Gene Summary

Name:
keratin 26
Synonyms:
4732407F15Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal seminal vesicle morphology Krt26em1(IMPC)Kmpc HOM Early adult 0.00
abnormal skin coloration Krt26em1(IMPC)Kmpc HOM Late adult 4.36×10-05
abnormal digit morphology Krt26em1(IMPC)Kmpc HOM Late adult 2.46×10-05
decreased heart weight Krt26em1(IMPC)Kmpc HOM Late adult 2.71×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

X-ray

XRay Images Whole Body Dorso Ventral

10 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

X-ray

XRay Images Whole Body Dorso Ventral

10 Images

X-ray

XRay Images Hind Leg and Hip

10 Images

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

X-ray

XRay Images Forepaw

10 Images

X-ray

XRay Images Hind Leg and Hip

10 Images

X-ray

XRay Images Skull Lateral Orientation

10 Images

X-ray

XRay Images Skull Lateral Orientation

10 Images

X-ray

XRay Images Forepaw

10 Images

Eye Morphology

Images Slit Lamp

1 Images

Human diseases caused by Krt26 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Krt26 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Hyperpigmentation With Or Without Hypopigmentation, Familial Progressive
Progressive hyperpigmentation, Hypermelanotic macule, Hypopigmented skin patches, Multiple lentig... OMIM:145250

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Krt26

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Krt26.

No publications found that use IMPC mice or data for Krt26.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Krt26tm38477(L1L2_gt0) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Krt26tm38477(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Krt26tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells
Krt26tm354748(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Krt26em1(IMPC)Kmpc Deletion Mice

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