Gene: Zc3hc1

Order

Name zinc finger, C3HC type 1

Synonyms
  • 1110054L24Rik
  • HSPC216
  • Nipa

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1916023    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Zc3hc1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Zc3hc1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
male infertility Zc3hc1tm1a(KOMP)Wtsi HOM Male postpartum stage 0.0
decreased body weight Zc3hc1tm1a(KOMP)Wtsi HOM Female Male postnatal 2.77E-9
abnormal snout morphology Zc3hc1tm1a(KOMP)Wtsi HOM Female postnatal 6.69E-7
decreased rib number Zc3hc1tm1a(KOMP)Wtsi HOM Female Male postnatal 1.55E-5
abnormal cornea morphology Zc3hc1tm1a(KOMP)Wtsi HOM Female postnatal 2.73E-5
abnormal posture Zc3hc1tm1a(KOMP)Wtsi HOM Female Male postnatal 3.32E-5
increased heart weight Zc3hc1tm1a(KOMP)Wtsi HET Male postnatal 5.44E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No (2/2)
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (1/2)
Trachea 2 No (3/562) (2/2)
Uterus 2 No (2/562) (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system endocrine system cardiovascular system nervous system set of connective tissues reproductive system musculoskeletal system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (7)
  • Zc3hc1tm1a(KOMP)Wtsi
    HEART, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    UTERUS, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    ADRENAL GLAND, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    THYMUS, HET, Female, WTSI

show all 7 images

nervous system (4)
  • Zc3hc1tm1a(KOMP)Wtsi
    PITUITARY GLAND, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    BRAIN, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    BRAIN, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    SPINAL CORD, HET, Male, WTSI
endocrine system (2)
  • Zc3hc1tm1a(KOMP)Wtsi
    ADRENAL GLAND, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    THYROID GLAND, HET, Female, WTSI
reproductive system (2)
  • Zc3hc1tm1a(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    UTERUS, HET, Female, WTSI
cardiovascular system (1)
  • Zc3hc1tm1a(KOMP)Wtsi
    HEART, HET, Female, WTSI
immune system (1)
  • Zc3hc1tm1a(KOMP)Wtsi
    THYMUS, HET, Female, WTSI
musculoskeletal system (1)
  • Zc3hc1tm1a(KOMP)Wtsi
    SKELETAL MUSCLE TISSUE, HET, Female, WTSI
urinary system (1)
  • Zc3hc1tm1a(KOMP)Wtsi
    KIDNEY, HET, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (119)
  • Zc3hc1tm1a(KOMP)Wtsi
    LOWER ARM, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    TRUNK, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    TRUNK, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    HEAD, HET, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    HEAD, HET, Female, WTSI

show all 119 images

Skin Histopathology (2)
  • Zc3hc1tm1a(KOMP)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI
  • Zc3hc1tm1a(KOMP)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI
Eye Morphology (1)
  • Zc3hc1tm1a(KOMP)Wtsi
    EYE, eyelids fail to open, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Zc3hc1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Zc3hc1tm295765(L1L2_Bact_P)
Vector
Gene
Zc3hc1tm37311(L1L2_Bact_P)
Vector
Gene