Gene: Slc24a4

Order

Name solute carrier family 24 (sodium/potassium/calcium exchanger), member 4

Synonyms
  • A930002M03Rik
  • NCKX4

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2447362    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Slc24a4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slc24a4 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Tooth - process of degenerative change Slc24a4tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
enlarged thymus Slc24a4tm1b(KOMP)Wtsi HET Female postnatal 0.0
preweaning lethality, incomplete penetrance Slc24a4tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased circulating alkaline phosphatase level Slc24a4tm1b(KOMP)Wtsi HOM Female postnatal 6.72E-8
increased circulating cholesterol level Slc24a4tm1b(KOMP)Wtsi HET Female Male postnatal 3.69E-6
increased circulating HDL cholesterol level Slc24a4tm1b(KOMP)Wtsi HET Female Male postnatal 5.91E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Gall bladder 2 No
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (1/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    digestive system
    cardiovascular system
    nervous system
    sensory organ
    reproductive system
    immune system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485)
Ear 2 (1/485)
Embryo 2 (1/485) (2/4)
Eye 2 (1/485)
Foot 2 (1/485)
Forebrain 2 (1/485)
Forelimb 2 (1/485)
Hand 2 (1/485)
Head 2 (5/485) (2/4)
Heart 2 (1/485)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Midbrain 2 (1/485)
Oral cavity 2 (1/485)
Skin 2 (1/485)
Tail 2 (1/485)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    19 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    18 Images
  • X-ray: XRay Images Dorso Ventral
    19 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    9 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Slc24a4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slc24a4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene