Gene: Gba2

Order

Name glucosidase beta 2

Synonyms bile acid

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2654325    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Gba2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gba2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
male infertility Gba2tm1a(EUCOMM)Wtsi HOM Male postpartum stage 0.0
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Gba2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 4.62E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No (1/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/562) (1/2)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (1/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (2/2)
Uterus 2 No (2/562) (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse respiratory system digestive system cardiovascular system nervous system set of connective tissues reproductive system immune system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (24)
  • Gba2tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    lymph node, HET, Female, WTSI

show all 24 images

trunk (16)
  • Gba2tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    uterus, oviduct, ovary, HET, Female, WTSI

show all 16 images

digestive system (4)
  • Gba2tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    gall bladder, HET, Male, WTSI
nervous system (4)
  • Gba2tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    brain, HET, Male, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    pituitary gland, peripheral nervous system, HET, Male, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
immune system (3)
  • Gba2tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    lymph node, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    spleen, HET, Female, WTSI
cardiovascular system (2)
  • Gba2tm1a(EUCOMM)Wtsi
    heart, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    blood vessel, HET, Female, WTSI
endocrine system (2)
  • Gba2tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    parathyroid gland, HET, Female, WTSI
reproductive system (2)
  • Gba2tm1a(EUCOMM)Wtsi
    uterus, oviduct, ovary, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
respiratory system (2)
  • Gba2tm1a(EUCOMM)Wtsi
    trachea, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
urinary system (2)
  • Gba2tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    kidney, HET, Male, WTSI
integumental system (1)
  • Gba2tm1a(EUCOMM)Wtsi
    skin, HET, Female, WTSI
set of connective tissues (1)
  • Gba2tm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (93)
  • Gba2tm1a(EUCOMM)Wtsi
    head, HOM, Male, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    body, HOM, Male, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    forearm, HOM, Male, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    body, HOM, Male, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    head, HOM, Male, WTSI

show all 93 images

Eye Morphology (4)
  • Gba2tm1a(EUCOMM)Wtsi
    mydriasis, HOM, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    Fused cornea and lens, HOM, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    Fused cornea and lens, HOM, Female, WTSI
  • Gba2tm1a(EUCOMM)Wtsi
    corneal opacity, HOM, Female, WTSI
Skin Histopathology (1)
  • Gba2tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gba2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene