Gene: Brpf3

Order

Name bromodomain and PHD finger containing, 3

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2146836    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Brpf3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Brpf3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Brpf3tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased circulating potassium level Brpf3tm1a(EUCOMM)Wtsi HET Female Male postnatal 2.45E-7
decreased circulating glucose level Brpf3tm1a(EUCOMM)Wtsi HET Female Male postnatal 6.06E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 6 No (6/6)
Aorta 6 No
Blood vessel 6 No
Bone 6 No (2/6)
Brain 6 No (6/6)
Brainstem 6 No
Brown adipose tissue 6 No
Cartilage tissue 6 No (6/6)
Cerebellum 6 No
Cerebral cortex 6 No
Eye 6 No (2/6)
Gall bladder 6 No
Heart 6 No (4/6)
Hippocampus 6 No
Hypothalamus 6 No
Kidney 6 No (18/584) (6/6)
Large intestine 6 No (10/584) (1/6)
Liver 6 No
Lower urinary tract 6 No (4/6)
Lung 6 No (3/6)
Lymph node 6 No (1/6)
Mammary gland 6 No
Esophagus 6 No
Olfactory lobe 6 No
Ovary 6 No (1/584) (3/6)
Oviduct 6 No (3/6)
Pancreas 6 No (5/584) (1/6)
Parathyroid gland 6 No (2/6)
Peripheral nervous system 6 No (6/6)
Peyer's patch 6 No
Pituitary gland 6 No (6/6)
Prostate gland 6 No (12/584)
Skeletal muscle tissue 6 No
Skin 6 No
Small intestine 6 No (9/584) (2/6)
Spinal cord 6 No (6/6)
Spleen 6 No (2/584)
Stomach 6 No (12/584)
Striatum 6 No
Testis 6 No (2/584) (3/6)
Thymus 6 No (3/6)
Thyroid gland 6 No (15/584) (4/6)
Trachea 6 No (6/6)
Uterus 6 No (3/6)
White adipose tissue 6 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (22)
  • Brpf3tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    parathyroid gland, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    peripheral nervous system, pituitary gland, HET, Female, WTSI

show all 22 images

trunk (13)
  • Brpf3tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    stomach, HET, Female, WTSI

show all 13 images

nervous system (4)
  • Brpf3tm1a(EUCOMM)Wtsi
    peripheral nervous system, pituitary gland, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
digestive system (3)
  • Brpf3tm1a(EUCOMM)Wtsi
    stomach, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
endocrine system (2)
  • Brpf3tm1a(EUCOMM)Wtsi
    parathyroid gland, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
immune system (2)
  • Brpf3tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    lymph node, HET, Male, WTSI
reproductive system (2)
  • Brpf3tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
set of connective tissues (2)
  • Brpf3tm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    inguinal fat pad, HET, Female, WTSI
urinary system (2)
  • Brpf3tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
adipose tissue (1)
  • Brpf3tm1a(EUCOMM)Wtsi
    inguinal fat pad, HET, Female, WTSI
cardiovascular system (1)
  • Brpf3tm1a(EUCOMM)Wtsi
    heart, HET, Female, WTSI
exocrine system (1)
  • Brpf3tm1a(EUCOMM)Wtsi
    mammary gland, HET, Female, WTSI
integumental system (1)
  • Brpf3tm1a(EUCOMM)Wtsi
    mammary gland, HET, Female, WTSI
respiratory system (1)
  • Brpf3tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
sensory organ (1)
  • Brpf3tm1a(EUCOMM)Wtsi
    eye, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (82)
  • Brpf3tm1a(EUCOMM)Wtsi
    body, HET, Male, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    head, HET, Male, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    head, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    forearm, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    forearm, HET, Male, WTSI

show all 82 images

Skin Histopathology (3)
  • Brpf3tm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI
  • Brpf3tm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Brpf3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Brpf3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Brpf3tm39782(pL1L2_GT0_DelLacZ_bsd)
Vector
Gene