Gene: Atf4

Order

Name activating transcription factor 4

Synonyms
  • C/ATF
  • TAXREB67
  • Atf-4
  • CREB2

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:88096    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Atf4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Atf4 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Atf4tm1.1(KOMP)Mbp HET Female Male embryonic day 9.5 0.0
embryonic growth retardation Atf4tm1.1(KOMP)Mbp HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Atf4tm1.1(KOMP)Mbp HOM Female Male embryonic day 12.5 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Cartilage tissue 2 No
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Esophagus 2 No (7/415) (2/2)
Eye 2 No
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (2/2)
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    digestive system
    cardiovascular system
    nervous system
    reproductive system exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51)
Brain 4 (6/485) (2/5)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 4 (1/485) (2/5)
Embryo 4 (1/485) (2/5)
Eye 4 (1/485) (2/5)
Foot 4 (1/485)
Forebrain 4 (1/485) (2/5)
Forelimb 4 (1/485) (2/5)
Gut 2 (1/50) (2/2)
Hand 4 (1/485)
Head 4 (5/485)
Heart 4 (1/485) (2/5)
Hindbrain 4 (6/485) (2/5)
Hindlimb 4 (1/485) (2/5)
Liver 4 (1/485) (2/5)
Lung 4 (1/485)
Mandibular process 4 (1/485)
Maxillary process 4 (1/485)
Midbrain 4 (1/485) (2/5)
Nose 2 (1/51)
Oral cavity 4 (1/485)
4 (7/25) (5/5)
Skeleton 2 (1/51)
Skin 4 (1/485) (2/5)
Spinal cord 2 (1/50) (2/2)
Tail 4 (1/485) (2/5)
Tail somite 4 (1/485) (2/5)
Trachea 2 (1/50)
Urinary system 2 (1/50)


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Section
    14 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Atf4tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Atf4tm1.1(KOMP)Mbp Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene