Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Ripply1 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Cervical Vertebral Dysplasia | Cervical vertebral dysplasia, Cervical vertebral facet hypoplasia, Anterior atlanto-occipital dis... | OMIM:118005 | |
Spondylocostal Dysostosis 6, Autosomal Recessive | Cervical kyphosis, Hemivertebrae, Spinal canal stenosis, Scoliosis, Butterfly vertebrae | OMIM:616566 | |
Vertebral Hypoplasia With Lumbar Kyphosis | Vertebral hypoplasia, Lumbar kyphosis | OMIM:192900 | |
Osteomesopyknosis | Kyphosis, Sclerotic vertebral body, Scoliosis, Abnormal form of the vertebral bodies | ORPHA:2777 | |
Klippel-Feil Syndrome 3, Autosomal Dominant | Thoracic scoliosis, Cervical C3/C4 vertebral fusion, Cervical C5/C6 vertebrae fusion | OMIM:613702 | |
Acrodysplasia Scoliosis | Vertebral segmentation defect, Spina bifida occulta, Scoliosis | ORPHA:2956 | |
X-Linked Skeletal Dysplasia-Intellectual Disability Syndrome | Fused cervical vertebrae, Abnormal sacrum morphology, Thoracic hemivertebrae, Scoliosis | ORPHA:1436 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Ripply1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | ES Cells |
Ripply1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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