Gene: Gcsh

Order

Name glycine cleavage system protein H (aminomethyl carrier)

Synonyms
  • 1100001L02Rik
  • 5730591C18Rik

Status ES CellsMice
em1
phenotype data available

Links MGI:1915383    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Gcsh

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gcsh data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Gcshem1(IMPC)H HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Gcshem1(IMPC)H HOM Female Male n/a 0.0
prolonged RR interval Gcshem1(IMPC)H HET Female Male postnatal 1.23E-6
increased mean corpuscular volume Gcshem1(IMPC)H HET Female Male postnatal 3.13E-6
decreased heart rate Gcshem1(IMPC)H HET Female Male postnatal 3.0E-5
decreased circulating alkaline phosphatase level Gcshem1(IMPC)H HET Female postnatal 4.41E-5
increased basophil cell number Gcshem1(IMPC)H HET Female Male postnatal 7.52E-5
short tibia Gcshem1(IMPC)H HET Female Male postnatal 8.3E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    7 Images
  • X-ray: XRay Images Skull Lateral Orientation
    2 Images
  • X-ray: XRay Images Lateral Orientation
    7 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gcshem1(IMPC)H Exon Deletion
Vector
Gene
Gcshtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Gcshtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Gcshtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene