Gene: Galnt18

Order

Name polypeptide N-acetylgalactosaminyltransferase 18

Synonyms
  • 2900011G21Rik
  • Galntl4

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2446239    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Galnt18

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Galnt18 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased NK cell number Galnt18tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased circulating insulin level Galnt18tm1b(KOMP)Wtsi HOM Female Male postnatal 2.99E-8
decreased food intake Galnt18tm1b(KOMP)Wtsi HOM Male postnatal 3.78E-8
increased red blood cell distribution width Galnt18tm1b(KOMP)Wtsi HOM Male postnatal 1.96E-7
decreased total body fat amount Galnt18tm1b(KOMP)Wtsi HOM Female Male postnatal 2.23E-7
increased lean body mass Galnt18tm1b(KOMP)Wtsi HOM Female Male postnatal 9.89E-7
decreased circulating fructosamine level Galnt18tm1b(KOMP)Wtsi HOM Male postnatal 1.03E-6
increased circulating fructosamine level Galnt18tm1b(KOMP)Wtsi HOM Female postnatal 1.03E-6
decreased circulating glucose level Galnt18tm1b(KOMP)Wtsi HOM Female Male postnatal 1.68E-6
decreased circulating serum albumin level Galnt18tm1b(KOMP)Wtsi HOM Male postnatal 3.46E-5
increased circulating serum albumin level Galnt18tm1b(KOMP)Wtsi HOM Female postnatal 3.46E-5
improved glucose tolerance Galnt18tm1b(KOMP)Wtsi HOM Female Male postnatal 9.19E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No
Bone 2 No (1/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Eye 2 No (2/2)
Gall bladder 2 No
Heart 2 No (1/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (1/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No (1/2)
Mammary gland 2 No (1/2)
Esophagus 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle tissue 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (21)
  • Galnt18tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    adrenal gland, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    hypothalamus, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    spinal cord, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    pituitary gland, HET, Female, WTSI

show all 21 images

trunk (15)
  • Galnt18tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    adrenal gland, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    spinal cord, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    gall bladder, HET, Female, WTSI

show all 15 images

digestive system (4)
  • Galnt18tm1b(KOMP)Wtsi
    gall bladder, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    oesophagus, HET, Female, WTSI
nervous system (3)
  • Galnt18tm1b(KOMP)Wtsi
    hypothalamus, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    spinal cord, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    pituitary gland, HET, Female, WTSI
reproductive system (3)
  • Galnt18tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    ovary, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    prostate gland, HET, Male, WTSI
exocrine system (2)
  • Galnt18tm1b(KOMP)Wtsi
    mammary gland, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    prostate gland, HET, Male, WTSI
immune system (2)
  • Galnt18tm1b(KOMP)Wtsi
    lymph node, mesenteric lymph node, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    thymus, HET, Female, WTSI
integumental system (2)
  • Galnt18tm1b(KOMP)Wtsi
    mammary gland, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    skin, HET, Female, WTSI
respiratory system (2)
  • Galnt18tm1b(KOMP)Wtsi
    lung, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    trachea, HET, Male, WTSI
cardiovascular system (1)
  • Galnt18tm1b(KOMP)Wtsi
    heart, HET, Female, WTSI
endocrine system (1)
  • Galnt18tm1b(KOMP)Wtsi
    adrenal gland, HET, Male, WTSI
musculoskeletal system (1)
  • Galnt18tm1b(KOMP)Wtsi
    bone, rib, HET, Female, WTSI
sensory organ (1)
  • Galnt18tm1b(KOMP)Wtsi
    eye, HET, Male, WTSI
urinary system (1)
  • Galnt18tm1b(KOMP)Wtsi
    kidney, HET, Male, WTSI

Associated Images

Associated Images
  • Mesenteric Lymph Node Immunophenotyping: Images associated with FACS analysis
    5 Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (100)
  • Galnt18tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    HOM, Female, WTSI

show all 100 images

Dysmorphology (6)
  • Galnt18tm1b(KOMP)Wtsi
    head, abnormal snout morphology, asymmetric snout, malocclusion, HOM, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    head, abnormal snout morphology, asymmetric snout, HOM, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    abnormal coat/hair pigmentation, HOM, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    head, abnormal snout morphology, asymmetric snout, HOM, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    head, abnormal snout morphology, HOM, Male, WTSI

show all 6 images

Histology Slide (4)
  • Galnt18tm1b(KOMP)Wtsi
    TS20 skin, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    TS20 tail, HET, Male, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    TS20 oral cavity, HET, Female, WTSI
  • Galnt18tm1b(KOMP)Wtsi
    TS20 heart, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Galnt18tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Galnt18tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene