Gene: Ube2e2

Order

Name ubiquitin-conjugating enzyme E2E 2

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2384997    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Ube2e2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ube2e2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
short tibia Ube2e2tm1b(KOMP)Wtsi HOM Female Male postnatal 1.08E-5
increased kidney weight Ube2e2tm1b(KOMP)Wtsi HOM Female Male postnatal 8.63E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415) (1/4)
Aorta 4 No (2/4)
Blood 4 No
Bone marrow 4 No
Brain 4 No (2/4)
Brainstem 4 No
Brown adipose tissue 4 No
Cartilage tissue 4 No
Cecum 4 No (12/383) (4/4)
Cerebellum 4 No (4/4)
Cerebral cortex 4 No
Chest bone 4 No (2/4)
Colon 4 No (12/127) (4/4)
Diaphragm 4 No
Duodenum 4 No (2/127)
Epididymis 4 No (18/134) (2/4)
Esophagus 4 No (7/415)
Eye 4 No (2/4)
Gall bladder 4 No (2/4)
Gonadal fat pad 4 No
Harderian gland 4 No (4/4)
Heart 4 No
Hindlimb 4 No
Hippocampus 4 No
Hypothalamus 4 No
Ileum 4 No (14/127) (3/4)
Jejunum 4 No (6/127) (2/4)
Kidney 4 No (18/584) (3/4)
Large intestine 4 No (10/584)
Liver 4 No
Lower urinary tract 4 No
Lung 4 No
Lymph node 4 No
Mammary gland 4 No (1/4)
Mesenteric lymph node 4 No (2/4)
Mesenteric adipose tissue 4 No
Midbrain 4 No (4/4)
Olfactory lobe 4 No (3/4)
Ovary 4 No (1/584)
Oviduct 4 No (1/4)
Pancreas 4 No (5/584)
Parathyroid gland 4 No (3/4)
Parotid gland 4 No
Penis 4 No (1/4)
Peripheral nervous system 4 No
Peyer's patch 4 No
Pituitary gland 4 No (4/4)
Prostate gland 4 No (12/584) (2/4)
Quadriceps 4 No
Sciatic nerve 4 No
Skeletal muscle 4 No
Skin 4 No (2/4)
Small intestine 4 No (9/584)
Spinal cord 4 No (3/4)
Spleen 4 No (2/584)
Stomach 4 No (12/584) (4/4)
Stomach pyloric region 4 No
Striatum 4 No
Sublingual gland 4 No
Submandibular gland 4 No (2/132)
Testis 4 No (2/584) (2/4)
Thymus 4 No
Thyroid gland 4 No (15/584)
Tongue 4 No (5/127) (1/4)
Trachea 4 No
Trigeminal V nerve 4 No (2/4)
Urinary bladder 4 No (4/4)
Uterus 4 No (2/4)
Vagina 4 No (1/4)
Vas deferens 4 No (15/388) (2/4)
Vascular system 4 No
Vesicular gland 4 No (2/4)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3 (6/485) (4/5)
Ear 3 (1/485) (1/5)
Embryo 3 (1/485) (5/5)
Eye 3 (1/485) (3/5)
Foot 3 (1/485)
Forebrain 3 (1/485) (4/5)
Forelimb 3 (1/485) (2/5)
Hand 3 (1/485) (1/5)
Head 3 (5/485) (5/5)
Heart 3 (1/485) (2/5)
Hindbrain 3 (6/485) (4/5)
Hindlimb 3 (1/485) (1/5)
Liver 3 (1/485) (1/5)
Lung 3 (1/485) (2/5)
Mandibular process 3 (1/485) (2/5)
Maxillary process 3 (1/485) (2/5)
Midbrain 3 (1/485) (4/5)
Oral cavity 3 (1/485) (2/5)
Skin 3 (1/485) (2/5)
Tail 3 (1/485) (5/5)
Tail somite 3 (1/485) (1/5)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    32 Images
  • Echo: M-Mode Images
    32 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images
  • X-ray: XRay Images Dorso Ventral
    51 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ube2e2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ube2e2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue