Gene: Bmp4

Name bone morphogenetic protein 4

Synonyms
  • Bmp2b1
  • Bmp-4
  • Bmp2b
  • Bmp2b-1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:88180   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Bmp4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Bmp4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Bmp4tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
abnormal optic disc morphology Bmp4tm1b(EUCOMM)Hmgu HET Female Male postnatal 6.8E-11
abnormal iris morphology Bmp4tm1b(EUCOMM)Hmgu HET Female postnatal 3.63E-7
abnormal retina morphology Bmp4tm1b(EUCOMM)Hmgu HET Female postnatal 8.81E-6
eyelids fail to open Bmp4tm1b(EUCOMM)Hmgu HET Male postnatal 4.14E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562) (2/2)
Bone 2 No (1/539) (2/2)
Brain 2 No (5/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cecum 2 No (1/355) (2/2)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No (2/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (19/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No (1/2)
Mesenteric lymph node 2 No
Olfactory lobe 2 No (4/393) (2/2)
Oral epithelium 2 No (2/2)
Ovary 2 No (1/562)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Testis 2 No (3/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Trigeminal V nerve 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562)
Vas deferens 2 No (1/361) (1/2)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    digestive system
    cardiovascular system
    nervous system
    reproductive system
    immune system
    musculoskeletal system
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    8 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Bmp4tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Bmp4tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene