Gene: Apoe

Order

Name apolipoprotein E

Status ES CellsMice
em1
phenotype data available

Links MGI:88057    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Apoe

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Apoe data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased circulating cholesterol level Apoetm1Unc HOM Female Male postnatal 4.03E-21
increased circulating LDL cholesterol level Apoetm1Unc HOM Female Male postnatal 2.02E-19
increased circulating alkaline phosphatase level Apoetm1Unc HOM Female Male postnatal 8.69E-17
increased circulating triglyceride level Apoetm1Unc HOM Female Male postnatal 5.25E-12
decreased circulating glucose level Apoetm1Unc HOM Female Male postnatal 5.74E-10
increased circulating bilirubin level Apoetm1Unc HOM Female Male postnatal 1.99E-9
abnormal tooth morphology Apoetm1Unc HOM Male postnatal 2.51E-7
decreased circulating sodium level Apoetm1Unc HOM Female Male postnatal 3.36E-6
increased mean corpuscular hemoglobin concentration Apoetm1Unc HOM Female Male postnatal 1.07E-5
increased circulating free fatty acid level Apoetm1Unc HOM Female Male postnatal 3.34E-5
decreased circulating serum albumin level Apoetm1Unc HOM Female Male postnatal 4.44E-5
decreased erythrocyte cell number Apoetm1Unc HOM Female Male postnatal 4.84E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Legacy Phenotype Associated Images
Xray (199)
  • Apoetm1Unc
    HOM, Male, WTSI
  • Apoetm1Unc
    HOM, Male, WTSI
  • Apoetm1Unc
    HOM, Male, WTSI
  • Apoetm1Unc
    forelimb, WT, Male, WTSI
  • Apoetm1Unc
    forelimb, WT, Male, WTSI

show all 199 images

Tail Epidermis Wholemount (4)
  • Apoetm1Unc
    tail skin, WT, Female, WTSI
  • Apoetm1Unc
    tail skin, HET, Female, WTSI
  • Apoetm1Unc
    tail skin, WT, Female, WTSI
  • Apoetm1Unc
    tail skin, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Apoeem1(IMPC)Bay Exon Deletion
Vector
Gene
Apoetm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Apoetm213835(pL1L2_GT1_DelLacZ_bsd)
Vector
Gene