Gene: Wdr47

Order

Name WD repeat domain 47

Synonyms 1810073M12Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2139593    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Wdr47

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Wdr47 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased grip strength Wdr47tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.79E-9
decreased body weight Wdr47tm1a(EUCOMM)Wtsi HOM Female Male postnatal 4.07E-9
hyperactivity Wdr47tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.5E-7
abnormal behavior Wdr47tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.71E-7
mammalian phenotype Wdr47tm1a(EUCOMM)Wtsi HOM Male postnatal 2.28E-6
increased total body fat amount Wdr47tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.51E-6
increased circulating alkaline phosphatase level Wdr47tm1a(EUCOMM)Wtsi HOM Female Male postnatal 8.32E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No (2/2)
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse respiratory system digestive system nervous system set of connective tissues reproductive system immune system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (19)
  • Wdr47tm1a(EUCOMM)Wtsi
    skin, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    ovary, oviduct, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI

show all 19 images

trunk (12)
  • Wdr47tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    ovary, oviduct, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI

show all 12 images

nervous system (4)
  • Wdr47tm1a(EUCOMM)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    pituitary gland, HET, Male, WTSI
digestive system (3)
  • Wdr47tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
endocrine system (2)
  • Wdr47tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    thyroid gland, HET, Male, WTSI
immune system (2)
  • Wdr47tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    spleen, HET, Male, WTSI
reproductive system (2)
  • Wdr47tm1a(EUCOMM)Wtsi
    ovary, oviduct, HET, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
integumental system (1)
  • Wdr47tm1a(EUCOMM)Wtsi
    skin, HET, Female, WTSI
respiratory system (1)
  • Wdr47tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
set of connective tissues (1)
  • Wdr47tm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI
urinary system (1)
  • Wdr47tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (153)
  • Wdr47tm1a(EUCOMM)Wtsi
    head, HOM, Male, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    head, HOM, Male, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    forearm, HOM, Male, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    body, HOM, Male, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    head, HOM, Male, WTSI

show all 153 images

Brain Histopathology (4)
  • Wdr47tm1a(EUCOMM)Wtsi
    hippocampal commissure, decreased hippocampal commissure size, HOM, Male, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    brain, WT, Male, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    hippocampal commissure, decreased hippocampal commissure size, HOM, Male, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    brain, WT, Male, WTSI
Skin Histopathology (2)
  • Wdr47tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI
  • Wdr47tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Wdr47tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Wdr47tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene