
Short palm, Duplication of the distal phalanx of hand, Dislocated radial head, Radial bowing, Rib... OMIM:268310
Cat-Eye Syndrome
Hip dysplasia, Abnormal rib morphology ORPHA:195
Spondylometaphyseal Dysplasia With Cone-Rod Dystrophy
Short metacarpal, Cupped ribs, Metaphyseal widening, Coxa vara, Tibial bowing, Femoral bowing, Na... OMIM:608940
Proximal 16P11.2 Microdeletion Syndrome
Hand polydactyly, Rib fusion ORPHA:261197
Multiple Pterygium Syndrome, Escobar Variant
Syndactyly, Long clavicles, Arachnodactyly, Down-sloping shoulders, Rocker bottom foot, Patellar ... OMIM:265000
Autosomal Recessive Multiple Pterygium Syndrome
Finger syndactyly, Camptodactyly of finger, Pectus excavatum, Rib fusion, Symphalangism affecting... ORPHA:2990
Spondyloepimetaphyseal Dysplasia, Missouri Type
Radial bowing, Ulnar bowing, Flared metaphysis, Coxa vara, Tibial bowing, Femoral bowing, Flatten... OMIM:602111
Global Developmental Delay-Alopecia-Macrocephaly-Facial Dysmorphism-Structural Brain Anomalies Syndrome
Clinodactyly of the 5th finger, Rib fusion, Tapered toe, Tapered finger ORPHA:544488
White Forelock With Malformations
Clinodactyly of the 5th finger, Finger syndactyly, Sprengel anomaly, Abnormal rib morphology ORPHA:2475
Acrocapitofemoral Dysplasia
Short proximal phalanx of thumb, Coxa vara, Pectus carinatum, Narrow chest, Short palm, Hypoplast... OMIM:607778
Spondylometaphyseal Dysplasia, Algerian Type
Metaphyseal dysplasia, Bowed humerus, Anterior rib cupping, Short tubular bones of the hand, Tibi... OMIM:184253
Short-Rib Thoracic Dysplasia 19 With Or Without Polydactyly
Syndactyly, Thoracic hypoplasia, Postaxial polydactyly, Lateral clavicle hook, Hypoplastic ilia, ... OMIM:617895
Mosaic Trisomy 14
Camptodactyly of finger, Abnormal rib morphology, Narrow chest ORPHA:1703
Chondrodysplasia With Platyspondyly, Distinctive Brachydactyly, Hydrocephaly, And Microphthalmia
11 pairs of ribs, Metaphyseal cupping of proximal phalanges, Thin ribs, Metaphyseal cupping of me... OMIM:300863
Mayer-Rokitansky-Küster-Hauser Syndrome Type 2
Abnormal rib morphology ORPHA:2578
Hypophosphatasia
Bowing of the long bones, Abnormal rib morphology, Narrow chest, Abnormal metaphysis morphology ORPHA:436
Pallister-Hall Syndrome
Syndactyly, Mesoaxial foot polydactyly, Toe syndactyly, Mesoaxial hand polydactyly, Postaxial han... OMIM:146510
Craniofacial Dysmorphism, Skeletal Anomalies, And Impaired Intellectual Development Syndrome 1
Hyperextensibility of the finger joints, Overlapping toe, Pectus excavatum, Long fingers, Postaxi... OMIM:213980
Autosomal Recessive Robinow Syndrome
Finger syndactyly, Broad hallux phalanx, Toe syndactyly, Brachydactyly, Sandal gap, Camptodactyly... ORPHA:1507
Intellectual Disability-Polydactyly-Uncombable Hair Syndrome
Broad hallux phalanx, Toe syndactyly, Metatarsus valgus, Aplasia/Hypoplasia of toe, Postaxial han... ORPHA:3082
Lymphangiectasia, Intestinal
Prominent floating ribs OMIM:152800
Aicardi Syndrome
Missing ribs, Small hand, Rib fusion, Hip dysplasia, Supernumerary ribs, Bifid ribs ORPHA:50
Achondrogenesis Type 1B
Short foot, Short thorax, Abnormal rib morphology, Narrow chest ORPHA:93298
Osteogenesis Imperfecta, Type Ii
Crumpled long bones, Broad long bones, Beaded ribs, Tibial bowing, Bell-shaped thorax, Thin ribs,... OMIM:166210
Fibrochondrogenesis
Hypoplastic scapulae, Camptodactyly of finger, Abnormal rib morphology, Bell-shaped thorax, Abnor... ORPHA:2021
Diastrophic Dysplasia
Abnormal clavicle morphology, Bowing of the long bones, Camptodactyly of finger, Proximal placeme... ORPHA:628
Femoral-Facial Syndrome
Short third metatarsal, Short humerus, Short fourth metatarsal, Toe syndactyly, Short fifth metat... OMIM:134780
Juberg-Hayward Syndrome
Toe syndactyly, Short thumb, Hypoplasia of the radius, Abnormal finger morphology, Abnormal rib m... ORPHA:2319
Fibrochondrogenesis 1
Hypoplastic scapulae, Long clavicles, Anterior rib cupping, Dumbbell-shaped long bone, Broad long... OMIM:228520
Growth Delay-Hydrocephaly-Lung Hypoplasia Syndrome
Bowing of the long bones, Radial bowing, Abnormal rib morphology, Abnormal fibula morphology, Tib... ORPHA:3035
Microcephaly-Cervical Spine Fusion Anomalies Syndrome
Pectus excavatum, Abnormal clavicle morphology, Abnormal rib morphology, Abnormal hip bone morpho... ORPHA:2522
Autosomal Recessive Kenny-Caffey Syndrome
Stenosis of the medullary cavity of the long bones, Thin clavicles, Small hand, Thin ribs, Short ... ORPHA:93324
Melnick-Needles Syndrome
Bowing of the long bones, Coxa valga, Short thorax, Abnormal rib morphology, Hip dislocation, Con... ORPHA:2484
Microphthalmia, Syndromic 3
Rib fusion, Supernumerary ribs, Missing ribs OMIM:206900
Platyspondylic Lethal Skeletal Dysplasia, Torrance Type
Radial bowing, Dumbbell-shaped long bone, Hypoplastic ischia, Hypoplastic ilia, Hypoplastic pubic... OMIM:151210
Isolated Klippel-Feil Syndrome
Abnormal shoulder morphology, Sprengel anomaly, Abnormal rib morphology ORPHA:2345
Aicardi Syndrome
Proximal placement of thumb, Missing ribs, Rib fusion, Supernumerary ribs, Bifid ribs OMIM:304050
Lethal Congenital Contracture Syndrome Type 1
Slender long bone, Abnormal rib morphology, Abnormal hip bone morphology ORPHA:1486
Craniosynostosis, Herrmann-Opitz Type
Finger syndactyly, Split hand, Abnormal rib morphology, Brachydactyly ORPHA:2145
Osteogenesis Imperfecta, Type Xv
Thin ribs OMIM:615220
Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3
Hypoplasia of the ulna, Tapered finger, Hip dislocation, Thin ribs, Delayed ossification of carpa... OMIM:618395
Achondrogenesis, Type Ia
Barrel-shaped chest, Abnormal femoral metaphysis morphology, Hypoplastic scapulae, Beaded ribs, B... OMIM:200600
Kenny-Caffey Syndrome, Type 1
Long clavicles, Thin clavicles, Small hand, Thin ribs, Short foot, Slender long bone, Short palm OMIM:244460
Dyggve-Melchior-Clausen Disease
Epiphyseal dysplasia, Metaphyseal dysplasia, Abnormal pelvis bone morphology, Glenoid fossa hypop... ORPHA:239
Mullerian Duct Aplasia, Unilateral Renal Agenesis, And Cervicothoracic Somite Anomalies
Sprengel anomaly, Abnormal rib morphology OMIM:601076
Achondrogenesis, Type Ii
Barrel-shaped chest, Broad long bones, Short tubular bones of the hand, Short long bone, Short ri... OMIM:200610
Wolf-Hirschhorn Syndrome
Rib segmentation abnormalities, Hypoplastic pubic ramus, Arachnodactyly, Short hallux, Short thum... ORPHA:280
Cooper-Jabs Syndrome
Camptodactyly of finger, Proximal placement of thumb, Missing ribs, Abnormal rib morphology, Abno... ORPHA:1488
Eiken Syndrome
Broad femoral neck, Delayed epiphyseal ossification, Long thumb, Flat acetabular roof, Fibular hy... OMIM:600002
Mucolipidosis Iii Alpha/Beta
Soft tissue swelling of interphalangeal joints, Irregular carpal bones, Split hand, Short long bo... OMIM:252600
Microcephaly-Seizures-Intellectual Disability-Heart Disease Syndrome
Postaxial hand polydactyly, Abnormal rib morphology, Abnormal sternum morphology, Short ribs, Bro... ORPHA:2519
Short-Rib Thoracic Dysplasia 3 With Or Without Polydactyly
Hypoplasia of the ulna, Thoracic hypoplasia, Metaphyseal spurs, Postaxial polydactyly, Lateral cl... OMIM:613091
Laryngotracheoesophageal Cleft Type 4
Abnormal rib morphology ORPHA:93941
Spondylometaphyseal Dysplasia, Sedaghatian Type
Delayed epiphyseal ossification, Long fibula, Narrow chest, Narrow greater sciatic notch, Short p... OMIM:250220
Kyphomelic Dysplasia
Short humerus, Short metacarpal, Radial bowing, Short femur, Anterior rib cupping, Bowed humerus,... OMIM:211350
Renpenning Syndrome
Pectus excavatum, Abnormal thumb morphology, Abnormal rib morphology, Clinodactyly of the 5th fin... ORPHA:3242
Hydrocephalus-Costovertebral Dysplasia-Sprengel Anomaly Syndrome
Sandal gap, Sprengel anomaly, Abnormal rib morphology, Brachydactyly ORPHA:2180
Congenital Osteogenesis Imperfecta-Microcephaly-Cataracts Syndrome
Abnormal rib morphology ORPHA:2772
Imperforate Oropharynx-Costovertebral Anomalies Syndrome
Clinodactyly of the 5th finger, Arachnodactyly, Abnormal rib morphology, Missing ribs ORPHA:2759
Ellis-Van Creveld Syndrome
Capitate-hamate fusion, Postaxial hand polydactyly, Pectus carinatum, Postaxial foot polydactyly,... OMIM:225500
Septopreoptic Holoprosencephaly
Abnormal rib morphology ORPHA:280195
Cog1-Cdg
Coxa valga, Rib fusion, Posterior rib gap, Flat acetabular roof, Short long bone ORPHA:263508
Phaver Syndrome
Broad hallux phalanx, Camptodactyly of finger, Short thumb, Abnormal rib morphology, Ulnar deviat... ORPHA:2876
Robinow Syndrome
Syndactyly, Brachydactyly, Bifid distal phalanx of the thumb, Missing ribs, Rib fusion, Short dis... ORPHA:97360
Male Hypergonadotropic Hypogonadism-Intellectual Disability-Skeletal Anomalies Syndrome
Abnormal rib morphology ORPHA:2234
Wolf-Hirschhorn Syndrome
Rib segmentation abnormalities, Pseudoepiphyses of the metacarpals, Short hallux, Metatarsus addu... OMIM:194190
Spondylometaphyseal Dysplasia, Sedaghatian Type
Short metacarpal, Abnormal scapula morphology, Iliac crest serration, Metaphyseal chondrodysplasi... ORPHA:93317
Short-Rib Thoracic Dysplasia 1 With Or Without Polydactyly
Hypoplasia of the ulna, Lateral clavicle hook, Early ossification of capital femoral epiphyses, C... OMIM:208500
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome
Proximal placement of thumb, Abnormal thumb morphology, Short thumb, Preaxial hand polydactyly, A... ORPHA:1120
Baller-Gerold Syndrome
Carpal bone aplasia, Hypoplasia of the ulna, Short humerus, Absent thumb, Absent radius, Aphalang... OMIM:218600
Zttk Syndrome
Cervical ribs, Rib fusion, Short foot, Small hand OMIM:617140
Spondylometaphyseal Dysplasia-Cone-Rod Dystrophy Syndrome
Ivory epiphyses, Short metacarpal, Bowing of the long bones, Metaphyseal spurs, Bowing of the leg... ORPHA:85167
Cleidocranial Dysplasia
Hypoplastic scapulae, Down-sloping shoulders, Tapered finger, Abnormal thumb morphology, Abnormal... ORPHA:1452
Cenani-Lenz Syndrome
Hypoplasia of the ulna, Finger syndactyly, Toe syndactyly, Short thumb, Hypoplasia of the radius,... ORPHA:3258
1P36 Deletion Syndrome
11 pairs of ribs, Camptodactyly of finger, Rib fusion, Short foot, Hip dysplasia, Foot polydactyl... ORPHA:1606
Cardiospondylocarpofacial Syndrome
Tarsal synostosis, Rib fusion, Cone-shaped epiphysis, Short foot, Pseudoepiphyses, Carpal synosto... OMIM:157800
Intellectual Disability-Myopathy-Short Stature-Endocrine Defect Syndrome
Clinodactyly of the 5th finger, Abnormal rib morphology, Abnormal hip bone morphology, Pectus car... ORPHA:3068
Klippel-Feil Syndrome 1, Autosomal Dominant
Sprengel anomaly, Abnormal rib morphology OMIM:118100
Mucopolysaccharidosis Type 4
Bowing of the long bones, Coxa valga, Short thorax, Abnormal rib morphology, Pectus carinatum, Ge... ORPHA:582
Holzgreve Syndrome
Hand polydactyly, Abnormal rib morphology, Abnormal morphology of ulna, Abnormal metacarpal morph... ORPHA:2167
Pyknoachondrogenesis
Hypoplastic ischia, Short iliac bones, Short thorax, Abnormal iliac wing morphology, Enlarged tho... ORPHA:3003
Antley-Bixler Syndrome
Arachnodactyly, Camptodactyly of finger, Abnormal rib morphology, Femoral bowing, Narrow pelvis b... ORPHA:83
Oculocerebrocutaneous Syndrome
Finger syndactyly, Congenital hip dislocation, Aplasia/Hypoplasia of the distal phalanges of the ... ORPHA:1647
Chromosome 1P36 Deletion Syndrome, Distal
11 pairs of ribs, Camptodactyly of finger, Metatarsus adductus, Rib fusion, Short foot, Hip dyspl... OMIM:607872
Pallister-Hall Syndrome
Mesoaxial polydactyly, Broad toe, Toe syndactyly, Overlapping toe, Radial bowing, Postaxial hand ... ORPHA:672
Campomelia, Cumming Type
Bowing of the long bones, Abnormal thorax morphology, Abnormal rib morphology, Clubbing of toes, ... ORPHA:1318
Spondyloepimetaphyseal Dysplasia, X-Linked
Pectus carinatum, Long fibula, Short palm, Short phalanx of finger, Broad metacarpals, Genu varum... OMIM:300106
Cole-Carpenter Syndrome
Crumpled long bones, Abnormal metaphysis morphology, Abnormal rib morphology, Bowing of the long ... ORPHA:2050
Poland Syndrome
Aplasia/Hypoplasia of the thumb, Finger syndactyly, Abnormal morphology of ulna, Aplasia/Hypoplas... ORPHA:2911
Bent Bone Dysplasia Syndrome 2
Bowed humerus, Ulnar bowing, Femoral bowing, Thin ribs, Short sternum, Short ribs, Hypoplastic il... OMIM:620076
Prune Belly Syndrome
Pectus excavatum, Congenital hip dislocation, Abnormal rib morphology ORPHA:2970
X-Linked Hypophosphatemia
Shortening of the talar neck, Bowing of the long bones, Bowing of the legs, Beaded ribs, Enlargem... ORPHA:89936
Trisomy 13
Postaxial hand polydactyly, Abnormal rib morphology, Abnormal pelvic girdle bone morphology, Ectr... ORPHA:3378
Brain Malformations-Musculoskeletal Abnormalities-Facial Dysmorphism-Intellectual Disability Syndrome
Arachnodactyly, Absent thumb, Rib fusion, Slender long bone, Cervical ribs ORPHA:500150
Short-Rib Thoracic Dysplasia 6 With Or Without Polydactyly
Lateral clavicle hook, Preaxial hand polydactyly, Postaxial hand polydactyly, Pectus carinatum, D... OMIM:263520
Trisomy 1Q
Toe syndactyly, Arachnodactyly, Camptodactyly of finger, Preaxial hand polydactyly, Short thorax,... ORPHA:261344
Cartilage-Hair Hypoplasia
Metaphyseal dysplasia, Bowing of the long bones, Abnormal distal phalanx morphology of finger, Fl... ORPHA:175
Craniorachischisis
Bifid sternum ORPHA:63260
Otopalatodigital Syndrome Type 2
Bowing of the long bones, Tarsal synostosis, Short hallux, Camptodactyly of finger, Short thumb, ... ORPHA:90652
Axial Mesodermal Dysplasia Spectrum
Abnormal pelvic girdle bone morphology, Abnormal rib morphology, Missing ribs ORPHA:1834
Tetraamelia-Multiple Malformations Syndrome
Aplasia/Hypoplasia involving the pelvis, Abnormal rib morphology, Missing ribs ORPHA:3301
Multiple Pterygium-Malignant Hyperthermia Syndrome
Finger syndactyly, Arachnodactyly, Camptodactyly of finger, Tapered finger, Pectus excavatum, Met... ORPHA:2215
Familial Osteodysplasia, Anderson Type
Aplastic clavicle, Missing ribs, Abnormal rib morphology, Bifid femur, Aplasia/hypoplasia of the ... ORPHA:2769
Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins
Posterior rib fusion OMIM:265380
Autosomal Dominant Popliteal Pterygium Syndrome
Finger syndactyly, Toe syndactyly, Split hand, Abnormal rib morphology ORPHA:1300
Ulna And Fibula, Absence Of, With Severe Limb Deficiency
Pectus carinatum, Femoral bowing, Foot oligodactyly, Aplasia/Hypoplasia of the tarsal bones, Phoc... OMIM:276820
Mosaic Trisomy 8
Camptodactyly of finger, Patellar aplasia, Abnormal rib morphology, Narrow pelvis bone, Narrow ch... ORPHA:96061
Radio-Renal Syndrome
Brachydactyly, Hypoplasia of the radius, Abnormal rib morphology, Short palm ORPHA:3015
Aspergillosis
Abnormal long bone morphology, Abnormal rib morphology ORPHA:1163
Fibrous Dysplasia Of Bone
Abnormal clavicle morphology, Abnormal morphology of the radius, Bowing of the long bones, Abnorm... ORPHA:249
Alagille Syndrome
Clinodactyly of the 5th finger, Hypoplasia of the ulna, Abnormal rib morphology, Short distal pha... ORPHA:52
Camptodactyly Syndrome, Guadalajara Type 3
Abnormal rib morphology, Small hand, Short foot, Thickened cortex of long bones, Broad femoral neck ORPHA:488434
Vacterl/Vater Association
Preaxial hand polydactyly, Finger syndactyly, Aplasia/Hypoplasia of the radius, Abnormal rib morp... ORPHA:887
Dextrocardia
Congenital hip dislocation, Abnormal rib morphology ORPHA:1666
Hurler Syndrome
Abnormal clavicle morphology, Camptodactyly of finger, Abnormal rib morphology, Narrow pelvis bon... ORPHA:93473
Schwartz-Jampel Syndrome
Hip contracture, Bowing of the long bones, Shoulder flexion contracture, Protrusio acetabuli, Cox... ORPHA:800
Myhre Syndrome
Brachydactyly, Abnormal rib morphology, Abnormal epiphysis morphology, Short palm, Large iliac wi... ORPHA:2588
Congenital Adrenal Hyperplasia Due To Cytochrome P450 Oxidoreductase Deficiency
Femoral bowing, Narrow chest, Short metacarpal, Abnormal metacarpal epiphysis morphology, Arachno... ORPHA:95699
Osteogenesis Imperfecta
Multiple rib fractures, Bowing of the long bones, Protrusio acetabuli, Pectus excavatum, Fracture... ORPHA:666
Ulbright-Hodes Syndrome
Short humerus, Short metacarpal, Humeroradial synostosis, Abnormal rib morphology, Hypoplasia of ... ORPHA:3404
Trisomy 18
Camptodactyly of finger, Postaxial hand polydactyly, Abnormal rib morphology, Deviation of finger... ORPHA:3380
Ear-Patella-Short Stature Syndrome
Camptodactyly of finger, Aplastic clavicle, Patellar aplasia, Abnormal rib morphology, Slender lo... ORPHA:2554
Hereditary Acrokeratotic Poikiloderma
Finger syndactyly, Camptodactyly of finger, Abnormal rib morphology, Abnormal hip bone morphology... ORPHA:2907
Monosomy 9Q22.3
Pectus excavatum, Polydactyly, Abnormal rib morphology ORPHA:77301
Autosomal Recessive Malignant Osteopetrosis
Bowing of the long bones, Abnormal rib morphology, Abnormal epiphysis morphology, Narrow chest, A... ORPHA:667
Simpson-Golabi-Behmel Syndrome
Finger syndactyly, Congenital hip dislocation, Toe syndactyly, Camptodactyly of finger, Short 2nd... ORPHA:373
Smith-Lemli-Opitz Syndrome
Finger syndactyly, Proximal placement of thumb, Postaxial hand polydactyly, Split hand, Abnormal ... ORPHA:818
Vater/Vacterl Association
Syndactyly, Absent radius, Short thumb, Hypoplasia of the radius, Preaxial polydactyly, Abnormal ... OMIM:192350
Mucopolysaccharidosis Type 3
Abnormal clavicle morphology, Avascular necrosis of the capital femoral epiphysis, Abnormal rib m... ORPHA:581
Pagod Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:991
Kindler Epidermolysis Bullosa
Finger syndactyly, Camptodactyly of finger, Abnormal rib morphology, Short 4th metacarpal, Short ... ORPHA:2908
Coffin-Lowry Syndrome
Hyperextensibility of the finger joints, Short metacarpal, Tapered finger, Pectus excavatum, Coxa... OMIM:303600
Monosomy 9P
Abnormality of the tarsal bones, Postaxial hand polydactyly, Abnormal rib morphology, Proximal pl... ORPHA:261112
Oculocerebrorenal Syndrome Of Lowe
Abnormal rib morphology, Hip dislocation, Genu valgum, Abnormal epiphysis morphology, Abnormal me... ORPHA:534
Alagille Syndrome 1
Hypoplasia of the ulna, Abnormal rib morphology, Short distal phalanx of finger OMIM:118450
Townes-Brocks Syndrome
Broad hallux phalanx, Toe syndactyly, Preaxial hand polydactyly, Partial duplication of thumb pha... ORPHA:857
Charge Syndrome
Abnormal tibia morphology, Abnormal rib morphology, Bifid femur, Clinodactyly of the 5th finger, ... ORPHA:138
Charge Syndrome
Hypoplasia of the ulna, Down-sloping shoulders, Absent radius, Short thumb, Abnormal rib morpholo... OMIM:214800

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hoxb7

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hoxb7.

No publications found that use IMPC mice or data for Hoxb7.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Hoxb7tm1e(KOMP)Wtsi Targeted, non-conditional allele ES Cells
Hoxb7tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter