Gene: Vwa5b1

Order

Name von Willebrand factor A domain containing 5B1

Synonyms 4931403E03Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1922968    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Vwa5b1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Vwa5b1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased body weight Vwa5b1tm1a(KOMP)Wtsi HOM Female Male postnatal 1.89E-17

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562) (1/2)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse nervous system reproductive system immune system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (2)
  • Vwa5b1tm1a(KOMP)Wtsi
    KIDNEY, HET, Female, WTSI
  • Vwa5b1tm1a(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
endocrine system (1)
  • Vwa5b1tm1a(KOMP)Wtsi
    THYROID GLAND, HET, Female, WTSI
immune system (1)
  • Vwa5b1tm1a(KOMP)Wtsi
    MESENTERIC LYMPH NODE, LYMPH NODE, HET, Female, WTSI
nervous system (1)
  • Vwa5b1tm1a(KOMP)Wtsi
    BRAIN, HET, Female, WTSI
reproductive system (1)
  • Vwa5b1tm1a(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
urinary system (1)
  • Vwa5b1tm1a(KOMP)Wtsi
    KIDNEY, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (67)
  • Vwa5b1tm1a(KOMP)Wtsi
    HEAD, HOM, Female, WTSI
  • Vwa5b1tm1a(KOMP)Wtsi
    LOWER ARM, HOM, Female, WTSI
  • Vwa5b1tm1a(KOMP)Wtsi
    TRUNK, HOM, Male, WTSI
  • Vwa5b1tm1a(KOMP)Wtsi
    TRUNK, HOM, Male, WTSI
  • Vwa5b1tm1a(KOMP)Wtsi
    HEAD, HOM, Male, WTSI

show all 67 images

Eye Morphology (1)
  • Vwa5b1tm1a(KOMP)Wtsi
    EYE, eyelids fail to open, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Vwa5b1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Vwa5b1tm44150(L1L2_gt1)
Vector
Gene