Gene: Rnaseh2b

Order

Name ribonuclease H2, subunit B

Synonyms
  • 1110019N06Rik
  • 2610207P08Rik
  • Dleu8

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1914403    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Rnaseh2b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rnaseh2b data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Rnaseh2btm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
abnormal vibrissa morphology Rnaseh2btm1a(EUCOMM)Wtsi HET Female postnatal 7.54E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562) (1/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse nervous system reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
nervous system (4)
  • Rnaseh2btm1a(EUCOMM)Wtsi
    BRAIN, HET, Male, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    PERIPHERAL NERVOUS SYSTEM, HET, Male, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    BRAIN, HET, Male, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Male, WTSI
trunk (4)
  • Rnaseh2btm1a(EUCOMM)Wtsi
    THYMUS, HET, Male, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    KIDNEY, HET, Male, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Male, WTSI
immune system (1)
  • Rnaseh2btm1a(EUCOMM)Wtsi
    THYMUS, HET, Male, WTSI
reproductive system (1)
  • Rnaseh2btm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
urinary system (1)
  • Rnaseh2btm1a(EUCOMM)Wtsi
    KIDNEY, HET, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (86)
  • Rnaseh2btm1a(EUCOMM)Wtsi
    TRUNK, HET, Female, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    TRUNK, HET, Female, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    HEAD, HET, Female, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    HEAD, HET, Female, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    LOWER ARM, HET, Female, WTSI

show all 86 images

Skin Histopathology (6)
  • Rnaseh2btm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, WT, Female, WTSI
  • Rnaseh2btm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI

show all 6 images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rnaseh2btm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rnaseh2btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene