Gene: Zzef1

Order

Name zinc finger, ZZ-type with EF hand domain 1

Synonyms
  • C130099L13Rik
  • 8430405D05Rik

Status ES CellsMice
tm2
Mice
tm2.1
phenotype data available

Links MGI:2444286    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Zzef1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Zzef1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased mean corpuscular hemoglobin Zzef1tm2.1(KOMP)Vlcg HOM Female Male postnatal 8.54E-11
decreased total body fat amount Zzef1tm2.1(KOMP)Vlcg HOM Female Male postnatal 8.69E-9
abnormal sleep behavior Zzef1tm2.1(KOMP)Vlcg HOM Female Male postnatal 1.12E-7
decreased circulating free fatty acid level Zzef1tm2.1(KOMP)Vlcg HOM Male postnatal 1.45E-5
decreased grip strength Zzef1tm2.1(KOMP)Vlcg HOM Female Male postnatal 1.67E-5
decreased erythrocyte cell number Zzef1tm2.1(KOMP)Vlcg HOM Female Male postnatal 3.65E-5
absent teeth Zzef1tm2.1(KOMP)Vlcg HOM Male postnatal 3.93E-5
abnormal coat/hair pigmentation Zzef1tm2.1(KOMP)Vlcg HOM Female postnatal 6.36E-5
increased lean body mass Zzef1tm2.1(KOMP)Vlcg HOM Male postnatal 8.52E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415) (4/4)
Aorta 4 No (4/4)
Blood 4 No
Bone marrow 4 No (2/4)
Brain 4 No (2/4)
Brainstem 4 No
Brown adipose tissue 4 No (4/4)
Cartilage tissue 4 No
Cecum 4 No (12/383) (3/4)
Cerebellum 4 No (4/4)
Cerebral cortex 4 No
Chest bone 4 No (2/4)
Colon 4 No (12/127) (4/4)
Diaphragm 4 No (2/4)
Duodenum 4 No (2/127) (4/4)
Epididymis 4 No (18/134) (2/4)
Esophagus 4 No (7/415) (3/4)
Eye 4 No (4/4)
Gall bladder 4 No (1/4)
Gonadal fat pad 4 No (3/4)
Harderian gland 4 No (4/4)
Heart 4 No
Hindlimb 4 No
Hippocampus 4 No
Hypothalamus 4 No
Ileum 4 No (14/127) (4/4)
Jejunum 4 No (6/127) (4/4)
Kidney 4 No (18/584) (4/4)
Large intestine 4 No (10/584)
Liver 4 No (4/4)
Lower urinary tract 4 No
Lung 4 No (4/4)
Lymph node 4 No
Mammary gland 4 No
Mesenteric lymph node 4 No (3/4)
Mesenteric adipose tissue 4 No (4/4)
Midbrain 4 No (4/4)
Olfactory lobe 4 No (4/4)
Ovary 4 No (1/584) (2/4)
Oviduct 4 No (2/4)
Pancreas 4 No (5/584) (4/4)
Parathyroid gland 4 No (2/4)
Parotid gland 4 No (1/4)
Penis 4 No (1/4)
Peripheral nervous system 4 No
Peyer's patch 4 No
Pituitary gland 4 No (4/4)
Prostate gland 4 No (12/584) (1/4)
Quadriceps 4 No (3/4)
Sciatic nerve 4 No (3/4)
Skeletal muscle 4 No
Skin 4 No (4/4)
Small intestine 4 No (9/584)
Spinal cord 4 No (3/4)
Spleen 4 No (2/584) (4/4)
Stomach 4 No (12/584) (4/4)
Stomach pyloric region 4 No
Striatum 4 No
Sublingual gland 4 No (2/4)
Submandibular gland 4 No (2/132) (2/4)
Testis 4 No (2/584) (2/4)
Thymus 4 No (3/4)
Thyroid gland 4 No (15/584) (3/4)
Tongue 4 No (5/127) (4/4)
Trachea 4 No (3/4)
Trigeminal V nerve 4 No (2/4)
Urinary bladder 4 No (4/4)
Uterus 4 No (2/4)
Vagina 4 No (1/4)
Vas deferens 4 No (15/388) (2/4)
Vascular system 4 No
Vesicular gland 4 No (2/4)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system limb digestive system cardiovascular system set of connective tissues reproductive system adipose tissue musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/3)
Dorsal root ganglion 2 (1/47) (1/3)
Ear 2 (1/485) (1/3)
Embryo 2 (1/485) (2/3)
Eye 2 (1/485) (2/3)
Foot 2 (1/485) (2/3)
Forebrain 2 (1/485) (2/3)
Forelimb 2 (1/485) (2/3)
Fronto-nasal process 2 (1/48) Image Only
Hand 2 (1/485) (2/3)
Head 2 (5/485) (2/3)
Heart 2 (1/485) (2/3)
Hindbrain 2 (6/485) (2/3)
Hindlimb 2 (1/485) (2/3)
Liver 2 (1/485)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/3)
Maxillary process 2 (1/485) (1/3)
Midbrain 2 (1/485) (2/3)
Nose 2 (1/51) (2/3)
Oral cavity 2 (1/485) Image Only
Skin 2 (1/485) (1/3)
Spinal cord 2 (1/50) (2/3)
Tail 2 (1/485) (1/3)
Tail somite 2 (1/485) (1/3)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    35 Images
  • X-ray: XRay Images Dorso Ventral
    57 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • Sleep Wake: Wake state (bmp file)
    7 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    13 Images
  • Combined SHIRPA and Dysmorphology
    5 Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
  • Electroretinography 2: Rod and cone PDF
    1 Images
  • X-ray: XRay Images Forepaw
    13 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Zzef1tm2(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Zzef1tm2.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue
Zzef1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Zzef1tm251649(L1L2_Bact_P)
Vector
Gene