Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Prickle2 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
15q13.3 microdeletion syndrome | Seizure | DECIPHER:74 | |
Intellectual Developmental Disorder, Autosomal Dominant 10 | Seizure | OMIM:614256 | |
Kifafa Seizure Disorder | Seizure | OMIM:245180 | |
Intellectual Developmental Disorder, X-Linked 88 | Seizure | OMIM:300852 | |
Epilepsy, Nocturnal Frontal Lobe, 3 | Seizure | OMIM:605375 | |
Glycosylphosphatidylinositol Biosynthesis Defect 16 | Seizure | OMIM:617816 | |
Intellectual Developmental Disorder, X-Linked 96 | Seizure | OMIM:300802 | |
Intellectual Developmental Disorder, Autosomal Recessive 10 | Seizure | OMIM:611096 | |
Intellectual Developmental Disorder, Autosomal Dominant 3 | Seizure | OMIM:612580 | |
Epilepsy, Nocturnal Frontal Lobe, 1 | Focal-onset seizure, Seizure | OMIM:600513 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Prickle2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | ES Cells |
Prickle2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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