Gene: Rwdd1

Order

Name RWD domain containing 1

Synonyms
  • 2700069A07Rik
  • 2610002D06Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1913771    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Rwdd1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rwdd1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased CD8-positive, alpha-beta T cell number Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
decreased Ly6C-positive mature NK cell number Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
increased CD4-positive, alpha beta T cell number Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
increased memory-marker gamma-delta T cell number Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
abnormal bone structure Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 7.73E-7
increased circulating alkaline phosphatase level Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 8.29E-7
decreased bone mineral content Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 3.91E-6
decreased lean body mass Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 9.09E-6
thrombocytopenia Rwdd1tm1b(KOMP)Wtsi HOM Female Male postnatal 1.08E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (3)
  • Rwdd1tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    pancreas, HET, Female, WTSI
trunk (3)
  • Rwdd1tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    pancreas, HET, Female, WTSI
reproductive system (1)
  • Rwdd1tm1b(KOMP)Wtsi
    testis, HET, Male, WTSI
urinary system (1)
  • Rwdd1tm1b(KOMP)Wtsi
    kidney, HET, Female, WTSI

Associated Images

Associated Images
  • Spleen Immunophenotyping: Images associated with FACS analysis
    15 Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • Eye Morphology: Images Slit Lamp
    6 Images
  • Eye Morphology: Images Ophthalmoscopy
    13 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (85)
  • Rwdd1tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    HOM, Male, WTSI

show all 85 images

Eye Morphology (19)
  • Rwdd1tm1b(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Female, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Female, WTSI

show all 19 images

Dysmorphology (2)
  • Rwdd1tm1b(KOMP)Wtsi
    abnormal coat/hair pigmentation, HOM, Male, WTSI
  • Rwdd1tm1b(KOMP)Wtsi
    abnormal coat/hair pigmentation, HOM, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rwdd1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rwdd1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene