Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Wdr7.
There are 3 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
WDR72 regulates vesicle trafficking in ameloblasts. | Scientific reports (February 2022) | Wdr72tm1a(KOMP)Wtsi | PMC8857301 |
WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation. | Nature communications (January 2019) | Wdr76tm1a(EUCOMM)Hmgu | PMC6336889 |
WDR72 models of structure and function: a stage-specific regulator of enamel mineralization. | Matrix biology : journal of the International Society for Matrix Biology (July 2014) | Wdr72tm1a(KOMP)Wtsi | PMC4185229 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Wdr7tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | ES Cells |
Wdr7tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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