banner
Genes Phenotypes Help, News, Blog

Gene: Cep152 MGI:2139083

Log in to follow
Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
centrosomal protein 152
Synonyms:
N/A

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Cep152 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Cep152 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Seckel Syndrome 5
Cryptorchidism OMIM:613823
Autosomal Recessive Primary Microcephaly
ORPHA:2512
Seckel Syndrome
ORPHA:808
Microcephaly 9, Primary, Autosomal Recessive
OMIM:614852

The table below shows human diseases predicted to be associated to Cep152 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Seckel Syndrome 5
Cryptorchidism OMIM:613823
Autosomal Recessive Primary Microcephaly
ORPHA:2512
Seckel Syndrome
ORPHA:808
Microcephaly 9, Primary, Autosomal Recessive
OMIM:614852

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Cep152

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Cep152.

There are 1 publication which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo. Proceedings of the National Academy of Sciences of the United States of America (March 2014) Cep152tm1a(EUCOMM)Wtsi PMC3992648

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Cep152tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells
Cep152tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cep152tm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter