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Gene: Fabp4 MGI:88038

Registered for phenotyping at IMPC

Phenotyping is planned for a knockout strain of this gene but data is not currently available.

Gene Summary

Name:

fatty acid binding protein 4, adipocyte

Synonyms:

422/aP2, ALBP/Ap2, Ap2, Lbpl

Order Alleles

IMPC Data Collections

No Body Weight Data
No Embryo Imaging Data
No Viability Data

IMPC Phenotype Summary

Significant

Not Significant

Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Fabp4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Human diseases associated with Fabp4 (0 diseases)
Human diseases predicted to be associated with Fabp4 (396 diseases)

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Fabp4 by phenotypic similarity.

Disease	Matching phenotypes	Source
Hyperinsulinism Due To Insr Deficiency	Hypoglycemia, Insulin resistance, Fasting hyperinsulinemia, Recurrent hypoglycemia, Hyperinsuline...	ORPHA:263458
Type 2 Diabetes Mellitus	Insulin resistance, Type II diabetes mellitus	OMIM:125853
Glycogen Storage Disease Due To Glycogen Debranching Enzyme Deficiency	Hypertriglyceridemia, Hypoglycemia	ORPHA:366
Diabetes Mellitus, Transient Neonatal, 2	Transient neonatal diabetes mellitus, Type II diabetes mellitus	OMIM:610374
Hyperinsulinemic Hypoglycemia, Familial, 7	Hypoglycemia, Hyperinsulinemia, Hypoglycemic seizures, Pancreatic islet-cell hyperplasia, Hyperin...	OMIM:610021
Pancreatic Beta Cell Agenesis With Neonatal Diabetes Mellitus	Neonatal insulin-dependent diabetes mellitus	OMIM:600089
Short Stature Due To Primary Acid-Labile Subunit Deficiency	Decreased serum insulin-like growth factor 1, Insulin resistance, Delayed puberty	ORPHA:140941
Insulin Autoimmune Syndrome	Nonketotic hypoglycemia, Reactive hypoglycemia, Insulin-resistant diabetes mellitus, Insulin resi...	ORPHA:411593
Glycogen Storage Disease Vi	Hypercholesterolemia, Hyperlipidemia, Hypertriglyceridemia, Hypoglycemia	OMIM:232700
3-Hydroxy-3-Methylglutaryl-Coa Synthase Deficiency	Hypoglycemia	ORPHA:35701
Acanthosis Nigricans With Muscle Cramps And Acral Enlargement	Insulin resistance	OMIM:200170
Short Stature Due To Partial Ghr Deficiency	Decreased serum insulin-like growth factor 1, Hypoglycemia, Delayed puberty	ORPHA:314802
Hyperinsulinemic Hypoglycemia, Familial, 5	Elevated circulating insulin:C-peptide ratio, Fasting hyperinsulinemia, Hypoglycemic seizures, Hy...	OMIM:609968
Hyperinsulinemic Hypoglycemia, Familial, 3	Diabetes mellitus, Hypoglycemic seizures, Hyperinsulinemic hypoglycemia	OMIM:602485
Diabetes Mellitus, Ketosis-Prone	Beta-cell dysfunction, Insulin resistance, Diabetes mellitus	OMIM:612227
Hypoinsulinemic Hypoglycemia With Hemihypertrophy	Neonatal hypoglycemia, Hypoglycemia, Hypoinsulinemia, Fasting hypoglycemia	OMIM:240900
Glucocorticoid Deficiency 3	Recurrent hypoglycemia	OMIM:609197
Hyperinsulinemic Hypoglycemia, Familial, 2	Hypoglycemia, Pancreatic islet-cell hyperplasia, Hyperinsulinemic hypoglycemia	OMIM:601820
Body Mass Index Quantitative Trait Locus 19	Hypertriglyceridemia, Insulin resistance, Hyperlipidemia, Hyperinsulinemia, Increased serum leptin	OMIM:617885
Isolated Growth Hormone Deficiency, Type Ia	Decreased serum insulin-like growth factor 1, Hypoglycemia, Reduced circulating growth hormone co...	OMIM:262400
Short Stature Due To Ghsr Deficiency	Decreased serum insulin-like growth factor 1, Hypoglycemia, Delayed puberty	ORPHA:314811
Congenital Glucokinase-Related Hyperinsulinism	Fasting hyperinsulinemia, Recurrent hypoglycemia, Type II diabetes mellitus, Hyperinsulinemic hyp...	ORPHA:79299
Dwarfism, Low-Birth-Weight Type, With Unresponsiveness To Growth Hormone	Hypoglycemia	OMIM:223500
Hypoinsulinemic Hypoglycemia And Body Hemihypertrophy	Nonketotic hypoglycemia, Increased circulating free fatty acid level, Abnormal circulating insuli...	ORPHA:293964
Glycogen Storage Disease 0, Liver	Postprandial hyperglycemia, Neonatal hypoglycemia, Fasting hypoglycemia	OMIM:240600
Fructose And Galactose Intolerance	Hypoglycemia	OMIM:229500
Pituitary Hormone Deficiency, Combined, 4	Hypothyroidism, Hypoglycemia, Impaired growth-hormone response to insulin stimulation test, Adren...	OMIM:262700
Morbid Obesity And Spermatogenic Failure	Hypercholesterolemia, Insulin resistance, Hypertriglyceridemia, Type II diabetes mellitus	OMIM:615703
Glucocorticoid Deficiency 2	Decreased circulating cortisol level, Increased circulating ACTH level, Recurrent hypoglycemia	OMIM:607398
Hyperinsulinemic Hypoglycemia, Familial, 8	Hypoglycemia, Elevated circulating thyroid-stimulating hormone concentration, Hyperinsulinemia, H...	OMIM:620211
Cortisone Reductase Deficiency 2	Insulin resistance, Premature pubarche	OMIM:614662
Hyperinsulinemic Hypoglycemia, Familial, 4	Hypoglycemic seizures, Hyperinsulinemic hypoglycemia	OMIM:609975
Short Stature-Delayed Bone Age Due To Thyroid Hormone Metabolism Deficiency	Elevated circulating thyroid-stimulating hormone concentration, Abnormal circulating insulin conc...	ORPHA:171706
Multiple Symmetric Lipomatosis	Insulin resistance	ORPHA:2398
Hypoglycemia, Leucine-Induced	Hypoglycemia, Hyperinsulinemic hypoglycemia	OMIM:240800
Phosphoenolpyruvate Carboxykinase Deficiency, Mitochondrial	Impaired gluconeogenesis, Hypoglycemia	OMIM:261650
Lipodystrophy, Familial Partial, Type 4	Insulin-resistant diabetes mellitus, Insulin resistance, Hypertriglyceridemia	OMIM:613877
Transient Neonatal Diabetes Mellitus	Maternal diabetes, Maturity-onset diabetes of the young, Transient neonatal diabetes mellitus, Di...	ORPHA:99886
Hyperinsulinemic Hypoglycemia, Familial, 1	Pancreatic islet-cell hyperplasia, Hypoglycemic seizures, Hyperinsulinemic hypoglycemia	OMIM:256450
Long-Chain 3-Hydroxyacyl-Coa Dehydrogenase Deficiency	Hypoglycemia	OMIM:609016
Hyperproinsulinemia	Hyperglycemia, Hyperinsulinemia	OMIM:616214
Proprotein Convertase 1/3 Deficiency	Decreased circulating cortisol level, Hypogonadotropic hypogonadism, Hypoinsulinemia, Reactive hy...	OMIM:600955
Akt2-Related Familial Partial Lipodystrophy	Hypertriglyceridemia, Decreased adiponectin level, Decreased serum leptin, Insulin-resistant diab...	ORPHA:79085
Severe Early-Onset Obesity-Insulin Resistance Syndrome Due To Sh2B1 Deficiency	Hyperlipidemia, Hyperinsulinemia, Hyperglycemia	ORPHA:329249
Lipodystrophy, Congenital Generalized, Type 3	Insulin resistance, Hypercholesterolemia, Diabetes mellitus, Hypertriglyceridemia	OMIM:612526
Lipodystrophy, Familial Partial, Type 3	Hypertriglyceridemia, Maternal diabetes, Insulin resistance, Insulin-resistant diabetes mellitus,...	OMIM:604367
Obesity Due To Melanocortin 4 Receptor Deficiency	Hypertriglyceridemia, Hyperinsulinemia, Type II diabetes mellitus	ORPHA:71529
Maturity-Onset Diabetes Of The Young, Type 3	Hyperglycemia, Type II diabetes mellitus, Maturity-onset diabetes of the young	OMIM:600496
Maturity-Onset Diabetes Of The Young, Type 10	Diabetic ketoacidosis, Hyperglycemia, Diabetes mellitus, Maturity-onset diabetes of the young	OMIM:613370
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency	Hyperlipidemia, Hypoglycemia	ORPHA:364
Familial Partial Lipodystrophy, Köbberling Type	Insulin resistance, Diabetes mellitus, Hyperinsulinemia	ORPHA:79084
Homozygous 11P15-P14 Deletion Syndrome	Hyperinsulinemia, Hypoglycemia	OMIM:606528
Hyperinsulinism-Hyperammonemia Syndrome	Hyperinsulinemic hypoglycemia, Fasting hyperinsulinemia, Reactive hypoglycemia	ORPHA:35878
Glycogen Storage Disease Ixa1	Hypercholesterolemia, Hypertriglyceridemia, Hypoglycemia	OMIM:306000
Insulinomatosis And Diabetes Mellitus	Impaired glucose tolerance, Insulinoma, Multiple pancreatic beta-cell adenomas, Type II diabetes ...	OMIM:147630
3-Methylglutaconic Aciduria Type 1	Hypoglycemia	ORPHA:67046
Hyperinsulinism Due To Hnf1A Deficiency	Ketotic hypoglycemia, Maternal diabetes, Reactive hypoglycemia, Maturity-onset diabetes of the yo...	ORPHA:324575
Mitochondrial Complex Iii Deficiency, Nuclear Type 3	Hypoglycemia	OMIM:615158
Microcephalic Primordial Dwarfism-Insulin Resistance Syndrome	Primary gonadal insufficiency, Insulin-resistant diabetes mellitus, Hypertriglyceridemia	ORPHA:436182
Glucocorticoid Resistance, Generalized	Hypoglycemia, Increased circulating ACTH level, Increased circulating cortisol level, Increased s...	OMIM:615962
Hypertriglyceridemia 1	Glucose intolerance, Hypopituitarism, Hypertriglyceridemia	OMIM:145750
Pituitary Hormone Deficiency, Combined, 2	Decreased thyroid-stimulating hormone level, Reduced circulating prolactin concentration, Abnorma...	OMIM:262600
Coronary Artery Disease, Autosomal Dominant 2	Glucose intolerance, Hypertriglyceridemia, Impaired glucose tolerance, Type II diabetes mellitus	OMIM:610947
Acth Deficiency, Isolated	Decreased circulating cortisol level, Adrenal hypoplasia, Adrenocorticotropic hormone deficiency,...	OMIM:201400
Lipodystrophy, Familial Partial, Type 6	Insulin resistance, Hyperlipidemia, Diabetes mellitus	OMIM:615980
Glucocorticoid Deficiency 1	Decreased circulating cortisol level, Abnormal circulating renin, Increased circulating ACTH leve...	OMIM:202200
Mody	Transient neonatal diabetes mellitus, Insulin-resistant diabetes mellitus, Abnormal circulating i...	ORPHA:552
Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities	Hypoglycemia, Precocious puberty, Insulin-resistant diabetes mellitus, Hyperinsulinemia, Diabetic...	OMIM:262190
Hyperinsulinemic Hypoglycemia, Familial, 6	Abnormality of the pancreatic islet cells, Hypoglycemic seizures, Hyperinsulinemic hypoglycemia	OMIM:606762
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency	Postprandial hyperglycemia, Hyperlipidemia, Ketotic hypoglycemia, Glycosuria	ORPHA:2089
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome	Reactive hypoglycemia, Hyperinsulinemia, Pancreatic islet-cell hyperplasia, Fasting hypoglycemia,...	ORPHA:276608
Polyendocrine-Polyneuropathy Syndrome	Hypogonadotropic hypogonadism, Hypoglycemia, Anterior pituitary hypoplasia, Decreased circulating...	ORPHA:453533
Familial Renal Glucosuria	Insulin resistance, Abnormal circulating insulin concentration, Glycosuria, Hyperglycemia, Abnorm...	ORPHA:69076
Lipase Deficiency, Combined	Hypertriglyceridemia, Type II diabetes mellitus	OMIM:246650
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency	Excessive insulin response to glucagon test, Maternal diabetes, Hyperinsulinemia, Hypoglycemic se...	ORPHA:276580
Glucocorticoid Deficiency 4 With Or Without Mineralocorticoid Deficiency	Decreased circulating cortisol level, Hypoglycemia, Precocious puberty, Abnormal circulating reni...	OMIM:614736
Plin1-Related Familial Partial Lipodystrophy	Insulin-resistant diabetes mellitus at puberty, Hypertriglyceridemia, Hyperinsulinemia, Abnormal ...	ORPHA:280356
Autosomal Recessive Hyperinsulinism Due To Kir6.2 Deficiency	Elevated circulating growth hormone concentration, Abnormal response to glucagon stimulation test...	ORPHA:79644
Neonatal Hemochromatosis	Hypoglycemia	ORPHA:446
Lipe-Related Familial Partial Lipodystrophy	Hypertriglyceridemia, Decreased adiponectin level, Decreased serum leptin, Insulin-resistant diab...	ORPHA:435660
Glycogen Storage Disease Iii	Hyperlipidemia, Hypoglycemia	OMIM:232400
Pituitary Hormone Deficiency, Combined, 6	Decreased thyroid-stimulating hormone level, Ectopic posterior pituitary, Hypoglycemia, Decreased...	OMIM:613986
Pyridoxamine 5-Prime-Phosphate Oxidase Deficiency	Hypoglycemia	OMIM:610090
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies	Glucose intolerance, Hyperglycemia, Hypergonadotropic hypogonadism, Male hypogonadism	OMIM:307500
Acquired Partial Lipodystrophy	Insulin resistance	ORPHA:79087
Acanthosis Nigricans-Insulin Resistance-Muscle Cramps-Acral Enlargement Syndrome	Insulin-resistant diabetes mellitus, Insulin resistance, Elevated circulating growth hormone conc...	ORPHA:90301
Endocardial Fibroelastosis	Anterior hypopituitarism, Hypoglycemia	ORPHA:2022
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency	Excessive insulin response to glucagon test, Hyperinsulinemia, Hypoglycemic seizures, Fasting hyp...	ORPHA:276575
Glycogen Storage Disease Ixc	Hypertriglyceridemia, Hypoglycemia, Fasting hypoglycemia	OMIM:613027
Dicarboxylic Aminoaciduria	Fasting hypoglycemia	OMIM:222730
Severe Neurodegenerative Syndrome With Lipodystrophy	Insulin resistance, Hypertriglyceridemia, Hyperinsulinemia	ORPHA:363400
Obesity Due To Congenital Leptin Deficiency	Hypertriglyceridemia, Hypergonadotropic hypogonadism, Decreased serum leptin, Insulin-resistant d...	ORPHA:66628
Combined Oxidative Phosphorylation Deficiency 41	Decreased circulating cortisol level, Hypoglycemia	OMIM:618838
Mandibuloacral Dysplasia	Hypertriglyceridemia, Increased circulating free fatty acid level, Insulin resistance, Insulin-re...	ORPHA:2457
Hyperinsulinism Due To Ucp2 Deficiency	Reactive hypoglycemia, Hypoglycemic seizures, Recurrent hypoglycemia, Hyperinsulinemic hypoglycem...	ORPHA:276556
Mitochondrial Complex Iii Deficiency, Nuclear Type 9	Hypoglycemia	OMIM:616111
Obesity Due To Leptin Receptor Gene Deficiency	Hypertriglyceridemia, Hypergonadotropic hypogonadism, Decreased serum leptin, Insulin-resistant d...	ORPHA:179494
Orthostatic Hypotension 2	Hypoglycemia	OMIM:618182
Glycogen Storage Disease Due To Liver Glycogen Phosphorylase Deficiency	Hyperlipidemia, Hypoglycemia, Delayed puberty	ORPHA:369
3-Methylcrotonyl-Coa Carboxylase Deficiency	Hypoglycemia	ORPHA:6
Diarrhea 13	Recurrent hypoglycemia	OMIM:620357
Mandibular Hypoplasia, Deafness, Progeroid Features, And Lipodystrophy Syndrome	Diabetes mellitus, Insulin resistance, Hypertriglyceridemia, Male hypogonadism	OMIM:615381
Congenital Isolated Acth Deficiency	Decreased circulating cortisol level, Adrenal hypoplasia, Hypoglycemic seizures, Adrenocorticotro...	ORPHA:199296
Propionic Acidemia	Hypoglycemia	ORPHA:35
Monocarboxylate Transporter 1 Deficiency	Ketotic hypoglycemia	OMIM:616095
Combined Oxidative Phosphorylation Deficiency 34	Primary adrenal insufficiency, Elevated circulating thyroid-stimulating hormone concentration, Hy...	OMIM:617872
Congenital Generalized Lipodystrophy	Diabetes mellitus, Hypertriglyceridemia, Precocious puberty in females, Insulin resistance, Hyper...	ORPHA:528
Isobutyryl-Coa Dehydrogenase Deficiency	Ketotic hypoglycemia	ORPHA:79159
Silver-Russell Syndrome Due To Maternal Uniparental Disomy Of Chromosome 11	Hypoglycemia	ORPHA:231147
Riboflavin Deficiency	Hypoglycemia	OMIM:615026
Insulinoma	Nonketotic hypoglycemia, Reactive hypoglycemia, Abnormality of the pancreatic islet cells, Fastin...	ORPHA:97279
Intellectual Developmental Disorder With Macrocephaly, Seizures, And Speech Delay	Recurrent hypoglycemia	OMIM:618158
Laron Syndrome	Abnormality of the endocrine system, Hypercholesterolemia, Hypoglycemia, Delayed puberty	ORPHA:633
Seckel Syndrome 10	Diabetes mellitus, Hypertriglyceridemia, Impaired glucose tolerance, Elevated circulating luteini...	OMIM:617253
Galactokinase Deficiency	Hypercholesterolemia, Hyperinsulinemia, Hypoglycemia, Hypergonadotropic hypogonadism	ORPHA:79237
Ornithine Transcarbamylase Deficiency	Hypoglycemia	ORPHA:664
Carnitine Palmitoyl Transferase 1A Deficiency	Hypoglycemia, Transient hyperlipidemia	ORPHA:156
Blue Diaper Syndrome	Decreased circulating T4 concentration, Recurrent hypoglycemia, Elevated circulating thyroid-stim...	ORPHA:94086
Mitochondrial Pyruvate Carrier Deficiency	Hypoglycemia	OMIM:614741
3-Methylglutaconic Aciduria Type 4	Hypoglycemia	ORPHA:67048
Mehmo Syndrome	Male hypogonadism, Hypoglycemia, Decreased response to growth hormone stimulation test, Delayed p...	OMIM:300148
Post-Traumatic Pituitary Deficiency	Hypoglycemia, Decreased response to growth hormone stimulation test, Hypogonadotropic hypogonadis...	ORPHA:95619
Lipodystrophy, Familial Partial, Type 1	Insulin-resistant diabetes mellitus, Hypertriglyceridemia, Hyperglycemia	OMIM:608600
Adrenal Hyperplasia, Congenital, Due To 21-Hydroxylase Deficiency	Adrenal hyperplasia, Hypoglycemia, Adrenogenital syndrome	OMIM:201910
Silver-Russell Syndrome Due To An Imprinting Defect Of 11P15	Hypoglycemia, Neonatal hypoglycemia	ORPHA:231140
Pparg-Related Familial Partial Lipodystrophy	Diabetes mellitus, Hypertriglyceridemia, Maternal diabetes, Insulin-resistant diabetes mellitus, ...	ORPHA:79083
2-Methylbutyryl-Coa Dehydrogenase Deficiency	Hypoglycemia	OMIM:610006
2P21 Microdeletion Syndrome	Hypogonadism, Hypoglycemia	ORPHA:163693
Insulin-Resistance Syndrome Type B	Abnormal circulating leptin concentration, Insulin resistance, Fasting hyperinsulinemia, Insulin-...	ORPHA:2298
Body Mass Index Quantitative Trait Locus 20	Hyperinsulinemia	OMIM:618406
Familial Partial Lipodystrophy, Dunnigan Type	Diabetes mellitus, Insulin resistance, Hypertriglyceridemia	ORPHA:2348
Obesity Due To Prohormone Convertase I Deficiency	Decreased response to growth hormone stimulation test, Gonadotropin deficiency, Hyperinsulinemia,...	ORPHA:71528
Obesity Due To Pro-Opiomelanocortin Deficiency	Decreased response to growth hormone stimulation test, Gonadotropin deficiency, Hyperinsulinemia,...	ORPHA:71526
Dihydrolipoamide Dehydrogenase Deficiency	Hypoglycemia	OMIM:246900
Glycogen Storage Disease Ixb	Hypoglycemia	OMIM:261750
Familial Multiple Lipomatosis	Insulin resistance, Hyperlipidemia	ORPHA:199276
Placental Insufficiency	Insulin resistance	ORPHA:439167
Hypoadrenocorticism, Familial	Hypoglycemia, Adrenal hypoplasia, Adrenal insufficiency	OMIM:240200
Mitochondrial Complex Iii Deficiency, Nuclear Type 11	Hypoglycemia	OMIM:620137
Acquired Generalized Lipodystrophy	Insulin-resistant diabetes mellitus, Insulin resistance, Hypertriglyceridemia, Hyperinsulinemia	ORPHA:79086
Obesity And Hypopigmentation	Hyperinsulinemia	OMIM:620195
Short Chain Acyl-Coa Dehydrogenase Deficiency	Ketotic hypoglycemia	ORPHA:26792
Mitochondrial Complex Iv Deficiency, Nuclear Type 4	Hypoglycemia	OMIM:619048
Combined Oxidative Phosphorylation Deficiency 40	Decreased circulating cortisol level, Hypoglycemia	OMIM:618835
Combined Oxidative Phosphorylation Deficiency 42	Decreased circulating cortisol level, Hypoglycemia	OMIM:618839
Combined Oxidative Phosphorylation Deficiency 36	Hypoglycemia	OMIM:617950
Bangstad Syndrome	Abnormality of the parathyroid gland, Hyperinsulinemia, Increased circulating cortisol level, Pri...	ORPHA:1227
Mitochondrial Complex I Deficiency, Nuclear Type 19	Hypoglycemia	OMIM:618241
Polyendocrine-Polyneuropathy Syndrome	Hypoglycemia, Anterior pituitary hypoplasia, Hypogonadotropic hypogonadism, Central hypothyroidis...	OMIM:616113
Congenital Cataracts-Facial Dysmorphism-Neuropathy Syndrome	Hypoglycemia, Hypogonadotropic hypogonadism	ORPHA:48431
Bdv Syndrome	Decreased thyroid-stimulating hormone level, Hypogonadotropic hypogonadism, Hyperinsulinemia, Cen...	OMIM:619326
Microcephaly, Short Stature, And Impaired Glucose Metabolism 1	Diabetes mellitus, Delayed thelarche, Delayed puberty, Hyperinsulinemic hypoglycemia	OMIM:616033
Hsd10 Mitochondrial Disease	Hypoglycemia	OMIM:300438
Combined Malonic And Methylmalonic Acidemia	Hypoglycemia	ORPHA:289504
Reni Syndrome	Hypertriglyceridemia, Hypoglycemia, Hypogonadism, Adrenal insufficiency, Hypothyroidism	OMIM:617575
Pyruvate Carboxylase Deficiency	Hypoglycemia	OMIM:266150
Solitary Fibrous Tumor	Recurrent hypoglycemia, Hypoglycemia, Hypoinsulinemia	ORPHA:2126
Pituitary Stalk Interruption Syndrome	Ectopic posterior pituitary, Hypoglycemia, Adrenal hypoplasia, Hypothyroidism, Delayed puberty, A...	ORPHA:95496
Histidinuria-Renal Tubular Defect Syndrome	Hypoglycemia	ORPHA:2158
Multiple Endocrine Neoplasia, Type I	Hypoglycemia, Pancreatic islet cell adenoma, Elevated circulating growth hormone concentration, P...	OMIM:131100
Combined Oxidative Phosphorylation Deficiency 52	Hypoglycemia, Adrenal insufficiency	OMIM:619386
Pyridoxine-Dependent Epilepsy	Hypoglycemia	ORPHA:3006
Hemochromatosis, Neonatal	Hypoglycemia	OMIM:231100
Mitochondrial Complex Iii Deficiency, Nuclear Type 5	Hypoglycemia	OMIM:615160
Combined Oxidative Phosphorylation Deficiency 47	Hypoglycemia	OMIM:618958
Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency	Hypogonadism, Insulin resistance, Hypoglycemia	ORPHA:73272
Estrogen Resistance	Increased circulating osteocalcin level, Impaired glucose tolerance, Hyperinsulinemia, Increased ...	OMIM:615363
Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic	Impaired gluconeogenesis, Hypoglycemia, Fasting hypoglycemia	OMIM:261680
Mitochondrial Complex V (Atp Synthase) Deficiency, Nuclear Type 5	Hypoglycemia	OMIM:618120
Glycogen Storage Disease Ixd	Hypoglycemia	OMIM:300559
Diabetes Mellitus, Transient Neonatal, 3	Transient neonatal diabetes mellitus, Hyperglycemia, Maternal diabetes	OMIM:610582
Obesity Due To Sim1 Deficiency	Glucose intolerance, Hyperinsulinemia	ORPHA:369873
Carnitine Palmitoyltransferase I Deficiency	Transient hyperlipidemia, Hypoketotic hypoglycemia	OMIM:255120
Temple Syndrome	Precocious puberty, Recurrent hypoglycemia, Type II diabetes mellitus, Decreased response to grow...	ORPHA:254516
Congenital Hyperinsulinism Due To Hnf4A Deficiency	Hyperinsulinemia, Pancreatic islet-cell hyperplasia, Fasting hypoglycemia, Glycosuria, Hyperinsul...	ORPHA:263455
Cerebrooculofacioskeletal Syndrome 1	Insulin resistance	OMIM:214150
Cidec-Related Familial Partial Lipodystrophy	Insulin-resistant diabetes mellitus, Hypertriglyceridemia, Decreased adiponectin level, Decreased...	ORPHA:435651
Silver-Russell Syndrome 2	Neonatal hypoglycemia	OMIM:618905
Hyperinsulinism Due To Short Chain 3-Hydroxylacyl-Coa Dehydrogenase Deficiency	Increased circulating free fatty acid level, Fasting hyperinsulinemia, Hypoglycemic seizures, Hyp...	ORPHA:71212
Rabson-Mendenhall Syndrome	Increased pineal volume, Impaired glucose tolerance, Precocious puberty, Insulin resistance, Fast...	ORPHA:769
Silver-Russell Syndrome Due To 7P11.2P13 Microduplication	Hypoglycemia	ORPHA:231137
Fanconi-Bickel Syndrome	Diabetes mellitus, Hypertriglyceridemia, Impaired glucose tolerance, Fasting hypoglycemia, Glycos...	ORPHA:2088
Mandibuloacral Dysplasia With Type B Lipodystrophy	Insulin resistance, Hyperlipidemia, Delayed puberty	ORPHA:90154
Malonyl-Coa Decarboxylase Deficiency	Hypoglycemia	OMIM:248360
Infantile Liver Failure Syndrome 2	Hypoglycemia	OMIM:616483
Acth-Independent Macronodular Adrenal Hyperplasia 2	Increased urinary cortisol level, Decreased circulating ACTH concentration, Increased circulating...	OMIM:615954
Lipodystrophy, Congenital Generalized, Type 4	Insulin resistance, Hypertriglyceridemia, Hyperinsulinemia	OMIM:613327
Tenorio Syndrome	Hypoglycemia, Hypoinsulinemia	OMIM:616260
Long Chain 3-Hydroxyacyl-Coa Dehydrogenase Deficiency	Hypoglycemia, Hypoketotic hypoglycemia	ORPHA:5
Dopamine Beta-Hydroxylase Deficiency	Insulin resistance, Hyperinsulinemia, Hypoglycemia	ORPHA:230
Short Syndrome	Insulin resistance, Glucose intolerance, Hyperglycemia, Insulin-resistant diabetes mellitus	OMIM:269880
Generalized Glucocorticoid Resistance Syndrome	Increased urinary cortisol level, Adrenal hyperplasia, Hypoglycemia, Precocious puberty, Increase...	ORPHA:786
Congenital Adrenal Hyperplasia Due To 3-Beta-Hydroxysteroid Dehydrogenase Deficiency	Decreased circulating cortisol level, Increased circulating androstenedione concentration, Congen...	ORPHA:90791
Congenital Lipoid Adrenal Hyperplasia Due To Star Deficency	Decreased circulating cortisol level, Adrenal hyperplasia, Hypoglycemia, Increased circulating AC...	ORPHA:90790
Pyridoxal Phosphate-Responsive Seizures	Hypoglycemia	ORPHA:79096
3-Methylglutaconic Aciduria With Deafness, Encephalopathy, And Leigh-Like Syndrome	Hypoglycemia	OMIM:614739
Pyruvate Dehydrogenase E3 Deficiency	Hypoglycemia	ORPHA:2394
Combined Oxidative Phosphorylation Deficiency 10	Hypoglycemia	OMIM:614702
Abdominal Obesity-Metabolic Syndrome 3	Hypercholesterolemia, Hyperglycemia, Hypertriglyceridemia, Type II diabetes mellitus	OMIM:615812
Mandibuloacral Dysplasia With Type A Lipodystrophy	Insulin resistance, Hyperlipidemia	ORPHA:90153
Aromatase Deficiency	Insulin resistance, Hyperlipidemia, Hypergonadotropic hypogonadism, Type II diabetes mellitus	ORPHA:91
Cataract-Growth Hormone Deficiency-Sensory Neuropathy-Sensorineural Hearing Loss-Skeletal Dysplasia Syndrome	Decreased response to growth hormone stimulation test, Fasting hypoglycemia	ORPHA:436174
Autosomal Semi-Dominant Severe Lipodystrophic Laminopathy	Diabetes mellitus, Hypertriglyceridemia, Decreased adiponectin level, Decreased serum leptin, Ins...	ORPHA:280365
Familial Glucocorticoid Deficiency	Decreased circulating dehydroepiandrosterone concentration, Decreased circulating cortisol level,...	ORPHA:361
Glycogen Storage Disease Ia	Hypoglycemia, Hyperlipidemia, Xanthelasma, Fasting hypoglycemia, Delayed puberty	OMIM:232200
Retinitis Pigmentosa	Hypogonadism, Hyperinsulinemia, Type II diabetes mellitus	ORPHA:791
Classic Galactosemia	Decreased serum insulin-like growth factor 1, Hypoglycemia, Delayed puberty	ORPHA:79239
Acyl-Coa Dehydrogenase, Medium-Chain, Deficiency Of	Hypoglycemia	OMIM:201450
Pituitary Apoplexy	Hypoglycemia, Decreased response to growth hormone stimulation test, Reduced circulating prolacti...	ORPHA:95613
Immunodeficiency, Common Variable, 10	Central adrenal insufficiency, Abnormal response to ACTH stimulation test, Hypoglycemia, Decrease...	OMIM:615577
Silver-Russell Syndrome	Insulin resistance, Premature adrenarche, Recurrent hypoglycemia, Precocious puberty	ORPHA:813
Congenital Disorder Of Glycosylation, Type Im	Hypoketotic hypoglycemia, Increased circulating free fatty acid level	OMIM:610768
Fanconi Renotubular Syndrome 4 With Maturity-Onset Diabetes Of The Young	Diabetes mellitus, Hypoglycemia, Glycosuria	OMIM:616026
Carnitine Palmitoyltransferase Ii Deficiency, Infantile	Hypoketotic hypoglycemia	OMIM:600649
Donohue Syndrome	Precocious puberty, Hyperinsulinemia, Pancreatic islet-cell hyperplasia, Fasting hypoglycemia, Po...	OMIM:246200
Short Fifth Metacarpals-Insulin Resistance Syndrome	Hyperinsulinemia	ORPHA:66518
Mitochondrial Dna Depletion Syndrome 9 (Encephalomyopathic Type With Methylmalonic Aciduria)	Hypoglycemia	OMIM:245400
3-Hydroxyacyl-Coa Dehydrogenase Deficiency	Hypoglycemic seizures, Hypoketotic hypoglycemia	OMIM:231530
Maple Syrup Urine Disease	Hypoglycemia	OMIM:248600
Houge-Janssens Syndrome 1	Hypoglycemia	OMIM:616355
Primary Microcephaly-Mild Intellectual Disability-Young-Onset Diabetes Syndrome	Hypothyroidism, Diabetes mellitus, Hypoglycemia, Delayed puberty	ORPHA:391408
Short Syndrome	Insulin resistance, Diabetes mellitus	ORPHA:3163
Late-Onset Isolated Acth Deficiency	Hypoparathyroidism, Decreased circulating cortisol level, Hypoglycemia, Pituitary adenoma, Decrea...	ORPHA:199299
Retinitis Pigmentosa-Intellectual Disability-Deafness-Hypogonadism Syndrome	Hypergonadotropic hypogonadism, Hyperinsulinemia, Type II diabetes mellitus	ORPHA:3085
Cog8-Cdg	Hypoglycemia	ORPHA:95428
Estrogen Resistance Syndrome	Increased circulating gonadotropin level, Absence of secondary sex characteristics, Hyperinsuline...	ORPHA:785
Thalidomide Embryopathy	Insulin resistance	ORPHA:3312
Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency	Hypertriglyceridemia, Hypoglycemia, Fasting hypoglycemia, Delayed puberty, Hypercholesterolemia	ORPHA:264580
Mitochondrial Complex I Deficiency, Nuclear Type 33	Hypoglycemia	OMIM:618253
Medium Chain Acyl-Coa Dehydrogenase Deficiency	Hypoglycemia	ORPHA:42
Leprechaunism	Insulin resistance, Hyperinsulinemia, Central hypothyroidism, Hyperaldosteronism, Recurrent infan...	ORPHA:508
Glycogen Storage Disease Due To Liver And Muscle Phosphorylase Kinase Deficiency	Hypertriglyceridemia, Ketotic hypoglycemia, Recurrent hypoglycemia, Fasting hypoglycemia, Hyperch...	ORPHA:79240
Mitochondrial Complex Iii Deficiency, Nuclear Type 6	Hyperglycemia, Hypoglycemia	OMIM:615453
Carnitine Deficiency, Systemic Primary	Impaired gluconeogenesis, Recurrent hypoglycemia	OMIM:212140
Aica-Ribosuria Due To Atic Deficiency	Hypoglycemia	OMIM:608688
Timothy Syndrome	Hypothyroidism, Hypoglycemia	OMIM:601005
Sheehan Syndrome	Decreased circulating cortisol level, Hypoglycemia, Reduced circulating prolactin concentration, ...	ORPHA:91355
Mandibuloacral Dysplasia With Type B Lipodystrophy	Hyperlipidemia, Insulin-resistant diabetes mellitus, Hyperinsulinemia, Glucose intolerance, Hyper...	OMIM:608612
Fructose-1,6-Bisphosphatase Deficiency	Hypoglycemia	OMIM:229700
Hypotonia-Cystinuria Syndrome	Hypergonadotropic hypogonadism, Decreased response to growth hormone stimulation test, Neonatal h...	OMIM:606407
Neurodevelopmental Disorder, Mitochondrial, With Abnormal Movements And Lactic Acidosis, With Or Without Seizures	Hypoglycemia	OMIM:617710
Carnitine-Acylcarnitine Translocase Deficiency	Hypoglycemia, Neonatal hypoglycemia	OMIM:212138
Mitochondrial Complex Iv Deficiency, Nuclear Type 3	Neonatal hypoglycemia	OMIM:619046
3-Methylcrotonyl-Coa Carboxylase 1 Deficiency	Hypoglycemia	OMIM:210200
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency	Hypoglycemia	OMIM:246450
Werner Syndrome	Hypogonadism, Insulin resistance, Thyroid carcinoma, Type II diabetes mellitus	ORPHA:902
Microcephaly, Short Stature, And Impaired Glucose Metabolism 2	Recurrent hypoglycemia, Hypothyroidism, Delayed puberty	OMIM:616817
Hsd10 Disease, Infantile Type	Hypoglycemia	ORPHA:391428
Lipodystrophy, Familial Partial, Type 2	Hypertriglyceridemia, Insulin-resistant diabetes mellitus, Hyperinsulinemia, Type II diabetes mel...	OMIM:151660
Fructose-1,6-Bisphosphatase Deficiency	Fasting hypoglycemia, Hypoglycemia, Neonatal hypoglycemia	ORPHA:348
Marbach-Rustad Progeroid Syndrome	Insulin resistance	OMIM:619322
Cholestasis, Progressive Familial Intrahepatic, 5	Hypoglycemia	OMIM:617049
Mitochondrial Complex I Deficiency, Nuclear Type 20	Hypoglycemia	OMIM:611126
Propionic Acidemia	Hypoglycemia	OMIM:606054
Smith-Kingsmore Syndrome	Hypoglycemia	OMIM:616638
Short Stature, Microcephaly, And Endocrine Dysfunction	Insulin resistance, Diabetes mellitus, Hypothyroidism	OMIM:616541
Silver-Russell Syndrome Due To A Point Mutation	Hypothyroidism, Hypoglycemia	ORPHA:397590
Basilicata-Akhtar Syndrome	Precocious puberty, Neonatal hypoglycemia	OMIM:301032
Bachmann-Bupp Syndrome	Hypoglycemia	OMIM:619075
Glycogen Storage Disease Ib	Xanthelasma, Hyperlipidemia, Hypoglycemia, Delayed puberty	OMIM:232220
Whipple Disease	Insulin resistance, Hypothyroidism	ORPHA:3452
Silver-Russell Syndrome 1	Decreased response to growth hormone stimulation test, Fasting hypoglycemia	OMIM:180860
Monosomy 13Q34	Insulin resistance	ORPHA:96168
Perlman Syndrome	Hyperinsulinemia	ORPHA:2849
Glycerol Kinase Deficiency	Adrenocortical hypoplasia, Hypertriglyceridemia, Hypoglycemia, Adrenal insufficiency	OMIM:307030
Mitochondrial Complex Iv Deficiency, Nuclear Type 23	Hypoglycemia	OMIM:620275
Acute Adrenal Insufficiency	Decreased circulating cortisol level, Hypoglycemia, Adrenal hypoplasia, Primary adrenal insuffici...	ORPHA:95409
Methylmalonic Aciduria Due To Methylmalonyl-Coa Mutase Deficiency	Hypoglycemia	OMIM:251000
Addison Disease	Hypoparathyroidism, Decreased circulating cortisol level, Hypoglycemia, Adrenal calcification, Ad...	ORPHA:85138
Intellectual Developmental Disorder, Autosomal Dominant 45	Neonatal hypoglycemia	OMIM:617600
Silver-Russell Syndrome Due To Maternal Uniparental Disomy Of Chromosome 7	Decreased response to growth hormone stimulation test, Precocious puberty, Insulin resistance, Fa...	ORPHA:96182
Multiple Endocrine Neoplasia Type 4	Hyperparathyroidism, Pituitary corticotropic cell adenoma, Fasting hyperinsulinemia, Elevated cir...	ORPHA:276152
Mitochondrial Trifunctional Protein Deficiency 2	Hypoglycemia	OMIM:620300
Hypothyroidism Due To Deficient Transcription Factors Involved In Pituitary Development Or Function	Decreased thyroid-stimulating hormone level, Ectopic posterior pituitary, Hypoglycemia, Anterior ...	ORPHA:226307
Deficiency In Anterior Pituitary Function-Variable Immunodeficiency Syndrome	Decreased circulating cortisol level, Decreased serum insulin-like growth factor 1, Decreased res...	ORPHA:293978
D-Glyceric Aciduria	Hypoglycemia	OMIM:220120
Alstrom Syndrome	Hypertriglyceridemia, Hypergonadotropic hypogonadism, Decreased response to growth hormone stimul...	OMIM:203800
Glutaric Acidemia I	Hypoglycemia	OMIM:231670
Shashi-Pena Syndrome	Hypoglycemia	OMIM:617190
X-Linked Acrogigantism	Decreased thyroid-stimulating hormone level, Enlarged pituitary gland, Diabetes insipidus, Elevat...	ORPHA:300373
Gitelman Syndrome	Maternal diabetes, Insulin resistance, Delayed puberty, Parathyroid adenoma, Glucose intolerance,...	ORPHA:358
Glycogen Storage Disease Ic	Xanthelasma, Hyperlipidemia, Hypoglycemia, Delayed puberty	OMIM:232240
Multiple Acyl-Coa Dehydrogenase Deficiency	Hypoglycemia, Glycosuria	OMIM:231680
Inherited Isolated Adrenal Insufficiency Due To Partial Cyp11A1 Deficiency	Decreased circulating cortisol level, Adrenal calcification, Adrenal hypoplasia, Elevated circula...	ORPHA:289548
Very Long Chain Acyl-Coa Dehydrogenase Deficiency	Hypoketotic hypoglycemia, Increased circulating free fatty acid level	ORPHA:26793
Mandibuloacral Dysplasia With Type A Lipodystrophy	Impaired glucose tolerance, Hyperlipidemia, Insulin-resistant diabetes mellitus, Hyperinsulinemia...	OMIM:248370
Orthostatic Hypotension 1	Neonatal hypoglycemia, Reduced circulating prolactin concentration	OMIM:223360
46,Xy Difference Of Sex Development-Adrenal Insufficiency Due To Cyp11A1 Deficiency	Decreased circulating cortisol level, Adrenal hypoplasia, Elevated circulating luteinizing hormon...	ORPHA:168558
Congenital Disorder Of Glycosylation, Type Ib	Hyperinsulinemic hypoglycemia, Steatorrhea	OMIM:602579
Bardet-Biedl Syndrome 1	Nephrogenic diabetes insipidus, Insulin resistance, Diabetes mellitus, Hypogonadism	OMIM:209900
Lipodystrophy, Familial Partial, Type 7	Hypertriglyceridemia, Impaired glucose tolerance, Insulin resistance, Glucose intolerance, Type I...	OMIM:606721
Carnitine Palmitoyltransferase Ii Deficiency	Hyperlipidemia, Hypoketotic hypoglycemia	ORPHA:157
Woodhouse-Sakati Syndrome	Streak ovary, Decreased response to growth hormone stimulation test, Insulin-resistant diabetes m...	ORPHA:3464
Beta-Ketothiolase Deficiency	Hyperglycemia, Hypoglycemia	ORPHA:134
Recurrent Metabolic Encephalomyopathic Crises-Rhabdomyolysis-Cardiac Arrhythmia-Intellectual Disability Syndrome	Compensated hypothyroidism, Hypoglycemia, Hypoglycemic seizures	ORPHA:480864
Mitochondrial Complex Iv Deficiency, Nuclear Type 22	Hypoglycemia	OMIM:619355
Mirage Syndrome	Hypergonadotropic hypogonadism, Hypoglycemia, Adrenal hypoplasia, Adrenal insufficiency	OMIM:617053
Mitochondrial Complex Iv Deficiency, Nuclear Type 12	Hypoglycemia, Neonatal hypoglycemia	OMIM:619055
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency Type Ib	Hypertriglyceridemia, Hypoglycemia, Hyperlipidemia, Thyroiditis, Hypoglycemic seizures, Xanthelas...	ORPHA:79259
Congenital Disorder Of Glycosylation, Type Ig	Hypoglycemia	OMIM:607143
Acyl-Coa Dehydrogenase, Very Long-Chain, Deficiency Of	Nonketotic hypoglycemia	OMIM:201475
Neurologic, Endocrine, And Pancreatic Disease, Multisystem, Infantile-Onset 2	Hypertriglyceridemia, Hypoglycemia, Neonatal hypoglycemia	OMIM:619418
Metabolic Crises, Recurrent, With Rhabdomyolysis, Cardiac Arrhythmias, And Neurodegeneration	Hypothyroidism, Hypoglycemia, Premature thelarche, Premature pubarche	OMIM:616878
Pancreatic And Cerebellar Agenesis	Hyperglycemia, Diabetes mellitus, Hypoglycemia	OMIM:609069
Congenital Disorder Of Glycosylation With Defective Fucosylation 1	Hypothyroidism, Hypoglycemia	OMIM:618005
Non-Acquired Panhypopituitarism	Ectopic posterior pituitary, Ectopic anterior pituitary gland, Hypoglycemia, Decreased response t...	ORPHA:90695
Carnitine-Acylcarnitine Translocase Deficiency	Fasting hypoglycemia, Hypoketotic hypoglycemia	ORPHA:159
Carnitine Palmitoyl Transferase Ii Deficiency, Severe Infantile Form	Hypoketotic hypoglycemia	ORPHA:228305
Midface Hypoplasia, Obesity, Developmental Delay, And Neonatal Hypotonia	Neonatal hypoglycemia	OMIM:608624
3-Methylcrotonyl-Coa Carboxylase 2 Deficiency	Hypoglycemia	OMIM:210210
Multiple Acyl-Coa Dehydrogenase Deficiency	Hypoglycemia	ORPHA:26791
Macrocephaly-Intellectual Disability-Neurodevelopmental Disorder-Small Thorax Syndrome	Neonatal hypoglycemia	ORPHA:457485
Carnitine Palmitoyltransferase Ii Deficiency, Lethal Neonatal	Nonketotic hypoglycemia, Hypoglycemia	OMIM:608836
Congenital Disorder Of Glycosylation, Type It	Decreased serum insulin-like growth factor 1, Hypoglycemia, Delayed puberty	OMIM:614921
Steinert Myotonic Dystrophy	Diabetes mellitus, Hypergonadotropic hypogonadism, Decreased response to growth hormone stimulati...	ORPHA:273
Classic Congenital Adrenal Hyperplasia Due To 21-Hydroxylase Deficiency	Decreased circulating cortisol level, Hypogonadotropic hypogonadism, Precocious puberty in female...	ORPHA:90794
Intellectual Disability-Macrocephaly-Hypotonia-Behavioral Abnormalities Syndrome	Hypoglycemia	ORPHA:457279
Combined Oxidative Phosphorylation Deficiency 37	Hypoglycemia	OMIM:618329
Isolated Complex I Deficiency	Diabetes mellitus, Hypoglycemia	ORPHA:2609
3-Methylglutaconic Aciduria Type 7	Hypothyroidism, Neonatal hypoglycemia	ORPHA:445038
Growth Retardation, Impaired Intellectual Development, Hypotonia, And Hepatopathy	Hypoglycemia	OMIM:617093
Mitochondrial Trifunctional Protein Deficiency 1	Hypoketotic hypoglycemia	OMIM:609015
Combined Oxidative Phosphorylation Defect Type 39	Neonatal hypoglycemia	ORPHA:565624
Immunodeficiency 59 And Hypoglycemia	Hypoglycemia	OMIM:233600
Cataracts, Growth Hormone Deficiency, Sensory Neuropathy, Sensorineural Hearing Loss, And Skeletal Dysplasia	Central adrenal insufficiency, Hypoglycemia, Decreased response to growth hormone stimulation test	OMIM:616007
Bloom Syndrome	Insulin resistance, Diabetes mellitus	ORPHA:125
Neurodevelopmental Disorder With Hypotonia, Dysmorphic Facies, And Skeletal Anomalies, With Or Without Seizures	Hypoglycemia	OMIM:620224
Carnitine Palmitoyl Transferase Ii Deficiency, Neonatal Form	Hyperlipidemia, Hypoketotic hypoglycemia	ORPHA:228308
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)	Hypoglycemia	OMIM:251880
Cerebral Visual Impairment	Neonatal hypoglycemia	ORPHA:447788
Carbonic Anhydrase Va Deficiency, Hyperammonemia Due To	Hypoglycemia	OMIM:615751
Sotos Syndrome	Glucose intolerance, Neonatal hypoglycemia	OMIM:117550
Acyl-Coa Dehydrogenase 9 Deficiency	Nonketotic hypoglycemia	ORPHA:99901
Congenital Disorder Of Glycosylation, Type Iie	Hypoglycemia	OMIM:608779
Dilated Cardiomyopathy With Ataxia	Hypothyroidism, Neonatal hypoglycemia	ORPHA:66634
Bannayan-Riley-Ruvalcaba Syndrome	Neoplasm of the adrenal cortex, Hypoglycemia, Thyroid carcinoma, Hashimoto thyroiditis	ORPHA:109
Cholera	Hypoglycemia	ORPHA:173
Lipodystrophy, Congenital Generalized, Type 1	Diabetes mellitus, Hypertriglyceridemia, Decreased serum leptin, Hyperinsulinemia, Insulin-resist...	OMIM:608594
Neurodevelopmental Disorder With Hypotonia, Craniofacial Abnormalities, And Seizures	Hypoglycemia	OMIM:614501
X-Linked Dominant Chondrodysplasia Punctata	Neonatal hypoglycemia	ORPHA:35173
Mitochondrial Trifunctional Protein Deficiency	Hypoparathyroidism, Hypoketotic hypoglycemia	ORPHA:746
Fanconi-Bickel Syndrome	Postprandial hyperglycemia, Fasting hypoglycemia, Glycosuria	OMIM:227810
Alg12-Cdg	Decreased serum insulin-like growth factor 1, Recurrent hypoglycemia, Hypocholesterolemia	ORPHA:79324
Leigh Syndrome	Hypoglycemia	ORPHA:506
3-Methylglutaconic Aciduria, Type Viib	Neonatal hypoglycemia	OMIM:616271
Renal Agenesis, Bilateral	Nonketotic hypoglycemia	ORPHA:1848
Oculodentodigital Dysplasia	Hypoglycemia	ORPHA:2710
Lipodystrophy, Congenital Generalized, Type 2	Hypertriglyceridemia, Decreased serum leptin, Hyperinsulinemia, Insulin-resistant diabetes mellit...	OMIM:269700
Wars2-Related Combined Oxidative Phosphorylation Defect	Neonatal hypoglycemia	ORPHA:572798
Neurooculorenal Syndrome	Decreased circulating cortisol level, Ectopic posterior pituitary, Decreased circulating ACTH con...	OMIM:620305
Combined Pituitary Hormone Deficiencies, Genetic Forms	Ectopic posterior pituitary, Ectopic anterior pituitary gland, Hypoglycemia, Decreased response t...	ORPHA:95494
Mitochondrial Dna Depletion Syndrome 6 (Hepatocerebral Type)	Recurrent hypoglycemia, Hypoglycemia	OMIM:256810
Perlman Syndrome	Hypoglycemia, Pancreatic islet-cell hyperplasia	OMIM:267000
Glutaryl-Coa Dehydrogenase Deficiency	Fasting hypoglycemia	ORPHA:25
3-Hydroxy-3-Methylglutaric Aciduria	Nonketotic hypoglycemia, Recurrent hypoglycemia	ORPHA:20
Kabuki Syndrome 2	Neonatal hypoglycemia	OMIM:300867
Pyruvate Carboxylase Deficiency	Hyperglycemia, Hypoglycemia	ORPHA:3008
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)	Hypoglycemia	OMIM:617156
Shigellosis	Hypoglycemia	ORPHA:810
Holoprosencephaly	Diabetes mellitus, Hypoglycemia, Diabetes insipidus, Anterior hypopituitarism, Panhypopituitarism	ORPHA:2162
Intellectual Developmental Disorder, X-Linked, Syndromic, With Pigmentary Mosaicism And Coarse Facies	Precocious puberty, Hypoglycemia	OMIM:301066
Antley-Bixler Syndrome With Genital Anomalies And Disordered Steroidogenesis	Decreased circulating dehydroepiandrosterone concentration, Decreased circulating androstenedione...	OMIM:201750
Fatal Infantile Lactic Acidosis With Methylmalonic Aciduria	Hypoglycemia	ORPHA:17
Hereditary Fructose Intolerance	Reactive hypoglycemia	ORPHA:469
Mitochondrial Complex Iii Deficiency, Nuclear Type 1	Recurrent hypoglycemia, Hypoglycemia, Hyperglycemia	OMIM:124000
Methylmalonic Acidemia With Homocystinuria, Type Cblc	Hypoglycemia	ORPHA:79282
Deeah Syndrome	Anterior pituitary hypoplasia, Decreased response to growth hormone stimulation test, Decreased c...	OMIM:619004
Tyrosinemia, Type I	Hypoglycemia, Pancreatic islet-cell hyperplasia	OMIM:276700
Mitochondrial Complex I Deficiency, Nuclear Type 1	Hypoglycemia	OMIM:252010
Histiocytoid Cardiomyopathy	Hypoglycemia	ORPHA:137675
Hutchinson-Gilford Progeria Syndrome	Female hypogonadism, Decreased serum leptin, Insulin resistance, Delayed menarche, Pubertal devel...	ORPHA:740
Menkes Disease	Hypoglycemia	ORPHA:565
Atypical Werner Syndrome	Hypertriglyceridemia, Diabetes mellitus, Abnormal circulating leptin concentration, Insulin-resis...	ORPHA:79474
Fructose Intolerance, Hereditary	Hypoglycemia, Glycosuria	OMIM:229600
Primary Fanconi Renotubular Syndrome	Hypoglycemia, Glycosuria	ORPHA:3337
Prader-Willi Syndrome	Hypogonadotropic hypogonadism, Decreased response to growth hormone stimulation test, Precocious ...	OMIM:176270
Holoprosencephaly 1	Hypoglycemia, Diabetes insipidus, Adrenal hypoplasia	OMIM:236100
Atelis Syndrome 2	Elevated circulating thyroid-stimulating hormone concentration, Hyperinsulinemia	OMIM:620185
Simpson-Golabi-Behmel Syndrome	Hypoglycemia, Pancreatic islet-cell hyperplasia	ORPHA:373
Rajab Interstitial Lung Disease With Brain Calcifications 1	Hypoglycemia	OMIM:613658
Glycogen Storage Disease Of Heart, Lethal Congenital	Neonatal hypoglycemia	OMIM:261740
Beckwith-Wiedemann Syndrome	Adrenocortical cytomegaly, Hypoglycemia, Adrenocortical carcinoma, Pseudohypoparathyroidism, Hypo...	ORPHA:116
Acute Liver Failure	Hypoglycemia, Adrenal insufficiency	ORPHA:90062
3-Methylglutaconic Aciduria, Type Viii	Neonatal hypoglycemia	OMIM:617248
Costello Syndrome	Hypoglycemia	OMIM:218040
Mitochondrial Complex Iv Deficiency, Nuclear Type 5	Hyperglycemia, Hypoglycemia	OMIM:220111
Megalencephaly-Severe Kyphoscoliosis-Overgrowth Syndrome	Neonatal hypoglycemia	ORPHA:457359
Alström Syndrome	Hypertriglyceridemia, Precocious puberty in females, Decreased response to growth hormone stimula...	ORPHA:64
Marburg Hemorrhagic Fever	Hypoglycemia	ORPHA:99826
Beckwith-Wiedemann Syndrome	Adrenocortical carcinoma, Adrenocortical cytomegaly, Neonatal hypoglycemia	OMIM:130650
Pmm2-Cdg	Hypogonadotropic hypogonadism, Elevated circulating growth hormone concentration, Insulin resista...	ORPHA:79318
Turner Syndrome Due To Structural X Chromosome Anomalies	High urinary gonadotropin level, Increased circulating gonadotropin level, Hyperinsulinemia, Thyr...	ORPHA:99413
Turner Syndrome	High urinary gonadotropin level, Increased circulating gonadotropin level, Hyperinsulinemia, Thyr...	ORPHA:881
Mosaic Monosomy X	High urinary gonadotropin level, Increased circulating gonadotropin level, Hyperinsulinemia, Thyr...	ORPHA:99228
Monosomy X	High urinary gonadotropin level, Increased circulating gonadotropin level, Hyperinsulinemia, Thyr...	ORPHA:99226
Sotos Syndrome	Hypothyroidism, Neonatal hypoglycemia	ORPHA:821

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Fabp4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Fabp4.

No publications found that use IMPC mice or data for Fabp4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele	Allele Type	Produced
Fabp4^{tm1(KOMP)Vlcg}	Reporter-tagged deletion allele (with selection cassette)	ES Cells
Fabp4^{tm1a(KOMP)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Targeting vectors, ES Cells
Fabp4^{tm1e(KOMP)Wtsi}	Targeted, non-conditional allele	ES Cells
Fabp4^{em1(IMPC)Mhzh}	Deletion	Mice
Fabp4^{tm2a(KOMP)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Targeting vectors, ES Cells

Sequence

Guides

Sequence	Guide sequence	pam	chr	start	stop	strand	Genome build	gRNA Concentration	Truncated Guide	Reversed	Sanger service	Guide format	Guide source

Nucleases

Nuclease type	Nuclease class

Genotype primers

Sequence	Name

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