Gene: Zfp266

Order

Name zinc finger protein 266

Synonyms
  • 5730601F06Rik
  • 5330440G10Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1924769    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Zfp266

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Zfp266 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Zfp266tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
increased circulating alkaline phosphatase level Zfp266tm1b(EUCOMM)Wtsi HOM Female postnatal 2.26E-13
decreased circulating potassium level Zfp266tm1b(EUCOMM)Wtsi HOM Female postnatal 9.14E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (2/2)
Blood vessel 2 No
Bone 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Eye 2 No (2/2)
Gall bladder 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (1/2)
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No (1/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system endocrine system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (17)
  • Zfp266tm1b(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    trigeminal V nerve, peripheral nervous system, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    gall bladder, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    uterus, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI

show all 17 images

trunk (12)
  • Zfp266tm1b(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    gall bladder, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    uterus, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    heart, HET, Female, WTSI

show all 12 images

digestive system (3)
  • Zfp266tm1b(EUCOMM)Wtsi
    gall bladder, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
nervous system (3)
  • Zfp266tm1b(EUCOMM)Wtsi
    trigeminal V nerve, peripheral nervous system, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    brainstem, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
reproductive system (2)
  • Zfp266tm1b(EUCOMM)Wtsi
    uterus, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
urinary system (2)
  • Zfp266tm1b(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
cardiovascular system (1)
  • Zfp266tm1b(EUCOMM)Wtsi
    heart, HET, Female, WTSI
endocrine system (1)
  • Zfp266tm1b(EUCOMM)Wtsi
    parathyroid gland, HET, Male, WTSI
integumental system (1)
  • Zfp266tm1b(EUCOMM)Wtsi
    skin, HET, Female, WTSI
musculoskeletal system (1)
  • Zfp266tm1b(EUCOMM)Wtsi
    rib, bone, HET, Female, WTSI
respiratory system (1)
  • Zfp266tm1b(EUCOMM)Wtsi
    lung, HET, Female, WTSI
sensory organ (1)
  • Zfp266tm1b(EUCOMM)Wtsi
    eye, HET, Female, WTSI

Associated Images

Associated Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Eye Morphology: Images Ophthalmoscopy
    4 Images
  • X-ray: XRay Images Dorso Ventral
    28 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
Legacy Phenotype Associated Images
Xray (56)
  • Zfp266tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 56 images

Dysmorphology (6)
  • Zfp266tm1b(EUCOMM)Wtsi
    tail, abnormal tail morphology, HOM, Male, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    abnormal coat/hair pigmentation, HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    tail, abnormal tail morphology, HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    abnormal coat/hair pigmentation, HOM, Female, WTSI

show all 6 images

Histology Slide (6)
  • Zfp266tm1b(EUCOMM)Wtsi
    TS20 chorioallantoic placenta, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    TS20 hindbrain, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    TS20 spinal cord, HET, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    TS20 dorsal root ganglion, HET, Male, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    TS20 forebrain, HET, Male, WTSI

show all 6 images

Eye Morphology (5)
  • Zfp266tm1b(EUCOMM)Wtsi
    persistence of hyaloid vascular system, HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    fused cornea and lens, HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    persistence of hyaloid vascular system, HOM, Female, WTSI
  • Zfp266tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Zfp266tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Zfp266tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene