Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Syna by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Hereditary Persistence Of Fetal Hemoglobin-Beta-Thalassemia Syndrome | Pallor | ORPHA:46532 | |
Methylmalonic Acidemia With Homocystinuria, Type Cbld | Pallor | ORPHA:79283 | |
Peripheral Cone Dystrophy | Pallor | OMIM:609021 | |
Cone-Rod Dystrophy 11 | Pallor | OMIM:610381 | |
Osteoporosis-Oculocutaneous Hypopigmentation Syndrome | Short stature, Pallor | ORPHA:2786 | |
Optic Atrophy 1 | Pallor | OMIM:165500 | |
Dermatitis, Atopic | Dry skin, Pallor, Facial erythema | OMIM:603165 | |
Acute Peripheral Arterial Occlusion | Pallor | ORPHA:90064 | |
Benign Paroxysmal Torticollis Of Infancy | Pallor | ORPHA:71518 | |
Breath-Holding Spells | Pallor | OMIM:607578 | |
Leber Congenital Amaurosis 14 | Pallor | OMIM:613341 | |
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 2 | Growth delay, Pallor | OMIM:613561 | |
Acute Myelomonocytic Leukemia | Pallor | ORPHA:517 | |
Optic Atrophy 7 With Or Without Auditory Neuropathy | Pallor | OMIM:612989 | |
Hemoglobin D Disease | Pallor | ORPHA:90039 | |
Congenital Heart Block | Intrauterine growth retardation, Patent ductus arteriosus, Pallor | ORPHA:60041 | |
Primary Lateral Sclerosis, Juvenile | Pallor | OMIM:606353 | |
Familial Focal Epilepsy With Variable Foci | Pallor | ORPHA:98820 | |
X-Linked Sideroblastic Anemia | Pallor | ORPHA:75563 | |
Anemia, Congenital Dyserythropoietic, Type Ib | Growth delay, Short stature, Pallor | OMIM:615631 | |
Cyclic Vomiting Syndrome | Growth delay, Pallor | OMIM:500007 | |
Thiamine-Responsive Megaloblastic Anemia Syndrome | Short stature, Pallor | ORPHA:49827 | |
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome | Pallor | ORPHA:276608 | |
Spontaneous Periodic Hypothermia | Pallor | ORPHA:29822 | |
Retinitis Pigmentosa 51 | Pallor | OMIM:613464 | |
Hyperinsulinism Due To Ucp2 Deficiency | Pallor | ORPHA:276556 | |
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency | Pallor | ORPHA:276575 | |
Evans Syndrome | Pallor, Petechiae | ORPHA:1959 | |
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency | Pallor | ORPHA:276580 | |
Hyperinsulinism Due To Hnf1A Deficiency | Pallor | ORPHA:324575 | |
Renal Tubular Acidosis, Distal, 4, With Hemolytic Anemia | Short stature, Pallor | OMIM:611590 | |
Myopathic Ehlers-Danlos Syndrome | Pallor | ORPHA:536516 | |
Pyruvate Kinase Deficiency Of Red Cells | Intrauterine growth retardation, Pallor | OMIM:266200 | |
Fanconi Anemia, Complementation Group I | Intrauterine growth retardation, Short stature, Pallor | OMIM:609053 | |
Beta-Thalassemia | Pallor, Skin ulcer | ORPHA:848 | |
Anemia, Hypochromic Microcytic, With Iron Overload 2 | Growth delay, Pallor | OMIM:615234 | |
Leishmaniasis | Pallor, Skin ulcer | ORPHA:507 | |
Myelofibrosis | Pallor, Purpura | OMIM:254450 | |
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 1 | Growth delay, Pallor, Delayed puberty | OMIM:600462 | |
Irida Syndrome | Pallor | ORPHA:209981 | |
Dravet Syndrome | Pallor | ORPHA:33069 | |
Primary Myelofibrosis | Ecchymosis, Pallor, Petechiae, Purpura | ORPHA:824 | |
Non-Functioning Paraganglioma | Pallor | ORPHA:94080 | |
Hb Bart'S Hydrops Fetalis | Pallor | ORPHA:163596 | |
Kcnq2-Related Epileptic Encephalopathy | Pallor, Facial erythema | ORPHA:439218 | |
Megaloblastic Anemia Due To Dihydrofolate Reductase Deficiency | Pallor | OMIM:613839 | |
Drug-Induced Autoimmune Hemolytic Anemia | Pallor | ORPHA:90037 | |
Cold Agglutinin Disease | Pallor | ORPHA:56425 | |
Deafness-Lymphedema-Leukemia Syndrome | Pallor | ORPHA:3226 | |
Anemia, Sideroblastic, 1 | Anemic pallor | OMIM:300751 | |
Retinitis Pigmentosa 75 | Pallor | OMIM:617023 | |
Acquired Idiopathic Sideroblastic Anemia | Pallor | ORPHA:75564 | |
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency | Pallor | OMIM:246450 | |
Mixed-Type Autoimmune Hemolytic Anemia | Pallor | ORPHA:90036 | |
Congenital Dyserythropoietic Anemia Type Iii | Short stature, Pallor | ORPHA:98870 | |
6-Pyruvoyl-Tetrahydropterin Synthase Deficiency | Pallor | ORPHA:13 | |
Myopathy, Mitochondrial, And Ataxia | Growth delay, Short stature, Pallor | OMIM:617675 | |
Rheumatic Fever | Erythema, Pallor | ORPHA:3099 | |
Idiopathic Pulmonary Hemosiderosis | Pallor | ORPHA:99931 | |
Congenital Hyperinsulinism Due To Hnf4A Deficiency | Pallor | ORPHA:263455 | |
Cone-Rod Dystrophy 8 | Pallor | OMIM:605549 | |
Elliptocytosis 1 | Pallor | OMIM:611804 | |
Tay-Sachs Disease | Pallor | OMIM:272800 | |
American Trypanosomiasis | Pallor | ORPHA:3386 | |
Hereditary Spherocytosis | Growth delay, Pallor, Skin ulcer | ORPHA:822 | |
Autoimmune Hemolytic Anemia, Warm Type | Pallor | ORPHA:90033 | |
Severe Congenital Hypochromic Anemia With Ringed Sideroblasts | Growth delay, Pallor | ORPHA:300298 | |
Dominant Beta-Thalassemia | Growth delay, Pallor, Skin ulcer, Delayed puberty | ORPHA:231226 | |
Senior-Loken Syndrome 8 | Pallor | OMIM:616307 | |
Plummer-Vinson Syndrome | Pallor | ORPHA:54028 | |
Childhood Absence Epilepsy | Pallor | ORPHA:64280 | |
Beta-Thalassemia Intermedia | Pallor, Skin ulcer | ORPHA:231222 | |
Letterer-Siwe Disease | Pallor | OMIM:246400 | |
Sepsis In Premature Infants | Pallor, Petechiae, Purpura | ORPHA:90051 | |
Hereditary Folate Malabsorption | Pallor | ORPHA:90045 | |
Fructose-1,6-Bisphosphatase Deficiency | Pallor | ORPHA:348 | |
Sporadic Pheochromocytoma/Secreting Paraganglioma | Pallor | ORPHA:276621 | |
Beta-Thalassemia Major | Growth delay, Pallor, Skin ulcer, Delayed puberty | ORPHA:231214 | |
Beta-Ketothiolase Deficiency | Pallor | ORPHA:134 | |
Waldenström Macroglobulinemia | Pallor, Purpura | ORPHA:33226 | |
Severe Combined Immunodeficiency Due To Complete Rag1/2 Deficiency | Pallor | ORPHA:331206 | |
Non-Functioning Pituitary Adenoma | Pallor | ORPHA:91349 | |
Prolactinoma | Pallor, Delayed puberty | ORPHA:2965 | |
Imerslund-Gräsbeck Syndrome | Pallor | ORPHA:35858 | |
Generalized Juvenile Polyposis/Juvenile Polyposis Coli | Growth delay, Anemic pallor | ORPHA:329971 | |
Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema | Pallor | OMIM:194380 | |
Adenohypophysitis | Pallor | ORPHA:95512 | |
Aregenerative Anemia | Pallor | ORPHA:101096 | |
3-Hydroxy-3-Methylglutaric Aciduria | Pallor | ORPHA:20 | |
Incontinentia Pigmenti | Erythema, Short stature, Pallor | OMIM:308300 | |
Panhypophysitis | Pallor | ORPHA:95513 | |
Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency | Pallor | OMIM:300908 | |
Sheehan Syndrome | Dry skin, Pallor | ORPHA:91355 | |
Pituitary Apoplexy | Pallor | ORPHA:95613 | |
Diamond-Blackfan Anemia 1 | Intrauterine growth retardation, Spina bifida occulta, Short stature, Pallor | OMIM:105650 | |
Retinitis Pigmentosa And Erythrocytic Microcytosis | Pallor | OMIM:616959 | |
Hereditary Pheochromocytoma-Paraganglioma | Pallor | ORPHA:29072 | |
Systemic Mastocytosis With Associated Hematologic Neoplasm | Pallor | ORPHA:98849 | |
Fanconi Anemia, Complementation Group C | Intrauterine growth retardation, Anemic pallor, Short stature | OMIM:227645 | |
Refractory Anemia With Excess Blasts | Anemic pallor | ORPHA:86839 | |
Fumarase Deficiency | Pallor | OMIM:606812 | |
Alternating Hemiplegia Of Childhood | Pallor | ORPHA:2131 | |
Pearson Marrow-Pancreas Syndrome | Erythema, Pallor | OMIM:557000 | |
Esophageal Atresia | Growth delay, Pallor | ORPHA:1199 | |
Fanconi Anemia, Complementation Group E | Anemic pallor, Short stature | OMIM:600901 | |
Degcags Syndrome | Intrauterine growth retardation, Patent ductus arteriosus, Pallor | OMIM:619488 | |
Fanconi Anemia, Complementation Group A | Anemic pallor, Short stature | OMIM:227650 | |
Fanconi Anemia, Complementation Group D2 | Patent ductus arteriosus, Anemic pallor, Short stature | OMIM:227646 | |
Histiocytoid Cardiomyopathy | Pallor | ORPHA:137675 | |
Tsh-Secreting Pituitary Adenoma | Pallor, Delayed puberty | ORPHA:91347 | |
Idiopathic Hypereosinophilic Syndrome | Pallor | ORPHA:3260 | |
Diamond-Blackfan Anemia | Growth delay, Short stature, Pallor | ORPHA:124 | |
Autosomal Recessive Malignant Osteopetrosis | Growth delay, Pallor | ORPHA:667 | |
Infection-Related Hemolytic Uremic Syndrome | Pallor | ORPHA:544482 | |
Multiple Endocrine Neoplasia Type 2 | Pallor | ORPHA:653 | |
Von Hippel-Lindau Disease | Pallor | ORPHA:892 | |
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 3 | Pallor | OMIM:253280 | |
Goodpasture Syndrome | Pallor | OMIM:233450 | |
Congenital Total Pulmonary Venous Return Anomaly | Patent ductus arteriosus, Pallor | ORPHA:99125 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Synatm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | ES Cells |
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