Gene: Emc10

Order

Name ER membrane protein complex subunit 10

Synonyms
  • 2310044H10Rik
  • Mirta22
  • 5430410O10Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1916933    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Emc10

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Emc10 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased neutrophil cell number Emc10tm1b(EUCOMM)Wtsi HOM Female Male postnatal 8.81E-13
abnormal gait Emc10tm1b(EUCOMM)Wtsi HOM Female postnatal 2.84E-12
thrombocytopenia Emc10tm1b(EUCOMM)Wtsi HOM Male postnatal 4.31E-12
abnormal locomotor behavior Emc10tm1b(EUCOMM)Wtsi HOM Female postnatal 1.36E-8
increased eosinophil cell number Emc10tm1b(EUCOMM)Wtsi HOM Female postnatal 2.21E-8
decreased mean corpuscular volume Emc10tm1b(EUCOMM)Wtsi HOM Female postnatal 3.22E-7
decreased lymphocyte cell number Emc10tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.62E-6
abnormal vocalization Emc10tm1b(EUCOMM)Wtsi HOM Female postnatal 6.93E-6
thin ventricular wall Emc10tm1b(EUCOMM)Wtsi HOM Female postnatal 8.4E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No
Gall bladder 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    respiratory system
    digestive system
    cardiovascular system
    nervous system
    set of connective tissues
    reproductive system
    exocrine system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (4/4)
Ear 2 (1/485) (2/4)
Embryo 2 (1/485) (4/4)
Eye 2 (1/485) (4/4)
Foot 2 (1/485) (2/4)
Forebrain 2 (1/485) (4/4)
Forelimb 2 (1/485) (4/4)
Hand 2 (1/485) (2/4)
Head 2 (5/485) (4/4)
Heart 2 (1/485) (2/4)
Hindbrain 2 (6/485) (4/4)
Hindlimb 2 (1/485) (4/4)
Liver 2 (1/485) (2/4)
Lung 2 (1/485) (2/4)
Mandibular process 2 (1/485) (2/4)
Maxillary process 2 (1/485) (2/4)
Midbrain 2 (1/485) (4/4)
Oral cavity 2 (1/485) (2/4)
Skin 2 (1/485) (2/4)
Tail 2 (1/485) (4/4)
Tail somite 2 (1/485) (4/4)


Associated Images

Associated Images
  • Echo: M-Mode Images
    28 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    20 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Emc10tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Emc10tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene