Gene: Cldn16

Name claudin 16

Synonyms
  • claudin-16
  • PCLN1
  • paracellin-1

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2148742   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Cldn16

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cldn16 data for that phenotype.

No results meet the p-value threshold


Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (5/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (1/2)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (19/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562) (1/2)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (3/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (1/2)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system set of connective tissues reproductive system immune system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (6)
  • Cldn16tm1a(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    SPLEEN, HET, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    THYMUS, HET, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    KIDNEY, HET, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    OVARY, HET, Female, WTSI

show all 6 images

immune system (4)
  • Cldn16tm1a(KOMP)Wtsi
    SPLEEN, HET, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    THYMUS, HET, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    LYMPH NODE, HET, Male, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    THYMUS, HET, Male, WTSI
reproductive system (2)
  • Cldn16tm1a(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    OVARY, HET, Female, WTSI
endocrine system (1)
  • Cldn16tm1a(KOMP)Wtsi
    THYROID GLAND, HET, Female, WTSI
urinary system (1)
  • Cldn16tm1a(KOMP)Wtsi
    KIDNEY, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (66)
  • Cldn16tm1a(KOMP)Wtsi
    TRUNK, HOM, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    TRUNK, HOM, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    HEAD, HOM, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    HEAD, HOM, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    TRUNK, HOM, Male, WTSI

show all 66 images

Skin Histopathology (2)
  • Cldn16tm1a(KOMP)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI
  • Cldn16tm1a(KOMP)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cldn16tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cldn16tm1e(KOMP)Mbp Targeted, non-conditional allele
Vector
Gene
Cldn16tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Cldn16tm46517(L1L2_hubi_P)
Vector
Gene