Gene: Areg

Name amphiregulin

Synonyms
  • Sdgf
  • Mcub
  • AR

Status ES CellsMice
tm2a
Mice
tm2b
phenotype data available

Links MGI:88068   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Areg

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Areg data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased mean corpuscular volume Aregtm2b(EUCOMM)Hmgu HOM Male postnatal 4.32E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562) (1/2)
Pancreas 1 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    digestive system
    reproductive system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440)
Ear 2 (1/440)
Embryo 2 (1/440)
Eye 2 (1/440)
Foot 2
Forebrain 2 (1/440)
Forelimb 2 (1/440)
Hand 2
Head 2 (5/440)
Heart 2 (1/440)
Hindbrain 2 (5/440)
Hindlimb 2 (1/440)
Liver 2 (1/440)
Lung 2 (1/440)
Mandibular process 2 (1/440)
Maxillary process 2 (1/440)
Midbrain 2 (1/440)
Oral cavity 2 (1/440)
Skin 2 (1/440)
Tail 2 (1/440)
Tail somite 2 (1/440)


Associated Images

Associated Images
  • Echo: M-Mode Images
    32 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • Adult LacZ: LacZ Images Wholemount
    3 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Aregtm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Aregtm2b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Aregtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Aregtm191378(L1L2_Bact_P)
Vector
Gene