Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Fn3k by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Pentosuria | Abnormality of urine homeostasis | OMIM:260800 | |
Uridine-Cytidineuria | Elevated urinary uridine level, Elevated urinary cytidine | OMIM:618477 | |
Sedoheptulokinase Deficiency | Increased urinary sedoheptulose | OMIM:617213 | |
Proteinuria, Low Molecular Weight, With Hypercalciuria And Nephrocalcinosis | Renal insufficiency, Hypercalciuria, Nephrocalcinosis, Focal segmental glomerulosclerosis, Aminoa... | OMIM:308990 | |
Proteinuria, Chronic Benign | Albuminuria, Renal insufficiency, Proteinuria | OMIM:618884 | |
Medullary Sponge Kidney | Hematuria, Nephrolithiasis, Distal renal tubular acidosis, Hypercalciuria | ORPHA:1309 | |
Primary Hyperoxaluria Type 3 | Hyperoxaluria, Dysuria, Calcium oxalate nephrolithiasis, Nephrocalcinosis, Hematuria, Pollakisuri... | ORPHA:93600 | |
Nephrolithiasis, Calcium Oxalate, 2, With Or Without Nephrocalcinosis | Nephrocalcinosis, Hyperoxaluria, Nephrolithiasis, Hypocitraturia | OMIM:620374 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Fn3ktm1e(KOMP)Wtsi | Targeted, non-conditional allele | ES Cells |
Fn3ktm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Fn3ktm41850(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
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