Gene: Oplah

Order

Name 5-oxoprolinase (ATP-hydrolysing)

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1922725    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Oplah

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Oplah data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
cataract Oplahtm1b(KOMP)Wtsi HOM Male postnatal 6.28E-10
abnormal lens morphology Oplahtm1b(KOMP)Wtsi HOM Female Male postnatal 2.15E-9
increased startle reflex Oplahtm1b(KOMP)Wtsi HOM Female Male postnatal 1.7E-5
decreased grip strength Oplahtm1b(KOMP)Wtsi HOM Male postnatal 6.37E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No (5/393)
Aorta 1 No (1/562)
Blood 1 No
Bone 1 No (1/539)
Bone marrow 1 No
Brain 1 Yes (6/562) (2/2)
Brainstem 1 No (4/562)
Brown adipose tissue 1 No
Cartilage tissue 1 No (1/562)
Cecum 1 No (1/355)
Cerebellum 1 No (4/562)
Cerebral cortex 1 No (5/562)
Chest bone 1 Yes (1/2)
Colon 1 No (1/99) (1/2)
Cranium 1 No (1/2)
Diaphragm 1 No
Epididymis 1 No (4/106)
Esophagus 1 No (2/393)
Eye 1 No (1/562)
Gall bladder 1 No
Harderian gland 1 No
Heart 1 No (3/562)
Hindlimb 1 No
Hippocampus 1 No (5/562)
Hypothalamus 1 No (4/562)
Kidney 1 Yes (20/562) (2/2)
Large intestine 1 No (12/562)
Liver 1 No
Lower urinary tract 1 No (3/562)
Lung 1 Yes (3/562) (2/2)
Lymph node 1 No (1/562)
Main olfactory bulb 1 No
Mammary gland 1 No
Mesenteric lymph node 1 No
Olfactory lobe 1 No (4/393)
Oral epithelium 1 No
Ovary 1 No (1/562)
Oviduct 1 No (2/562)
Pancreas 1 No (6/562)
Parathyroid gland 1 No (2/540)
Parotid gland 1 No
Penis 1 No
Peripheral nervous system 1 No (3/562)
Peyer's patch 1 No (1/393)
Pituitary gland 1 No (1/562)
Prostate gland 1 No (5/562)
Sciatic nerve 1 No
Skeletal muscle 1 No
Skin 1 No (1/562)
Small intestine 1 No (11/562)
Spinal cord 1 No (3/562)
Spleen 1 No (4/562)
Stomach 1 No (9/562) (1/2)
Stomach pyloric region 1 No
Striatum 1 No (4/562)
Sublingual gland 1 No
Submandibular gland 1 No (1/104) (1/2)
Testis 1 No (4/562) (1/2)
Thymus 1 No (1/2)
Thyroid gland 1 No (16/562)
Tongue 1 No
Trachea 1 No (3/562)
Trigeminal V nerve 1 No
Urinary bladder 1 No
Uterus 1 No (2/562)
Vagina 1 No
Vas deferens 1 No (1/360)
Vascular system 1 No (1/393)
Vesicular gland 1 No
White adipose tissue 1 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    digestive system
    nervous system
    reproductive system
    immune system
    musculoskeletal system
    exocrine system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    14 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Oplahtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Oplahtm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene