Gene: Lima1

Order

Name LIM domain and actin binding 1

Synonyms
  • EPLIN
  • 1110021C24Rik
  • 3526402A12Rik
  • epithelial protein lost in neoplasm

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1920992    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Lima1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Lima1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Lima1tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
absent teeth Lima1tm1b(KOMP)Wtsi HOM Female postnatal 2.44E-5
abnormal head morphology Lima1tm1b(KOMP)Wtsi HOM Female postnatal 7.31E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No (2/2)
Bone marrow 2 No
Brain 2 No (2/2)
Brainstem 2 No (1/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No (1/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No (1/2)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system cardiovascular system nervous system sensory organ reproductive system immune system exocrine system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/2)
Dorsal root ganglion 1 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485) (2/2)
Eye 2 (1/485)
Foot 2 (1/485)
Forebrain 2 (1/485) (2/2)
Forelimb 2 (1/485)
Fronto-nasal process 1 (1/48)
Hand 2 (1/485)
Head 2 (5/485) (2/2)
Heart 2 (1/485)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Midbrain 2 (1/485)
Nose 1 (1/51)
Oral cavity 2 (1/485)
Skin 2 (1/485)
Spinal cord 1 (1/50)
Tail 2 (1/485)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    17 Images
  • X-ray: XRay Images Lateral Orientation
    17 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    17 Images
  • Sleep Wake: Wake state (bmp file)
    14 Images
  • Electroretinography 2: Rod and cone PDF
    1 Images
  • Combined SHIRPA and Dysmorphology
    5 Images
  • X-ray: XRay Images Skull Lateral Orientation
    17 Images
  • X-ray: XRay Images Forepaw
    17 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Lima1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Lima1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene