Gene: Mthfsl

Order

Name 5, 10-methenyltetrahydrofolate synthetase-like

Synonyms Gm2382

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:3780550    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Mthfsl

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mthfsl data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased grip strength Mthfsltm1b(EUCOMM)Hmgu HOM Male postnatal 6.03E-7
abnormal lens morphology Mthfsltm1b(EUCOMM)Hmgu HOM Female Male postnatal 7.08E-7
cataract Mthfsltm1b(EUCOMM)Hmgu HOM Male postnatal 1.53E-6
abnormal behavior Mthfsltm1b(EUCOMM)Hmgu HOM Male postnatal 4.94E-5
hypoactivity Mthfsltm1b(EUCOMM)Hmgu HOM Male postnatal 6.71E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Blood 2 No
Bone 2 No (1/539)
Bone marrow 2 No
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cecum 2 No (1/355)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Chest bone 2 No (2/2)
Colon 2 No (1/99)
Cranium 2 No
Diaphragm 2 No
Epididymis 2 No (4/106)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Harderian gland 2 No
Heart 2 No (3/562) (1/2)
Hindlimb 2 No
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (1/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Main olfactory bulb 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Parotid gland 2 No
Penis 2 No
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (1/2)
Prostate gland 2 No (5/562)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Stomach pyloric region 2 No
Striatum 2 No (4/562)
Sublingual gland 2 No
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Tongue 2 No
Trachea 2 No (3/562)
Trigeminal V nerve 2 No
Urinary bladder 2 No
Uterus 2 No (2/562)
Vagina 2 No
Vas deferens 2 No (1/360)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    digestive system
    cardiovascular system
    nervous system
    reproductive system
    musculoskeletal system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    5 Images
  • X-ray: XRay Images Lateral Orientation
    2 Images
  • Adult LacZ: LacZ Images Wholemount
    17 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Mthfsltm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Mthfsltm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene