Gene: Adam32

Name a disintegrin and metallopeptidase domain 32

Status ES CellsMice
phenotype data available

Links MGI:2653822   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Adam32

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Adam32 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased lean body mass Adam32tm1b(KOMP)Wtsi HOM Male postnatal 1.81E-11
decreased bone mineral content Adam32tm1b(KOMP)Wtsi HOM Male postnatal 2.74E-8
impaired pupillary reflex Adam32tm1b(KOMP)Wtsi HOM Male postnatal 1.26E-7
decreased bone mineral density Adam32tm1b(KOMP)Wtsi HOM Male postnatal 4.45E-5
increased total body fat amount Adam32tm1b(KOMP)Wtsi HOM Male postnatal 7.2E-5

Download data as: TSV XLS


IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440)
Dorsal root ganglion 2 (1/3)
Ear 2 (1/440)
Embryo 2 (1/440)
Eye 2 (1/440)
Foot 2
Forebrain 2 (1/440)
Forelimb 2 (1/440)
Fronto-nasal process 2 (1/4)
Hand 2
Head 2 (5/440)
Heart 2 (1/440)
Hindbrain 2 (5/440)
Hindlimb 2 (1/440)
Liver 2 (1/440)
Lung 2 (1/440)
Mandibular process 2 (1/440)
Maxillary process 2 (1/440)
Midbrain 2 (1/440)
Nose 2 (1/5)
Oral cavity 2 (1/440)
Skin 2 (1/440)
Spinal cord 2 (1/4)
Tail 2 (1/440)
Tail somite 2 (1/440)

Associated Images

Phenotype associated images not available

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Adam32tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Adam32tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)