Gene: Cbx2

Name chromobox 2

Synonyms M33

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:88289   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Cbx2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cbx2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Cbx2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
persistence of hyaloid vascular system Cbx2tm1b(KOMP)Wtsi HET Male postnatal 1.81E-6
increased grip strength Cbx2tm1b(KOMP)Wtsi HET Female Male postnatal 7.43E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (5/393) (3/4)
Aorta 4 No (1/562)
Bone 4 No (1/539)
Brain 4 No (5/562) (4/4)
Brainstem 4 No (4/562) (4/4)
Brown adipose tissue 4 No
Cartilage tissue 4 No (1/562)
Cerebellum 4 No (4/562) (4/4)
Cerebral cortex 4 No (5/562) (4/4)
Esophagus 4 No (2/393)
Eye 4 No (1/562)
Gall bladder 4 No
Heart 4 No (3/562) (4/4)
Hippocampus 4 No (5/562) (4/4)
Hypothalamus 4 No (4/562) (4/4)
Kidney 4 No (19/562) (1/4)
Large intestine 4 No (12/562)
Liver 4 No
Lower urinary tract 4 No (3/562)
Lung 4 No (3/562)
Lymph node 4 No (1/562)
Mammary gland 4 No
Olfactory lobe 4 No (4/393) (4/4)
Oral epithelium 4 No
Ovary 4 No (1/562)
Oviduct 4 No (2/562) (2/4)
Pancreas 4 No (6/562)
Parathyroid gland 4 No (2/540)
Peripheral nervous system 4 No (3/562) (4/4)
Peyer's patch 4 No (1/393)
Pituitary gland 4 No (1/562)
Prostate gland 4 No (5/562)
Skeletal muscle 4 No
Skin 4 No (1/562)
Small intestine 4 No (11/562)
Spinal cord 4 No (3/562) (3/4)
Spleen 4 No (4/562)
Stomach 4 No (9/562)
Striatum 4 No (4/562) (4/4)
Testis 4 No (3/562) (2/4)
Thymus 4 No
Thyroid gland 4 No (16/562)
Trachea 4 No (3/562)
Uterus 4 No (2/562)
Vascular system 4 No (1/393)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    cardiovascular system
    nervous system
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/439) (4/5)
Ear 2 (2/5)
Embryo 2 (5/5)
Eye 2 (4/5)
Foot 2 (2/5)
Forebrain 2 (4/5)
Forelimb 2 (3/5)
Hand 2 (2/5)
Head 2 (4/439) (4/5)
Heart 2 (1/5)
Hindbrain 2 (5/439) (2/5)
Hindlimb 2 (3/5)
Liver 2 (1/5)
Lung 2 (1/5)
Mandibular process 2 (1/5)
Maxillary process 2 (1/5)
Midbrain 2 (4/5)
Oral cavity 2 (1/5)
Skin 2 (1/5)
Tail 2 (1/5)
Tail somite 2 (1/5)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    9 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cbx2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cbx2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene