Gene: Mybphl

Name myosin binding protein H-like

Synonyms 1110037P11Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1916003   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Mybphl

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mybphl data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Mybphltm1a(KOMP)Wtsi HOM Female Male n/a 0.0
preweaning lethality, incomplete penetrance Mybphltm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased grip strength Mybphltm1a(KOMP)Wtsi HOM Female Male postnatal 1.67E-8
thrombocytosis Mybphltm1a(KOMP)Wtsi HOM Female Male postnatal 1.56E-5
decreased blood urea nitrogen level Mybphltm1b(KOMP)Wtsi HET Female Male postnatal 3.87E-5
decreased circulating fructosamine level Mybphltm1b(KOMP)Wtsi HET Female Male postnatal 5.49E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No
Aorta 4 No (1/562)
Blood vessel 4 No
Bone 4 No (1/539)
Brain 4 No (5/562)
Brainstem 4 No (4/562)
Brown adipose tissue 4 No
Cartilage tissue 4 No (1/562)
Cerebellum 4 No (4/562)
Cerebral cortex 4 No (5/562)
Eye 4 No (1/562)
Gall bladder 4 No
Heart 4 No (3/562) (4/4)
Hippocampus 4 No (5/562)
Hypothalamus 4 No (4/562)
Kidney 4 No (19/562)
Large intestine 4 No (12/562)
Liver 4 No
Lower urinary tract 4 No (3/562)
Lung 4 No (3/562) (2/4)
Lymph node 4 No (1/562)
Mammary gland 4 No
Esophagus 4 No
Olfactory lobe 4 No
Ovary 4 No (1/562)
Oviduct 4 No (2/562)
Pancreas 4 No (6/562)
Parathyroid gland 4 No (2/540)
Peripheral nervous system 4 No (3/562)
Peyer's patch 4 No
Pituitary gland 4 No (1/562)
Prostate gland 4 No (5/562)
Skeletal muscle tissue 4 No
Skin 4 No (1/562)
Small intestine 4 No (11/562)
Spinal cord 4 No (3/562)
Spleen 4 No (4/562)
Stomach 4 No (9/562)
Striatum 4 No (4/562)
Testis 4 No (3/562) (1/4)
Thymus 4 No
Thyroid gland 4 No (16/562)
Trachea 4 No (3/562)
Uterus 4 No (2/562)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system cardiovascular system reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (6)
  • Mybphltm1a(KOMP)Wtsi
    OVARY, HET, Female, WTSI
  • Mybphltm1a(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
  • Mybphltm1a(KOMP)Wtsi
    HEART, HET, Female, WTSI
  • Mybphltm1b(KOMP)Wtsi
    LUNG, HET, Female, WTSI
  • Mybphltm1b(KOMP)Wtsi
    KIDNEY, HET, Female, WTSI

show all 6 images

cardiovascular system (2)
  • Mybphltm1a(KOMP)Wtsi
    HEART, HET, Female, WTSI
  • Mybphltm1b(KOMP)Wtsi
    HEART, HET, Female, WTSI
reproductive system (2)
  • Mybphltm1a(KOMP)Wtsi
    OVARY, HET, Female, WTSI
  • Mybphltm1a(KOMP)Wtsi
    TESTIS, HET, Male, WTSI
adipose tissue (1)
  • Mybphltm1b(KOMP)Wtsi
    WHITE ADIPOSE TISSUE, HET, Female, WTSI
respiratory system (1)
  • Mybphltm1b(KOMP)Wtsi
    LUNG, HET, Female, WTSI
set of connective tissues (1)
  • Mybphltm1b(KOMP)Wtsi
    WHITE ADIPOSE TISSUE, HET, Female, WTSI
urinary system (1)
  • Mybphltm1b(KOMP)Wtsi
    KIDNEY, HET, Female, WTSI

Associated Images

Associated Images
  • Anti-nuclear antibody assay
    7 Images
  • Eye Morphology: Images Slit Lamp
    5 Images
  • X-ray: XRay Images Dorso Ventral
    86 Images
  • X-ray: XRay Images Lateral Orientation
    58 Images
  • X-ray: XRay Images Forepaw
    28 Images
  • X-ray: XRay Images Skull Lateral Orientation
    29 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    29 Images
  • Eye Morphology: Images Ophthalmoscopy
    2 Images
Legacy Phenotype Associated Images
Xray (144)
  • Mybphltm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Mybphltm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Mybphltm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Mybphltm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Mybphltm1a(KOMP)Wtsi
    HOM, Male, WTSI

show all 144 images

Eye Morphology (7)
  • Mybphltm1a(KOMP)Wtsi
    persistence of hyaloid vascular system, HOM, Female, WTSI
  • Mybphltm1a(KOMP)Wtsi
    abnormal cornea morphology, HOM, Female, WTSI
  • Mybphltm1a(KOMP)Wtsi
    RIGHT EYE, HOM, Female, WTSI
  • Mybphltm1b(KOMP)Wtsi
    Fused cornea and lens, HET, Female, WTSI
  • Mybphltm1b(KOMP)Wtsi
    abnormal cornea morphology, HET, Male, WTSI

show all 7 images

Histology Slide (3)
  • Mybphltm1b(KOMP)Wtsi
    HET, Male, WTSI
  • Mybphltm1a(KOMP)Wtsi
    HET, Unsexed, WTSI
  • Mybphltm1b(KOMP)Wtsi
    HET, Female, WTSI
Embryo Dysmorphology (1)
  • Mybphltm1b(KOMP)Wtsi
    HOM, Male, WTSI
Skin Histopathology (1)
  • Mybphltm1a(KOMP)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Mybphltm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Mybphltm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Mybphltm41446(L1L2_gt1)
Vector
Gene