Gene: Hspb11

Order

Name heat shock protein family B (small), member 11

Synonyms
  • 2900042B11Rik
  • IFT25

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1920188    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Hspb11

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Hspb11 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Hspb11tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
abnormal behavior Hspb11tm1a(EUCOMM)Wtsi HET Female postnatal 1.31E-5
increased circulating free fatty acid level Hspb11tm1a(EUCOMM)Wtsi HET Female postnatal 3.54E-5
increased circulating glycerol level Hspb11tm1a(EUCOMM)Wtsi HET Female postnatal 4.04E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system nervous system set of connective tissues reproductive system immune system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (11)
  • Hspb11tm1a(EUCOMM)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    tail, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    oviduct, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI

show all 11 images

trunk (6)
  • Hspb11tm1a(EUCOMM)Wtsi
    oviduct, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    trachea, thyroid gland, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI

show all 6 images

nervous system (4)
  • Hspb11tm1a(EUCOMM)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    spinal cord, HET, Male, WTSI
reproductive system (2)
  • Hspb11tm1a(EUCOMM)Wtsi
    oviduct, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
respiratory system (2)
  • Hspb11tm1a(EUCOMM)Wtsi
    trachea, thyroid gland, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
endocrine system (1)
  • Hspb11tm1a(EUCOMM)Wtsi
    trachea, thyroid gland, HET, Female, WTSI
immune system (1)
  • Hspb11tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
set of connective tissues (1)
  • Hspb11tm1a(EUCOMM)Wtsi
    cartilage tissue, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (174)
  • Hspb11tm1a(EUCOMM)Wtsi
    body, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    forearm, WT, Male, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    forearm, WT, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    body, HET, Female, WTSI
  • Hspb11tm1a(EUCOMM)Wtsi
    head, HET, Female, WTSI

show all 174 images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Hspb11tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene