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Gene: Gin1 MGI:2182036

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Gene Summary

Name:
gypsy retrotransposon integrase 1
Synonyms:
4930429M06Rik,  Zh2c2,  4930429M06

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal heart shape Gin1em1(IMPC)Mbp HOM Early adult 0.00
abnormal thymus morphology Gin1em1(IMPC)Mbp HOM Early adult 0.00
abnormal heart morphology Gin1em1(IMPC)Mbp HOM Early adult 0.00
enlarged thymus Gin1em1(IMPC)Mbp HOM Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Dorso Ventral

30 Images

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X-ray

XRay Images Whole Body Lateral Orientation

10 Images

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Human diseases caused by Gin1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Gin1 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Isolated Anencephaly
Thymus hyperplasia ORPHA:563609
Proteus-Like Syndrome
Splenomegaly, Abnormality of the parathyroid gland, Thymus hyperplasia, Polycystic ovaries ORPHA:2969
Myopathy, Epilepsy, And Progressive Cerebral Atrophy
Thymus hyperplasia OMIM:619036
Proteus Syndrome
Thymus hyperplasia, Testicular neoplasm, Enlarged polycystic ovaries, Splenomegaly, Ovarian neopl... ORPHA:744

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Gin1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Gin1.

No publications found that use IMPC mice or data for Gin1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Gin1em1(IMPC)Mbp Exon Deletion Mice, Tissue
Gin1tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Gin1tm109047(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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