Gene: Med28

Name mediator complex subunit 28

Synonyms
  • 1500003D12Rik
  • Eg1
  • magicin

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1914249   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Med28

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Med28 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Med28tm1.1(KOMP)Vlcg HET Female Male embryonic day 9.5 0.0
abnormal spleen morphology Med28tm1.1(KOMP)Vlcg HET Male postnatal 0.0
embryonic lethality prior to organogenesis Med28tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Med28tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Med28tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
small spleen Med28tm1.1(KOMP)Vlcg HET Male postnatal 0.0
increased or absent threshold for auditory brainstem response Med28tm1.1(KOMP)Vlcg HET Female Male postnatal 3.0E-6
increased body length Med28tm1.1(KOMP)Vlcg HET Male postnatal 1.72E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 7 (5/413) Image Only
Ear 7 Image Only
Embryo 7 Image Only
Eye 7 Image Only
Foot 7 Image Only
Forebrain 7 Image Only
Forelimb 7 Image Only
Hand 7 Image Only
Head 7 (4/413) Image Only
Heart 7 Image Only
Hindbrain 7 (5/413) Image Only
Hindlimb 7 Image Only
Liver 7 Image Only
Lung 7 Image Only
Mandibular process 7 Image Only
Maxillary process 7 Image Only
Midbrain 7 Image Only
Oral cavity 7 Image Only
Skin 7 Image Only
Tail 7 Image Only
Tail somite 7 Image Only


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    28 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Med28tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Med28tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Med28tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene