Gene: Ckb


Name creatine kinase, brain

  • B-CK
  • Ck-3

Status ES CellsMice
phenotype data available

Links MGI:88407    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Ckb

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ckb data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased bone mineral content Ckbtm1.1(KOMP)Wtsi HOM Female Male postnatal 5.95E-8
decreased total body fat amount Ckbtm1.1(KOMP)Wtsi HOM Female Male postnatal 3.83E-7
increased lean body mass Ckbtm1.1(KOMP)Wtsi HOM Female Male postnatal 7.88E-7
increased lymphocyte cell number Ckbtm1.1(KOMP)Wtsi HOM Female Male postnatal 2.35E-6
increased or absent threshold for auditory brainstem response Ckbtm1.1(KOMP)Wtsi HOM Female Male postnatal 1.72E-5
abnormal vibrissa morphology Ckbtm1.1(KOMP)Wtsi HOM Female postnatal 1.85E-5
increased vertical activity Ckbtm1.1(KOMP)Wtsi HOM Female Male postnatal 2.72E-5
decreased startle reflex Ckbtm1.1(KOMP)Wtsi HOM Female Male postnatal 3.79E-5
decreased circulating cholesterol level Ckbtm1.1(KOMP)Wtsi HOM Female Male postnatal 4.25E-5

Download data as: TSV XLS


IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383) (1/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (2/2)
Diaphragm 2 No
Duodenum 2 No (2/127) (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (1/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127) (1/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (1/2)
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Quadriceps 2 No
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (1/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127)
Trachea 2 No (1/2)
Trigeminal V nerve 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vagina 2 No
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system nervous system sensory organ reproductive system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    8 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ckbtm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette)
Ckbtm1.1(KOMP)Wtsi Reporter-tagged deletion allele (post Cre, with no selection cassette)
Fixed Tissue
Ckbtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)