Gene: Kctd15

Order

Name potassium channel tetramerisation domain containing 15

Synonyms MGC25497

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2385276    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Kctd15

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Kctd15 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Kctd15tm1b(EUCOMM)Wtsi HOM embryonic day 15.5 0.0
prenatal lethality prior to heart atrial septation Kctd15tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 14.5 0.0
preweaning lethality, complete penetrance Kctd15tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
increased lymphocyte cell number Kctd15tm1b(EUCOMM)Wtsi HET Female postnatal 7.12E-6
decreased food intake Kctd15tm1b(EUCOMM)Wtsi HET Female Male postnatal 1.97E-5
abnormal behavior Kctd15tm1b(EUCOMM)Wtsi HET Female Male postnatal 3.85E-5
decreased circulating alkaline phosphatase level Kctd15tm1b(EUCOMM)Wtsi HET Female postnatal 8.06E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (1/2)
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (1/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (2/2)
Lung 2 No (1/2)
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Peripheral nervous system 2 No (1/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No (1/2)
Skin 2 No (1/2)
Small intestine 2 No (9/584) (1/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No (1/2)
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    16 Images
  • X-ray: XRay Images Lateral Orientation
    42 Images
  • X-ray: XRay Images Dorso Ventral
    26 Images
  • X-ray: XRay Images Hind Leg and Hip
    16 Images
  • Gross Pathology and Tissue Collection
    8 Images
  • Eye Morphology: Images Ophthalmoscopy
    20 Images
  • Adult LacZ: LacZ Images Section
    45 Images
  • Eye Morphology: Images Slit Lamp
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Kctd15tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Kctd15tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Kctd15tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Kctd15tm47323(L1L2_gt0)
Vector
Gene