Gene: Kat14


Name lysine acetyltransferase 14

  • Csrp2bp
  • D2Ertd473e
  • 2510008M08Rik
  • D2Wsu131e
  • ATAC2

Status ES CellsMice
phenotype data available

Links MGI:1917264    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Kat14

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Kat14 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Kat14tm1a(KOMP)Wtsi HOM Female Male n/a 0.0
eyelids fail to open Kat14tm1a(KOMP)Wtsi HOM Male postnatal 2.52E-10
abnormal eyelid aperture Kat14tm1a(KOMP)Wtsi HOM Male postnatal 5.43E-10
abnormal eye size Kat14tm1a(KOMP)Wtsi HOM Male postnatal 1.51E-9
decreased body weight Kat14tm1a(KOMP)Wtsi HOM Female Male postnatal 8.35E-9
decreased body length Kat14tm1a(KOMP)Wtsi HOM Female Male postnatal 1.33E-8
abnormal cornea morphology Kat14tm1a(KOMP)Wtsi HOM Female postnatal 1.12E-7
decreased lean body mass Kat14tm1a(KOMP)Wtsi HOM Female Male postnatal 2.12E-7
corneal opacity Kat14tm1a(KOMP)Wtsi HOM Female postnatal 3.11E-6
abnormal cranium morphology Kat14tm1a(KOMP)Wtsi HOM Male postnatal 8.53E-6
abnormal eye pigmentation Kat14tm1a(KOMP)Wtsi HOM Female Male postnatal 1.31E-5
abnormal eye morphology Kat14tm1a(KOMP)Wtsi HOM Male postnatal 1.78E-5
abnormal iris morphology Kat14tm1a(KOMP)Wtsi HOM Male postnatal 1.94E-5
decreased bone mineral content Kat14tm1a(KOMP)Wtsi HOM Female Male postnatal 2.83E-5
abnormal maxilla morphology Kat14tm1a(KOMP)Wtsi HOM Male postnatal 7.77E-5

Download data as: TSV XLS


IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No (1/2)
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse nervous system musculoskeletal system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab

Associated Images

Phenotype associated images not available

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Kat14tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)