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Gene: Gpr179 MGI:2443409

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
G protein-coupled receptor 179
Synonyms:
5330439C02Rik

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Gpr179 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Gpr179 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Night Blindness, Congenital Stationary, Type 1E
OMIM:614565
Congenital Stationary Night Blindness
ORPHA:215

The table below shows human diseases predicted to be associated to Gpr179 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Cortical Blindness-Intellectual Disability-Polydactyly Syndrome
Abnormality of visual evoked potentials ORPHA:1389
Night Blindness, Congenital Stationary, Type 1E
OMIM:614565
Congenital Stationary Night Blindness
ORPHA:215

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Gpr179

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Gpr179.

There are 2 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Mice Lacking Gpr179 with Complete Congenital Stationary Night Blindness Are a Good Model for Myopia. International journal of molecular sciences (December 2022) Gpr179tm1a(KOMP)Mbp PMC9820543
A New Mouse Model for Complete Congenital Stationary Night Blindness Due to Gpr179 Deficiency. International journal of molecular sciences (April 2021) Gpr179tm1a(KOMP)Mbp PMC8122890

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Gpr179tm1e(KOMP)Mbp Targeted, non-conditional allele ES Cells
Gpr179tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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