Gene: Rnf157

Name ring finger protein 157

Synonyms
  • A130073L17Rik
  • 2610036E23Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2442484   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Rnf157

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rnf157 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased anti-nuclear antigen antibody level Rnf157tm1b(EUCOMM)Wtsi HOM Female Male postnatal 0.0
abnormal lens morphology Rnf157tm1b(EUCOMM)Wtsi HOM Male postnatal 1.55E-5
cataract Rnf157tm1b(EUCOMM)Wtsi HOM Male postnatal 1.55E-5
decreased circulating phosphate level Rnf157tm1b(EUCOMM)Wtsi HOM Female postnatal 1.81E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No (1/562) (2/2)
Blood vessel 2 No
Bone 2 No (1/539) (2/2)
Brain 2 No (5/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (19/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/562)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562) (2/2)
Testis 2 No (3/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse cardiovascular system nervous system reproductive system musculoskeletal system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (6)
  • Rnf157tm1b(EUCOMM)Wtsi
    ADRENAL GLAND, HET, Female, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    AORTA, HET, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    OVIDUCT, HET, Female, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    BONE, RIB, HET, Male, WTSI

show all 6 images

nervous system (3)
  • Rnf157tm1b(EUCOMM)Wtsi
    OLFACTORY LOBE, HET, Female, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    TRIGEMINAL V NERVE, PERIPHERAL NERVOUS SYSTEM, HET, Female, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    SPINAL CORD, HET, Female, WTSI
reproductive system (2)
  • Rnf157tm1b(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    OVIDUCT, HET, Female, WTSI
cardiovascular system (1)
  • Rnf157tm1b(EUCOMM)Wtsi
    AORTA, HET, Male, WTSI
endocrine system (1)
  • Rnf157tm1b(EUCOMM)Wtsi
    ADRENAL GLAND, HET, Female, WTSI
musculoskeletal system (1)
  • Rnf157tm1b(EUCOMM)Wtsi
    BONE, RIB, HET, Male, WTSI

Associated Images

Associated Images
  • Anti-nuclear antibody assay
    6 Images
  • X-ray: XRay Images Dorso Ventral
    45 Images
  • X-ray: XRay Images Lateral Orientation
    30 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • Eye Morphology: Images Ophthalmoscopy
    2 Images
  • Eye Morphology: Images Slit Lamp
    7 Images
  • X-ray: XRay Images Skull Lateral Orientation
    15 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
Legacy Phenotype Associated Images
Xray (75)
  • Rnf157tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 75 images

Brain Histopathology (9)
  • Rnf157tm1b(EUCOMM)Wtsi
    3RD VENTRICLE, enlarged third ventricle, HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    decreased corpus callosum size, HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    CORPUS CALLOSUM, decreased corpus callosum size, HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 9 images

Eye Morphology (9)
  • Rnf157tm1b(EUCOMM)Wtsi
    cataracts, HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    cataracts, HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    cataracts, HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    abnormal cornea morphology, HOM, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    cataracts, HOM, Male, WTSI

show all 9 images

Histology Slide (4)
  • Rnf157tm1b(EUCOMM)Wtsi
    HET, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HET, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HET, Male, WTSI
  • Rnf157tm1b(EUCOMM)Wtsi
    HET, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rnf157tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rnf157tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Rnf157tm154(L1L2_gt1)
Vector
Gene